Pelvic restraint cushion sled test evaluation of pelvic forward motion

Objective: This study was designed to evaluate the performance of a pelvic restraint cushion (PRC), a submarining countermeasure that deploys under the thighs when a crash is detected in order to block the forward motion of the pelvis.

Methods: Sled tests approximating low- and high-speed frontal impacts were conducted with 4 female postmortem human subjects (PMHS) restrained by a lap and shoulder belt in the right front passenger seat. The subjects were tested with and without a PRC.

Results: The PRC is effective in reducing forward motion of the PMHS pelvis and reduces the risk of injury due to lap belt loading in a high-speed frontal crash.

Conclusions: Although small sample size limits the utility of the study's findings, the results suggest that the PRC can limit pelvic forward motion and that pelvic injury due to PRC deployment is not likely.     

Reservoir Sedimentation Rates in the Little Washita River Experimental Watershed,Oklahoma: Measurement and Controlling Factors

Forty‐five flood control reservoirs, authorized in the Watershed Protection and Flood Prevention Act 1954, were installed by United States Department of Agriculture (USDA) between 1969 and 1982 in the Little Washita River Experimental Watershed (LWREW), located in central Oklahoma. Over time, these reservoirs have lost sediment and flood storage capacity due to sedimentation, with rates dependent on upstream land use and climate variability. In this study, sedimentation rates for 12 reservoirs representing three major land use categories within LWREW were measured based on bathymetric surveys that used acoustic profiling system. Physiographic and climate attributes of drainage area of surveyed reservoirs were extracted from publicly available data sources including topographic maps, digital elevation models, USDA Natural Resource Conservation Service soils, and weather station databases. Correlation, principal component analysis, and stepwise regression were utilized to analyze the relationship between normalized reservoir sedimentation rates (ReSRa) and the drainage area characteristics to determine the major variables controlling sedimentation within the LWREW. Percent of drainage area with extreme slopes, saturated hydraulic conductivity, and maximum daily rainfall event recorded in spring explained most of the variability in ReSRa. It was also found that percent reduction in reservoir surface area can be used as a surrogate for estimating ReSRa. The implications of the results are discussed.     

Characterizing Uncertainty in Daily Streamflow Estimates at Ungauged Locations for the Massachusetts Sustainable Yield Estimator

Hydrologic characterization at ungauged locations is one of the quintessential challenges of hydrology. Beyond simulation of historical streamflows, it is similarly important to characterize the level of uncertainty in hydrologic estimates. In tandem with updates to Massachusetts Sustainable Yield Estimator, this work explores the application of global uncertainty estimates to daily streamflow simulations. Expanding on a method developed for deterministic modeling, this approach produces confidence intervals on daily streamflow developed through nonlinear spatial interpolation of daily streamflow using flow duration curves; the 95% confidence is examined. Archived cross‐validations of daily streamflows from 66 watersheds in and around Massachusetts are used to evaluate an approach to uncertainty characterization. Neighboring sites are treated as ungauged, producing relative errors that can be resampled and applied to target sites. The method, with some modification, is found to provide appropriately narrow confidence intervals that contain 95% of the observed streamflows in cross‐validation. Further characterizing uncertainty, multiday means of daily streamflow are evaluated. Working through cross‐validation in Massachusetts, two‐ to three‐month averages of daily streamflow show the best performance. These two approaches to uncertainty characterization inform how streamflow simulation produced for prediction in ungauged basins can be used for water resources management.     

Challenges to measuring,monitoring, and addressing the cumulative impacts of artisanal and small-scale gold mining in Ecuador

Portovelo-Zaruma, Ecuador is an artisanal and small-scale gold mining (ASGM) region with approximately 6000 gold miners working with mercury and cyanide. Although artisanal gold mining (AGM) has taken place in Portovelo-Zaruma for centuries, highly mechanized small-scale gold mining (SGM) processing plants capable of increased throughput began being built in the 1990s. While there are benefits associated with ASGM, there are also negative impacts experienced by the miners and the surrounding communities. To take advantage of ASGM as a poverty-alleviating mechanism while reducing unwanted externalities, the cumulative impacts must be understood. Numerous challenges to measuring, monitoring, and addressing ASGM impacts result from the complexity of the impacts themselves, the nature of the gold mining as an informal industry, and the shortfalls in the current regulatory framework. These are discussed in the context of ongoing, unresolved issues including efforts to address trans-boundary water pollution, management of mining waste, and conflicts regarding priorities, ambiguities, and enforcement of existing regulations and policies. Internationally, interventions to address both AGM and SGM impacts have typically focused almost exclusively on technological changes through the elimination of mercury use. Our analysis suggests that to better address ASGM and their cumulative impacts in Ecuador, it will be beneficial to revisit the legal definitions of AGM and SGM. Additionally, promotion of information-based strategies including educational outreach programs and cross-scale and cross-level mitigation methods may also be beneficial. The success of these strategies to reduce ASGM-related cumulative impacts will depend on sufficient funding and the commitment of stakeholders.     

