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131.
Ingrid Witters Philippe Moerman Maximilian Muenke Frans-André Van Assche Koen Devriendt Eric Legius Dominique Van Schoubroeck Jean-Pierre Fryns 《黑龙江环境通报》2001,21(10):839-841
We report the prenatal echographic diagnosis of holoprosencephaly (HPE) at 11 weeks' gestation. Fetopathological examination revealed an unusual variant of semilobar HPE with middle interhemispheric fusion associated with sex-reversal: 46,XY normal male karyotype, normal external and internal female genitalia and streak gonads. Copyright © 2001 John Wiley & Sons, Ltd. 相似文献
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Estienney Marie Daval-Frerot Philippe Aho-Glélé Ludwig-Serge Piroth Lionel Stabile Pascal Gerbet Jean-Yves Rouleau Romain de Rougemont Alexis Belliot Gaël 《Food and environmental virology》2022,14(2):217-221
Food and Environmental Virology - Disinfection of hospital facilities and ambulances is an important issue for breaking the chain of transmission of viral pathogens. Hydrogen peroxide has provided... 相似文献
137.
Economic Analysis of Summer Fallow Management to Reduce Take-All Disease and N Leaching in a Wheat Crop Rotation 总被引:1,自引:0,他引:1
Stéphane De Cara Florence Jacquet Arnaud Reynaud Gaël Goulevant Marie-Hélène Jeuffroy Françoise Montfort Philippe Lucas 《Environmental Modeling and Assessment》2011,16(1):91-105
This paper addresses the question of summer cover-crop adoption by farmers in presence of a risk of yield loss due to take-all disease and climate variability. To analyze the public incentives needed to encourage farmers to adopt summer cover crops as a means of reducing N leaching, we combine outputs from an economic, an epidemiological and an agronomic model. The economic model is a simple model of choice under risk. The farmer is assumed to choose among a range of summer fallow managements and input uses on the basis of the expected utility criterion (HARA assumption) in presence of both climate and take-all risks. The epidemiological model proposed by Ennaïfar et al. (Eur J Plant Pathol 118:127–143, 2007) is used to determine the impact of take all on yields and N uptake. The crop-soil model (STICS) is used to compute yield developments and N leaching under various management options and climatic conditions. The input parameters are chosen to match the conditions prevailing in Grignon, located in the main wheat-growing area in France. Eight management systems are examined: four summer fallow managements: ‘wheat volunteers’ (WV), ‘bare soil’ (BS), ‘early mustard’, ‘late mustard’, and two input intensities. We show that the optimal systems are BS (WV) when the take-all risk is (not) taken into account by agents. We then compute the minimum payment to each system such that it emerges in the optimum. We thus derive the required amounts of transfer needed to trigger catch-crop adoption. The results of the Monte Carlo sensitivity analysis show that the ranking of management systems is robust over a wide range of input parameters. 相似文献
138.
Priadi C Bourgeault A Ayrault S Gourlay-Francé C Tusseau-Vuillemin MH Bonté P Mouchel JM 《Journal of environmental monitoring : JEM》2011,13(5):1470-1479
In order to obtain representative dissolved and solid samples from the aquatic environment, a spectrum of sampling methods are available, each one with different advantages and drawbacks. This article evaluates the use of discrete sampling and time-integrated sampling in illustrating medium-term spatial and temporal variation. Discrete concentration index (CI) calculated as the ratio between dissolved and solid metal concentrations in grab samples are compared with time-integrated concentration index (CI) calculated from suspended particulate matter (SPM) collected in sediment traps and labile metals measured by the diffusive gel in thin films (DGT) method, collected once a month during one year at the Seine River, upstream and downstream of the Greater Paris Region. Discrete CI at Bougival was found to be significantly higher than at Triel for Co, Cu, Mn, Ni and Zn, while discrete metal partitioning at Marnay was found to be similar to Bougival and Triel. However, when using time-integrated CI, not only was Bougival CI significantly higher than Triel CI, CI at Marnay was also found to be significantly higher than CI at Triel which was not observed for discrete CI values. Since values are time-averaged, dramatic fluctuations were smoothed out and significant medium-term trends were enhanced. As a result, time-integrated concentration index (CI) was able to better illustrate urbanization impact between sites when compared to discrete CI. The impact of significant seasonal phenomenon such as winter flood, low flow and redox cycles was also, to a certain extent, visible in time-integrated CI values at the upstream site. The use of time-integrated concentration index may be useful for medium- to long-term metal studies in the aquatic environment. 相似文献
139.
Spatial connectivity in a large river system: resolving the sources and fate of dissolved organic matter 总被引:1,自引:0,他引:1
Large rivers are generally heterogeneous and productive systems that receive important inputs of dissolved organic matter (DOM) from terrestrial and in situ sources. Thus, they are likely to play a significant role in the biogeochemical cycling of the DOM flowing to the oceans. The asymmetric spatial gradient driven by directional flow and environmental heterogeneity contributes to the fate of DOM flowing downstream. Yet, the relative effects of spatial connectivity and environmental heterogeneity on DOM dynamics are poorly understood. For example, since environmental variables show spatial heterogeneity, the variation explained by environmental and spatial variables may be redundant. We used the St. Lawrence River (SLR) as a representative large river to resolve the unique influences of environmental heterogeneity and spatial connectivity on DOM dynamics. We used three-dimensional fluorescence matrices combined with parallel factor analysis (PARAFAC) to characterize the DOM pool in the SLR. Seven fluorophores were modeled, of which two were identified to be of terrestrial origin and three from algal exudates. We measured a set of environmental variables that are known to drive the fate of DOM in aquatic systems. Additionally, we used asymmetric eigenvector map (AEM) modeling to take spatial connectivity into account. The combination of spatial and environmental models explained 85% of the DOM variation. We show that spatial connectivity is an important driver of DOM dynamics, as a large fraction of environmental heterogeneity was attributable to the asymmetric spatial gradient. Along the longitudinal axis, we noted a rapid increase in dissolved organic carbon (DOC), mostly controlled by terrestrial input of DOM originating from the tributaries. Variance partitioning demonstrated that freshly produced protein-like DOM was found to be the preferential substrate for heterotrophic bacteria undergoing rapid proliferation, while humic-like DOM was more correlated to the diffuse attenuation coefficient of UVA radiation. 相似文献
140.
In the present study, we demonstrate an integrated modeling approach for predicting internal tissue concentrations of chemicals
by coupling a multimedia environmental model and a generic physiologically based pharmacokinetic (PBPK) model. A case study
was designed for a region situated on the Seine river watershed, downstream of the Paris megacity, and for benzo(a)pyrene
emitted from industrial zones in the region. In this case study, these two models are linked only by water intake from riverine
system for the multimedia model into human body for the PBPK model. The limited monitoring data sets of B(a)P concentrations
in bottom sediment and in raw river water, obtained at the downstream of Paris, were used to re-construct long-term daily
concentrations of B(a)P in river water. The re-construction of long-term series of B(a)P level played a key role for the intermediate
model calibration (conducted in multimedia model) and thus for improving model input to PBPK model. In order to take into
account the parametric uncertainty in the model inputs, some input parameters relevant for the multimedia model were given
by probability density functions (PDFs); some generic PDFs were updated with site-specific measurements by a Bayesian approach.
The results of this study showed that the multimedia model fits well with actual annual measurements in sediments over one
decade. No accumulation of B(a)P in the organs was observed. In conclusion, this case study demonstrated the feasibility of
a full-chain assessment combining multimedia environmental predictions and PBPK modeling, including uncertainty and sensitivity
analyses. 相似文献