全文获取类型
收费全文 | 215篇 |
免费 | 4篇 |
专业分类
安全科学 | 3篇 |
废物处理 | 6篇 |
环保管理 | 11篇 |
综合类 | 69篇 |
基础理论 | 66篇 |
污染及防治 | 45篇 |
评价与监测 | 10篇 |
社会与环境 | 8篇 |
灾害及防治 | 1篇 |
出版年
2023年 | 12篇 |
2022年 | 8篇 |
2021年 | 3篇 |
2020年 | 4篇 |
2019年 | 6篇 |
2018年 | 12篇 |
2017年 | 15篇 |
2016年 | 11篇 |
2015年 | 11篇 |
2014年 | 11篇 |
2013年 | 19篇 |
2012年 | 15篇 |
2011年 | 25篇 |
2010年 | 6篇 |
2009年 | 8篇 |
2008年 | 13篇 |
2007年 | 4篇 |
2006年 | 9篇 |
2005年 | 7篇 |
2004年 | 3篇 |
2003年 | 8篇 |
2002年 | 4篇 |
2001年 | 1篇 |
2000年 | 1篇 |
1999年 | 1篇 |
1996年 | 2篇 |
排序方式: 共有219条查询结果,搜索用时 156 毫秒
11.
Joe Shaw Elizabeth Scotchman Ben Paternoster Maureen Ramos Sarah Nesbitt Sophie Sheppard Tristan Snowsill Lyn S. Chitty Natalie Chandler 《黑龙江环境通报》2023,43(4):477-488
Objectives
To develop a flexible droplet digital PCR (ddPCR) workflow to perform non-invasive prenatal diagnosis via relative mutation dosage (RMD) for maternal pathogenic variants with a range of inheritance patterns, and to compare the accuracy of multiple analytical approaches.Methods
Cell free DNA (cfDNA) was tested from 124 archived maternal plasma samples: 88 cases for sickle cell disease and 36 for rare Mendelian conditions. Three analytical methods were compared: sequential probability ratio testing (SPRT), Bayesian and z-score analyses.Results
The SPRT, Bayesian and z-score analyses performed similarly well with correct prediction rates of 96%, 97% and 98%, respectively. However, there were high rates of inconclusive results for each cohort, particularly for z-score analysis which was 31% overall. Two samples were incorrectly classified by all three analytical methods; a false negative result predicted for a fetus affected with sickle cell disease and a false positive result predicting the presence of an X-linked IDS variant in an unaffected fetus.Conclusions
ddPCR can be applied to RMD for diverse conditions and inheritance patterns, but all methods carry a small risk of erroneous results. Further evaluation is required both to reduce the rate of inconclusive results and explore discordant results in more detail. 相似文献12.
13.
14.
15.
Aude Tessier Mélie Sarreau Fanny Pelluard Gwenaelle André Sophie Blesson Martine Bucourt Pierre Dechelotte Laurence Faivre Thierry Frébourg Alice Goldenberg Valérie Goua Corinne Jeanne-Pasquier Fabien Guimiot Annie Laquerriere Nicole Laurent Mathilde Lefebvre Philippe Loget Martine Maréchaud Charlotte Mechler Marie-Josée Perez Jean Christophe Sabourin Alain Verloes Sophie Patrier Anne-Marie Guerrot 《黑龙江环境通报》2016,36(13):1270-1275
16.
17.
Kfoury Miriana Auezova Lizette Greige-Gerges Hélène Fourmentin Sophie 《Environmental Chemistry Letters》2019,17(1):129-143
Environmental Chemistry Letters - There is a growing interest for aromatic and biological properties of essential oils as alternatives to synthetic chemicals and drugs. However, essential oils and... 相似文献
18.
19.
20.