Allergies to molds caused by fungal spores in air conditioning equipment

People suffering from various symptoms while in air-conditioned rooms often show sensitizations to fungi that can be isolated when the fungi are dremoved from air conditioners. By using specific challenge tests it was shown that fungal spores in air conditioners can evoke allergic symptoms. Hyposensitization was the specific therapy prescribed for such allergic reactions. After hyposensitization therapy, more than 70% of the patients so treated could live and work again in air-conditioned rooms without developing specific symptoms.     

75 Jahre Theorie des expandierenden Kosmos: Friedmann Modelle und der “Einstein–Limit”

  Die geschichtliche Entwicklung der kosmologischen Modelle für den homogen–isotropen Kosmos, beginnend mit Alexander Friedmanns epochalen Arbeiten (1922 und 1924) bis zur heutigen Diskussion aktueller Modelle wird dargestellt. Eine kardinale Rolle spielt die offene Frage: Besteht die Materie des Kosmos zum weit überwiegenden Teil aus nicht–baryonischer (sog. exotischer) Dunkel–Materie oder reicht die gesamte baryonische Materie aus, die aus den bekannten Atomen und Molekülen besteht, um die Entwicklung des Kosmos zu verstehen. Auch von der normalen (baryonischen) Materie im Kosmos ist nur ein geringer Anteil (etwa 20 5 Prozent) in leuchtenden Objekten (Sterne, Gas, Staub) direkt beobachtbar. Im Abschnitt 3 wird der “Einstein–Limit” für die kosmologische Konstante erl?utert und eine leicht einsichtige Herleitung des Zahlenwertes gegeben.     

德国北部苍鹰(Accipiter gentilis)卵中有机氯残留减少(1971～2002)和卵壳指数增加

我们于1988～2002年对未孵化的苍鹰卵(n=57)进行了调查,并与1971～1978年的卵(n=134)进行了比较,早期PCBs、∑DDT和HCB的浓度为(mg/kg脂重)50.1、126.6和117.7,而后期相应的值显著低,分别为27.7、4.1和0.1.但最近8～10年内,PCB的浓度相对稳定.残留物浓度波动在巢内低于巢间.年龄不影响卵中污染物的积累.1971～1978年测得的卵壳指数显著低,而2001～2002年测得的指数却相当高,与18世纪末的数字相当.我们提出了卵壳指数效应浓度的临界值.DDT族残留物对每处鸟巢的离巢幼鸟数目有影响.     

Three- versus two-dimensional ultrasound for nuchal translucency thickness measurements: comparison of feasibility and levels of agreement

We have determined feasibility and levels of agreement for visualizing the nuchal translucency within a time limit with three-dimensional (3D) and two-dimensional (2D) transvaginal ultrasound. A total of 213 women of median gestational age 13 weeks (range 11–14 weeks) undergoing first-trimester nuchal translucency (NT) thickness measurements with 2D transabdominal ultrasound were included in the study. Additionally all women underwent 2D and 3D transvaginal NT examination within a time limit of 90 s. These two methods were compared with each other and with our standard method (2D transabdominal ultrasound) with respect to visualization of fetal nuchal fold and to the levels of agreement. The nuchal fold was visualized by 3D and 2D transvaginal ultrasound in 85.9% (95% CI: 80.5%, 90.3%) and 25.8% (95% CI: 20.1%, 32.2%), respectively (p<0.001). There was a statistically significant underestimation of the NT by 2D transabdominal as compared with 3D transvaginal ultrasound of 0.1 mm (p<0.001), and by 3D transvaginal as compared with 2D transvaginal ultrasound of even 0.1 mm (p<0.001). 3D transvaginal ultrasound of the nuchal fold has increased feasibility to 2D transvaginal ultrasound within a short examination time and with minimal, but significant, measurement differences. Copyright © 2001 John Wiley & Sons, Ltd.     

