Development of a Computationally Efficient Full Human Body Finite Element Model

Introduction: A simplified and computationally efficient human body finite element model is presented. The model complements the Global Human Body Models Consortium (GHBMC) detailed 50th percentile occupant (M50-O) by providing kinematic and kinetic data with a significantly reduced run time using the same body habitus.

Methods: The simplified occupant model (M50-OS) was developed using the same source geometry as the M50-O. Though some meshed components were preserved, the total element count was reduced by remeshing, homogenizing, or in some cases omitting structures that are explicitly contained in the M50-O. Bones are included as rigid bodies, with the exception of the ribs, which are deformable but were remeshed to a coarser element density than the M50-O. Material models for all deformable components were drawn from the biomechanics literature. Kinematic joints were implemented at major articulations (shoulder, elbow, wrist, hip, knee, and ankle) with moment vs. angle relationships from the literature included for the knee and ankle. The brain of the detailed model was inserted within the skull of the simplified model, and kinematics and strain patterns are compared.

Results: The M50-OS model has 11 contacts and 354,000 elements; in contrast, the M50-O model has 447 contacts and 2.2 million elements. The model can be repositioned without requiring simulation. Thirteen validation and robustness simulations were completed. This included denuded rib compression at 7 discrete sites, 5 rigid body impacts, and one sled simulation. Denuded tests showed a good match to the experimental data of force vs. deflection slopes. The frontal rigid chest impact simulation produced a peak force and deflection within the corridor of 4.63 kN and 31.2%, respectively. Similar results vs. experimental data (peak forces of 5.19 and 8.71 kN) were found for an abdominal bar impact and lateral sled test, respectively. A lateral plate impact at 12 m/s exhibited a peak of roughly 20 kN (due to stiff foam used around the shoulder) but a more biofidelic response immediately afterward, plateauing at 9 kN at 12 ms. Results from a frontal sled simulation showed that reaction forces and kinematic trends matched experimental results well. The robustness test demonstrated that peak femur loads were nearly identical to the M50-O model. Use of the detailed model brain within the simplified model demonstrated a paradigm for using the M50-OS to leverage aspects of the M50-O. Strain patterns for the 2 models showed consistent patterns but greater strains in the detailed model, with deviations thought to be the result of slightly different kinematics between models. The M50-OS with the deformable skull and brain exhibited a run time 4.75 faster than the M50-O on the same hardware.

Conclusions: The simplified GHBMC model is intended to complement rather than replace the detailed M50-O model. It exhibited, on average, a 35-fold reduction in run time for a set of rigid impacts. The model can be used in a modular fashion with the M50-O and more broadly can be used as a platform for parametric studies or studies focused on specific body regions.     

The difference conservation makes to extinction risk of the world's ungulates

Previous studies show that conservation actions have prevented extinctions, recovered populations, and reduced declining trends in global biodiversity. However, all studies to date have substantially underestimated the difference conservation action makes because they failed to account fully for what would have happened in the absence thereof. We undertook a scenario‐based thought experiment to better quantify the effect conservation actions have had on the extinction risk of the world's 235 recognized ungulate species. We did so by comparing species’ observed conservation status in 2008 with their estimated status under counterfactual scenarios in which conservation efforts ceased in 1996. We estimated that without conservation at least 148 species would have deteriorated by one International Union for Conservation of Nature (IUCN) Red List category, including 6 species that now would be listed as extinct or extinct in the wild. The overall decline in the conservation status of ungulates would have been nearly 8 times worse than observed. This trend would have been greater still if not for conservation on private lands. While some species have benefited from highly targeted interventions, such as reintroduction, most benefited collaterally from conservation such as habitat protection. We found that the difference conservation action makes to the conservation status of the world's ungulate species is likely to be higher than previously estimated. Increased, and sustained, investment could help achieve further improvements.     

