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41.
42.
The high per capita generation of solid waste and the environmental problems in major rural communities of Ensenada, Baja California, have prompted authorities to seek alternatives for waste treatment. In the absence of a selection methodology, three technologies of waste treatment with energy recovery (an anaerobic digester, a downdraft gasifier, and a plasma gasifier) were evaluated, taking the broader social, political, economic, and environmental issues into considerations. Using the scientific literature as a baseline, interviews with experts, decision makers and the community, and waste stream studies were used to construct a hierarchy that was evaluated by the analytic hierarchy process. In terms of the criteria, judgments, and assumptions made in the model, the anaerobic digester was found to have the highest rating and should consequently be selected as the waste treatment technology for this area. The study results showed low sensitivity, so alternative scenarios were not considered. The methodology developed in this study may be useful for other governments who wish to assess technologies to select waste treatment.  相似文献   
43.
Pet animal management is subject to varied husbandry practices and the resulting consequences often impact negatively on animal welfare. The perceptions held by someone who proposes to keep an animal regarding the ease or difficulty with which its biological needs can be provided for in captivity are key factors in whether that animal is acquired and how well or poorly it does. We propose a system to ‘score’ animals and assign them to categories indicating the ease or difficulty with which they can be kept as pets in accordance with welfare and public health and safety considerations. The ‘EMODE’ (‘Easy’, ‘Moderate’, ‘Difficult’, ‘Extreme’) system has two fundamental components: animal welfare—which considers the ‘five freedoms’ principles; and public health and safety—which considers management associated with risks from disease or injury to the keeper and to others. EMODE incorporates two tiers of assessment and guidance, and may offer a reasonable guide for the majority of relevant animals. EMODE Tier 1 provides a primary and general assessment of animals by class or group, and EMODE Tier 2 provides a secondary refined assessment of animals by species or breed. EMODE offers a user-friendly and versatile foundation concept for the future development of guidance for the layperson who may be considering acquiring a pet or for certain personnel when considering assigning species to restrictive lists of suitable animals, for example, ‘positive lists’ as used by governments to control animals in trade and keeping.  相似文献   
44.

Objective

To evaluate the test accuracy of non-invasive prenatal testing (NIPT) for fetal trisomy 21, 18, and 13 using cell-free (cf) DNA analysis in maternal plasma with microarray quantitation.

Method

Systematic review and meta-analysis. Searches in MEDLINE, Pre-MEDLINE, EMBASE, Web of Science, and the Cochrane Library to 09.07.2018.

Results

Five studies analyzing 3074 samples, including 187 trisomy 21, 43 trisomy 18, and 19 trisomy 13 cases, were identified. Risk of bias was high in all studies, introduced particularly by exclusions from analysis and by the role of the sponsor. Sensitivity of microarray-based cfDNA testing was 99.5% (95%CI 96.3%-99.9%) for trisomy 21, 97.7% (95%CI 87.9%-99.6%) for trisomy 18, and 100% (95%CI 83.2%-100%) for trisomy 13. Specificity was 100% (95% CI 99.87%-100%) for trisomy 21, 99.97% (95%CI 99.81%-99.99%) for trisomy 18, and 99.97% (95%CI 99.81%-99.99%) for trisomy 13. Pooled test failure rate was 1.1%. A direct comparison of microarray- and sequencing-based cfDNA found equivalent test accuracy.