Training future experts in “biodiversity and ecosystem services”: a progress report

Biodiversity is essential for multiple aspects of human life and well-being, but many current assessments of the functioning of biodiversity and ecosystems, understanding of risks posed by environmental change and the best practice of their management of ecosystems are lacking a unified scientific and conceptual basis. Methods such as scenario analysis, and terms such as ecosystem services, are widely used, but their meaning is understood in many different ways depending on context, user needs and experience of researchers. In order to advance the conceptual basis for ecosystem analysis and management in a rapidly changing world, as well as the ability of young scientists to reflect upon these concepts, we have organised five 2-week-long summer schools in Peyresq, a remote village in the Southern French Alps. In total 173 participants have worked intensively with 69 experienced researchers and a team of conveners and tutors in order to discuss a broad range of views on topics on ecosystem analysis and functioning. Topics ranged from conditions of and threats to various ecosystems due to environmental change, models and scenarios for assessment, stakeholder perceptions and needs for information, to the social and economic contexts for biodiversity. We report our experience from these schools, present the training concept which has emerged from them and suggest lines of further development.

Bioreactor systems for thermophilic fermentative hydrogen production: evaluation and comparison of appropriate systems

Numerous different bioreactor systems are applied for hydrogen production by dark fermentation. Thermophilic fermentations are gaining an increased interest due to the high hydrogen yields associated with them. In order to reach the best thermophilic fermentation system, 2 types of bioreactors, a trickling bed and a fluidized bed system, were constructed and operated under similar conditions. Both systems were designed to meet the requirements of thermophilic fermentations, such as reduction of hydrogen partial pressure, system immanence as its best as well as increasing cell densities. For comparing the 2 systems, the extreme thermophilic organism Caldicellulosiruptor owensensis OL^T and a glucose-containing medium were employed. Parameters like hydraulic retention time, glucose concentration and stripping gas amount were varied. Each bioreactor system exhibited certain advantages; the trickling bed system enabled yields close to 3 mol-H₂ (mol-glucose)^?1 and productivities of 0.2 L L^?1 h^?1, but the application of stripping gas seemed to be obligatory. The fermentations in the fluidized bed system were characterized by slightly higher productivities (0.25 L L^?1 h^?1), but generally lower yields. However, operation of this system without stripping gas was possible.     

Magnetoreception in birds: no intensity window in “fixed direction” responses

Under 502 nm turquoise light combined with 590 nm yellow light and in total darkness, European robins, Erithacus rubecula, no longer prefer their migratory direction, but exhibit so-called fixed direction responses that do not show the seasonal change between spring and autumn. We tested robins under these light conditions in the local geomagnetic field of 46 μT, a field of twice this intensity, 92 μT, and a field of three times this intensity, 138 μT. Under all three magnetic conditions, the birds preferred the same easterly direction under turquoise-and-yellow light and the same northwesterly direction under dark, while they were oriented in their seasonally appropriate direction under control conditions. “Fixed direction” responses are thus not limited to a narrow intensity window as has been found for normal compass orientation. This can be attributed to their origin in the magnetite-based receptor in the upper beak, which operates according to fundamentally different principles than the radical pair mechanism in the retina mediating compass orientation. “Fixed direction” responses are possibly a relict of a receptor mechanism that changed its function, now mainly providing information on magnetic intensity.     

Precipitation-driven decrease in wildfires in British Columbia

Trends of summer precipitation and summer temperature and their influence on trends in summer drought and area burned in British Columbia (BC) were investigated for the period 1920–2000. The complexity imposed by topography was taken into account by incorporating high spatial resolution climate and fire data. Considerable regional variation in trends and in climate–fire relationships was observed. A weak but significant increase in summer temperature was detected in northeastern and coastal BC, whereas summer precipitation increased significantly in all regions—by up to 45.9 %. A significant decrease in province-wide area burned and at the level of sub-units was strongly related to increasing precipitation, more so than to changing temperature or drought severity. A stronger dependence of area burned on precipitation, a variable difficult to predict, implies that projected changes in future area burned in this region may yield higher uncertainties than in regions where temperature is predominantly the limiting factor for fire activity. We argue that analyses of fire–climate relationships must be undertaken at a sufficiently high resolution such that spatial variability in limiting factors on area burned like precipitation, temperature, and drought is captured within units.