Relationships between regulated DBPs and emerging DBPs of health concern in U.S. drinking water

A survey was conducted at eight U.S. drinking water plants, that spanned a wide range of water qualities and treatment/disinfection practices. Plants that treated heavily-wastewater-impacted source waters had lower trihalomethane to dihaloacetonitrile ratios due to the presence of more organic nitrogen and HAN precursors. As the bromide to total organic carbon ratio increased, there was more bromine incorporation into DBPs. This has been shown in other studies for THMs and selected emerging DBPs (HANs), whereas this study examined bromine incorporation for a wider group of emerging DBPs (haloacetaldehydes, halonitromethanes). Moreover, bromine incorporation into the emerging DBPs was, in general, similar to that of the THMs. Epidemiology studies that show an association between adverse health effects and brominated THMs may be due to the formation of brominated emerging DBPs of heath concern. Plants with higher free chlorine contact times before ammonia addition to form chloramines had less iodinated DBP formation in chloraminated distribution systems, where there was more oxidation of the iodide to iodate (a sink for the iodide) by the chlorine. This has been shown in many bench-scale studies (primarily for iodinated THMs), but seldom in full-scale studies (where this study also showed the impact on total organic iodine. Collectively, the THMs, haloacetic acids, and emerging DBPs accounted for a significant portion of the TOCl, TOBr, and TOI; however, ∼50% of the TOCl and TOBr is still unknown. The correlation of the sum of detected DBPs with the TOCl and TOBr suggests that they can be used as reliable surrogates.     

Structure of pathways in ecological networks: relationships between length and number

In ecosystems network, structure determines adjacent (direct) and non-adjacent (indirect) pathways over which energy, matter, and information can flow. The more pathways, the more possible ways the conservative substance can move in zero-sum transactions between network nodes that the pathways interconnect, and the more possible non-conservative, nonzero-sum relations can be secondarily derived from these. Structural analysis is a tool we employ, from a family of input–output methods for exploring zero- and nonzero-sum attributes of environmental networks, to count pathways of varying length between network nodes. In this paper, we examine the relationship between pathway length (k) and number (P_k) as determined by system size (n, number of nodes) and extent and pattern of connectance (C). We develop a measure (m_a) of pathway growth in numbers with increasing length, and then normalize this to the maximum rate possible (m_a/m_c) for a given system size. These measures apply to two pathway types—paths, m_a(0) and m_a(0)/m_c(0), which forbid adjacent node repetitions, and walks, m_a(1) and m_a(1)/m_c(1), which allow them. We find that network size has a curvilinear effect on the pathway number versus length relationship, and extent and pattern of connectance are convolved. Values computed for the paths and walks of three ecosystem models (oyster reef, freshwater marsh, and reservoir cove) are used to compare their pathway structure.     

Introduction History and Invasion Patterns of Ammophila arenaria on the North Coast of California

European beachgrass ( Ammophila arenaria [L] Link), introduced to stabilize sand, is fully naturalized in central and northern California and has supplanted populations of native dune plants in many areas, including the North Spit of Humboldt Bay. We interpreted air photos of the North Spit for the presence of Ammophila arenaria at three points in time: 1939/1942, 1962, and 1989. To quantify the spread and to detect invasion patterns of Ammophila , we then compiled maps using a geographic information system. We documented introduction dates and locations to improve the accuracy of our photo interpretation. Interpretation of the three photo series revealed invasion and expansion of Ammophila in both foredunes and inland dunes. The most dramatic increase in cover was found in the foredunes, whereas documented and presumed plantings were found mostly on inland dunes. Adjusting for intentional eradication, Ammophila cover on the North Spit was found to have increased between 1939 and 1989 by 574%. The square root of the area occupied by Ammophila on the North Spit increased linearly with time, conforming to biological invasion theory.     

The selective advantages of cannibalism in a Neotropical mosquito

We investigated the benefits of larval cannibalism in the Neotropical mosquito Trichoprosopon digitatum. The clutch size of the mosquito in the field was strongly correlated with adult female size, indicating a fitness advantage to being large. In controlled laboratory experiments, we compared the survivorship and eventual adult sizes of larvae that were given the opportunity to cannibalise conspecifics throughout their lifetimes with the survivorship and adult sizes of larvae that were prevented from cannibalising. Since the benefits of cannibalism are likely to depend on the context in which it occurs, the experiment was conducted at two levels of alternative food availability. When food availability was high most larvae survived to adulthood, females cannibalised more than males and there was no measurable advantage to cannibalism in terms of survival rate, emergence time or adult size. Larvae were significantly more cannibalistic when food availability was lower, although under these conditions no larvae survived to adulthood. Nevertheless, under low food an important fitness benefit to cannibalism was revealed: individuals which had the opportunity to cannibalise survived significantly longer as larvae than those which did not. This increased longevity is likely to provide an important advantage to mosquito larvae when they wait for the input of unpredictable food sources. Received: 7 October 1995/Accepted after revision: 13 April 1996