Conclusion

Included studies suggest that NIPT using microarray-based cfDNA testing has high sensitivity and specificity for detecting fetal trisomy 21, 18, and 13. However, the evidence base is small and at high risk of bias.  相似文献   
45.
We investigate stream response to the La Valle Dam removal and channel reconstruction by estimating channel hydraulic parameter values and changes in sedimentation within the reservoir. The designed channel reconstruction after the dam removal included placement of a riffle structure at the former dam site. Stream surveys undertaken in 1984 by Federal Emergency Management Agency and in 2001 by Doyle et al. were supplemented with surveys in 2009 and 2011 to study the effects of the instream structure. We created a model in HEC‐RAS IV and surface maps in Surfer© using the 1984, 2009, and 2011 surveys. The HEC‐RAS IV model for 2009 channel conditions indicates that the riffle structure decreases upstream channel shear stress and velocity, causing renewed deposition of sediment within the former reservoir. We estimate by 2009, 61% of former reservoir sediments were removed during dam removal and channel reconstruction. Between 2009 and 2011 renewed sedimentation within the former reservoir represented approximately 7.85% of the original reservoir volume. The HEC‐RAS IV models show the largest impacts of the dam and riffle structure occur at flood magnitudes at or below bankfull. Thus, the riffle and the dam similarly alter channel hydraulics and sediment transport. As such, our models indicate that the La Valle Dam project was a dam replacement rather than a removal. Our results confirm that channel reconstruction method can alter channel hydraulics, geomorphology, and sediment mobility.  相似文献   
46.
INTRODUCTION: This study explores the differences in injury severity between male and female drivers, and across the different age groups, in single-vehicle accidents involving passenger cars. METHOD: Given the occurrence of an accident, separate male and female multinomial logit models of injury severity (with possible outcomes of no injury, injury, and fatality) were estimated for young (ages 16 to 24), middle-aged (ages 25 to 64), and older (ages 65 and older) drivers. RESULTS: The estimation results show statistically significant differences in the factors that determine injury-severity levels between male and female drivers and among the different driver age groups. CONCLUSIONS: We discuss a number of plausible explanations for the observed age/gender differences and provide suggestions for future work on the subject. IMPACT ON INDUSTRY: A better understanding of age and gender differences can lead to improvements in vehicle and highway design to minimize driver injury severity. This paper provides some new evidence to help unravel this complex problem.  相似文献   
47.
The Dutch policy objective of a fully sustainable livestock sector without mutilations by 2023 is not compatible with the routine practice of tail docking to minimize the risk of tail biting. To examine farmer attitudes towards docking, a telephone survey was conducted among 487 conventional and 33 organic Dutch pig farmers. “Biting” (of tails, ears, or limbs) was identified by the farmers as a main welfare problem in pig farming. About half of the farmers reported to have no tail biting problems in their own herd. When farmers did report problems, they most often reported figures between 1 and 5 % of the animals. High incidences of tail biting were anticipated when trying to keep undocked pigs. Enrichment materials used in the conventional sector included mainly chains (52–63 % of the farms) and hanging rubber or plastic balls (22–30 %). Straw, sawdust, or wood shavings was hardly provided in conventional pig farming (2–3 %), in contrast to organic farming (88–100 % of farms). Conventional pig farmers feel a curly tail is not very important for sustainable pig farming. They consider enrichment to be less effective and tail docking to be less stressful for them and their piglets than their organic colleagues do. Pig farmers identified climate as a main risk factor for tail biting as opposed to enrichment. The objective of reducing routine tail docking requires solutions for dealing with tail biting problems at the farm level. In this process, transfer of scientific knowledge about enrichment materials and other measures to prevent and cure tail biting is critical, as is a change in farmer attitudes and awareness of the moral issues involved.  相似文献   
48.
Genetic diversity within species represents a fundamental yet underappreciated level of biodiversity. Because genetic diversity can indicate species resilience to changing climate, its measurement is relevant to many national and global conservation policy targets. Many studies produce large amounts of genome-scale genetic diversity data for wild populations, but most (87%) do not include the associated spatial and temporal metadata necessary for them to be reused in monitoring programs or for acknowledging the sovereignty of nations or Indigenous peoples. We undertook a distributed datathon to quantify the availability of these missing metadata and to test the hypothesis that their availability decays with time. We also worked to remediate missing metadata by extracting them from associated published papers, online repositories, and direct communication with authors. Starting with 848 candidate genomic data sets (reduced representation and whole genome) from the International Nucleotide Sequence Database Collaboration, we determined that 561 contained mostly samples from wild populations. We successfully restored spatiotemporal metadata for 78% of these 561 data sets (n = 440 data sets with data on 45,105 individuals from 762 species in 17 phyla). Examining papers and online repositories was much more fruitful than contacting 351 authors, who replied to our email requests 45% of the time. Overall, 23% of our email queries to authors unearthed useful metadata. The probability of retrieving spatiotemporal metadata declined significantly as age of the data set increased. There was a 13.5% yearly decrease in metadata associated with published papers or online repositories and up to a 22% yearly decrease in metadata that were only available from authors. This rapid decay in metadata availability, mirrored in studies of other types of biological data, should motivate swift updates to data-sharing policies and researcher practices to ensure that the valuable context provided by metadata is not lost to conservation science forever.  相似文献   
49.
Technical assessments of vulnerability and/or risk are increasingly being undertaken to assess the impacts of climate change. Underlying this is the belief that they will bring clarity to questions regarding the scale of institutional investments required, plausible adaptation policies and measures, and the timing of their implementation. Despite the perceived importance of technical assessments in 'evidence-based' decision environments, assessments cannot be undertaken independent of values and politics, nor are they capable of eliminating the uncertainty that clouds decision-making on climate adaptation As such, assessments can trigger as many questions as they answer, leaving practitioners and stakeholders to question their value. This paper explores the value of vulnerability/risk assessments in climate change adaptation planning processes as a catalyst for learning in four case studies in Southeastern Australia. Data were collected using qualitative interviews with stakeholders involved in the assessments and analysed using a social learning framework. This analysis revealed that detailed and tangible strategies or actions often do not emerge directly from technical assessments. However, it also revealed that the assessments became important platforms for social learning. In providing these platforms, assessments present opportunities to question initial assumptions, explore multiple framings of an issue, generate new information, and galvanise support for collective actions. This study highlights the need for more explicit recognition and understanding of the important role social learning plays in climate change vulnerability assessments and adaptation planning more broadly.  相似文献   
50.
Abstract

Objective: The objective of this research study is to estimate the benefit to pedestrians if all U.S. cars, light trucks, and vans were equipped with an automated braking system that had pedestrian detection capabilities.

Methods: A theoretical automatic emergency braking (AEB) model was applied to real-world vehicle–pedestrian collisions from the Pedestrian Crash Data Study (PCDS). A series of potential AEB systems were modeled across the spectrum of expected system designs. Both road surface conditions and pedestrian visibility were accounted for in the model. The impact speeds of a vehicle without AEB were compared to the estimated impact speeds of vehicles with a modeled pedestrian detecting AEB system. These impacts speeds were used in conjunction with an injury and fatality model to determine risk of Maximum Abbreviated Injury Scale of 3 or higher (MAIS 3+) injury and fatality.

Results: AEB systems with pedestrian detection capability, across the spectrum of expected design parameters, reduced fatality risk when compared to human drivers. The most beneficial system (time-to-collision [TTC]?=?1.5?s, latency = 0?s) decreased fatality risk in the target population between 84 and 87% and injury risk (MAIS score 3+) between 83 and 87%.

Conclusions: Though not all crashes could be avoided, AEB significantly mitigated risk to pedestrians. The longer the TTC of braking and the shorter the latency value, the higher benefits showed by the AEB system. All AEB models used in this study were estimated to reduce fatalities and injuries and were more effective when combined with driver braking.  相似文献   
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