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946.
In a preceding study it has been reported that the freshwater sponge Lubomirskia baicalensis, living in Lake Baikal (East Siberia), is composed of spicules forming a characteristic pattern which follows radiate accretive growth. Here we report that the spicules are synthesized by the enzyme silicatein, a protein which is related to cathepsin L. The cDNAs for silicatein and the related cathepsin L were isolated and used as probes to show that the mRNA levels of silicatein in the bases of the spicule skeleton of the animals are low, while the mRNA level of cathepsin L in this region exceeds that of the growing zone. This is the first comprehensive study on the importance of the axial filament/silicatein as an essential structural and functional component determining the growth and stability of demosponge spicules.Note: Sequences from Lubomirskia baicalensis have been deposited in the EMBL/GenBank; cDNAs for the putative silicatein (LBSILICA) are deposited under the accession no. AJ786771 and for cathepsin L (LBCATL) under the accession no. AJ786770.  相似文献   
947.
Food production has to be increased in a sustainable way to meet the future global demand. A key position is attributed to developing countries. A deepened understanding of their agricultural regions with specific resource endowments and constraints is therefore crucial. In this study we propose a methodology based on material flux analysis (MFA) to assess the resource potentials and limitations of a Nicaraguan agricultural region. We focus on current regional and farm resource management and explore them under two scenarios. Indicators are nitrogen and the degrees of self-sufficiency (DSS) for energy, and the staples maize and beans. As data is scarce, most information is based on interviews with farmers of four categories and key persons, and on literature. The results show that nitrogen management does not differ considerably among categories. Nitrogen is mined mostly from staple plots. Self-sufficiency for beans is given in an average year. Yet, landless and small farmers neither produce enough maize for autoconsumption, nor are they self-sufficient for firewood. Energy supply is also the core problem of the region, since the DSS is 70%. Soil nitrogen stocks last at most for three more generations. Analyses with the scenario technique show that: (a) Unlimited population growth has serious consequences in the near future e.g. severe shortage of energy and food. (b) Alternative farming systems are possible, but they require reducing the population by a factor 2, and thus the creation of jobs in a Hinterland. Readers should send their comments on this paper to: BhaskarNath@aol.com within 3 months of publication of this issue.  相似文献   
948.
The mental health consequences of exposure to traumatic events and the risk factors for psychological morbidity among expatriate and Kosovar Albanian humanitarian aid workers have not been well studied. In June 2000, we used standardised screening tools to survey 285 (69.5%) of 410 expatriate aid workers and 325 (75.8%) of 429 Kosovar Albanian aid workers from 22 humanitarian organizations that were implementing health programmes in Kosovo. The mean number of trauma events experienced by expatriates was 2.8 (standard deviation: 2.7) and by Kosovar staff 3.2 (standard deviation: 2.8). Although only 1.1% of expatriate and 6.2% of Kosovar aid workers reported symptoms consistent with the diagnosis for post-traumatic stress disorder, 17.2% and 16.9%, respectively, reported symptoms satisfying the definition of depression. Regression analysis demonstrated that the number of trauma events experienced was significantly associated with depression for the two sets of workers. Organisational support services may be an important mediating factor and should be targeted at both groups.  相似文献   
949.
Harvey PA  Reed RA 《Disasters》2005,29(2):129-151
Environmental sanitation programmes are vital for tackling environmental-related disease and ensuring human dignity in emergency situations. If they are to have maximum impact they must be planned in a rapid but systematic manner. An appropriate planning process comprises five key stages: rapid assessment and priority setting; outline programme design; immediate action; detailed programme design; and implementation. The assessment should be based on carefully selected data, which are analysed via comparison with suitable minimum objectives. How the intervention should be prioritised is determined through objective ranking of different environmental sanitation sector needs. Next, a programme design outline is produced to identify immediate and longer-term intervention activities and to guarantee that apposite resources are made available. Immediate action is taken to meet acute emergency needs while the detailed programme design takes shape. This entails in-depth consultation with the affected community and comprehensive planning of activities and resource requirements. Implementation can then begin, which should involve pertinent management and monitoring strategies.  相似文献   
950.
Walker P 《Disasters》2005,29(4):323-336
This paper reflects on the genesis of the Code of Conduct for the International Red Cross and Red Crescent Movement and Non-Governmental Organizations (NGOs) in Disaster Relief, on the tenth anniversary of its adoption. The origins, usage and future of the code are examined with respect to three debates, current at the time of its inception, namely: the debate about the core content of humanitarianism; the debate about coherence and the consensual nature of the humanitarian community; and the debate about the need for, and the ability to demonstrate, accountability. The paper concludes that although the Code of Conduct was very much a product of its time, its content remains relevant today. However, its future application hinges on the capacity of those who purport to follow it to realise true accountability, and on proving that the code, written essentially for natural disasters, is relevant to contemporary complex emergencies.  相似文献   
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