Environmental impact assessment of non-wood based pulp production by soda-anthraquinone pulping process

Paper pulp manufacturing is the main non-food industrial utilization of plant biomass. Non-wood and agricultural residues are potential raw materials in the production of specialty papers. This chapter aims to quantify the environmental impacts associated with non-wood high quality paper pulp manufacture via soda-anthraquinone (AQ) cooking process by means of the application of LCA methodology in a cradle-to-gate analysis. Hemp (Cannabis sativa) and Flax (Linum usitatissimum) were evaluated as raw materials for the production of high quality non-porous pulp. A specialty paper pulp mill was analysed in detail and process chain was divided in six subsystems: agricultural activities, chemicals production, electricity production, transport, pulp production and waste treatment. Inventory data came from interviews and surveys (on-site measurements). When necessary, the data were completed with bibliographic resources.Abiotic resources depletion (AD), global warming (GW), ozone layer depletion (OLD), human toxicity (HT), ecotoxicity, photochemical oxidant formation (POF), acidification (A) and eutrophication (E) were the impact categories analysed in this study. According to the results, the environmental impact is mainly caused by the production of chemicals, electricity and fibres (agricultural activities) due to greenhouse gases emissions, phosphorous and nitrogen compounds emissions. The activities inside the pulp mill present minor contribution to almost all impact categories, excluding GW (15%) and E (6%) as well as OLD (25%). This study provides useful information for non-wood based industries related not only to pulp manufacture but also to panels or biorefineries with the aim of increasing their sustainability.     

How does cell-based non-invasive prenatal test (NIPT) perform against chorionic villus sampling and cell-free NIPT in detecting trisomies and copy number variations? A clinical study from Denmark

Objectives

We aimed to compare cell-based NIPT (cbNIPT) to chorionic villus sampling (CVS) and to examine the test characteristics of cbNIPT in the first clinical validation study of cbNIPT compared to cell-free NIPT (cfNIPT).

Material and Methods

Study 1: Women (N = 92) who accepted CVS were recruited for cbNIPT (53 normal and 39 abnormal). Samples were analyzed with chromosomal microarray (CMA). Study 2: Women (N = 282) who accepted cfNIPT were recruited for cbNIPT. cfNIPT was analyzed using sequencing and cbNIPT by CMA.

Results

Study 1: cbNIPT detected all aberrations (32/32) found in CVS: trisomies 13, 18 and 21 (23/23), pathogenic copy number variations (CNVs) (6/6) and sex chromosome aberrations (3/3). cbNIPT detected 3/8 cases of mosaicism in the placenta. Study 2: cbNIPT detected all trisomies found with cfNIPT (6/6) and had no false positive (0/246). One of the three CNVs called by cbNIPT was confirmed by CVS but was undetected by cfNIPT, two were false positives. cbNIPT detected mosaicism in five samples, of which two were not detected by cfNIPT. cbNIPT failed in 7.8% compared to 2.8% in cfNIPT.

Conclusion

Circulating trophoblasts in the maternal circulation provide the potential of screening for aneuploidies and pathogenic CNVs covering the entire fetal genome.     

Perceptions of urban climate hazards and their effects on adaptation agendas

Decision-makers in cities around the world are beginning to take steps to adapt to the current and future risks presented by climate change, the sum of which we refer to as a city’s adaptation agenda. However, there is significant variation in such agendas: some may focus on responding to one or two climate hazards, while others develop agendas to respond to a wide range of hazards. What causes this varying range of urban adaptation agendas? The purpose of this study is to assess how geographic, socioeconomic, and institutional features of cities as well as the perception of climate change hazards affect the scope of adaptation agendas. Utilizing regression analyses of a newly constructed database for 58 cities around the world, our findings suggest that the perception of climate change hazards held by decision-makers is a primary determinant of the scope of urban adaptation agendas. Given that each global city faces place-specific hazards from varying extreme climate events, this research provides global-scale adaptation strategies for local, national, and international institutions, suggesting that enhancing awareness as well as mapping urban climate hazards is an initial step for broadening and mainstreaming adaptation agendas.     

The innate responses of bumble bees to flower patterns: separating the nectar guide from the nectary changes bee movements and search time

Nectar guides can enhance pollinator efficiency and plant fitness by allowing pollinators to more rapidly find and remember the location of floral nectar. We tested if a radiating nectar guide around a nectary would enhance the ability of naïve bumble bee foragers to find nectar. Most experiments that test nectar guide efficacy, specifically radiating linear guides, have used guides positioned around the center of a radially symmetric flower, where nectaries are often found. However, the flower center may be intrinsically attractive. We therefore used an off-center guide and nectary and compared “conjunct” feeders with a nectar guide surrounding the nectary to “disjunct” feeders with a nectar guide separated from the nectary. We focused on the innate response of novice bee foragers that had never previously visited such feeders. We hypothesized that a disjunct nectar guide would conflict with the visual information provided by the nectary and negatively affect foraging. Approximately, equal numbers of bumble bees (Bombus impatiens) found nectar on both feeder types. On disjunct feeders, however, unsuccessful foragers spent significantly more time (on average 1.6-fold longer) searching for nectar than any other forager group. Successful foragers on disjunct feeders approached these feeders from random directions unlike successful foragers on conjunct feeders, which preferentially approached the combined nectary and nectar guide. Thus, the nectary and a surrounding nectar guide can be considered a combination of two signals that attract naïve foragers even when not in the floral center.