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291.
Environmental Science and Pollution Research - In 2017, the 19th National Congress of the Communist Party of China put forward the concept of high-quality economic development, indicating that the...  相似文献   
292.

Polycyclic aromatic hydrocarbon (PAH) exposure and genetic susceptibility were conductive to genotoxic effects including gene damage, which can increase mutational probability. We aimed to explore the dose-effect associations of PAH exposure with damage of exons of epidermal growth factor receptor (EGFR) and breast cancer susceptibility gene 1 (BRCA1), as well as their associations whether modified by Flap endonuclease 1 (FEN1) genotype. Two hundred eighty-eight coke oven male workers were recruited, and we detected the concentration of 1-hydroxypyrene (1-OH-pyr) as PAH exposure biomarker in urine and examined base modification in exons of EGFR and BRCA1 respectively, and genotyped FEN1 rs174538 polymorphism in plasma. We found that the damage indexes of exon 19 and 21 of EGFR (EGFR-19 and EGFR-21) were both significantly associated with increased urinary 1-OH-pyr (both Ptrend < 0.001). The levels of urinary 1-OH-pyr were both significantly associated with increased EGFR-19 and EGFR-21 in both smokers and nonsmokers (both P < 0.001). Additionally, we observed that the urinary 1-OH-pyr concentrations were linearly associated with both EGFR-19 and EGFR-21 only in rs174538 GA+AA genotype carriers (both P < 0.001). Moreover, FEN1rs rs174538 showed modifying effects on the associations of urinary 1-OH-pyr with EGFR-19 and EGFR-21 (both Pinteraction < 0.05). Our findings revealed the linear dose-effect association between exon damage of EGFR and PAH exposure and highlight differences in genetic contributions to exon damage and have the potential to identify at-risk subpopulations who are susceptible to adverse health effects induced by PAH exposure.

  相似文献   
293.
Environmental Science and Pollution Research - In this work, various photocatalysts were synthesized with an impregnation-precipitation process to in situ decorate Ag-based nanoparticles (NPs,...  相似文献   
294.
Environmental Science and Pollution Research - Sugarcane monoculture (SM) often leads to soil problems, like soil acidification, degradation, and soil-borne diseases, which ultimately pose a...  相似文献   
295.
Environmental Science and Pollution Research - There is an increasing number of studies focusing on extreme weather all over the world, but global trends and research topics related to extreme...  相似文献   
296.
Environmental Science and Pollution Research - Metallic glasses (MGs) with unique disordered atomic stacking structures exhibit excellent catalytic performance in wastewater treatment. The...  相似文献   
297.

The Yellow River Delta is the largest and youngest estuarine and coastal wetland in China and is experiencing the most active interactions of seawater and freshwater in the world. Bacteria played multifaceted influence on soil biogeochemical processes, and it was necessary to investigate the intermodulation between the soil factors and bacterial communities. Soil samples were collected at sites with different salinity degree, vegetations, and interference. The sequences of bacilli were tested using 16S rRNA sequencing method and operational taxonomic units were classified with 97% similarity. The soil was highly salinized and oligotrophic, and the wetland was nitrogen-restricted. Redundancy analysis suggested that factors related with seawater erosion were principal to drive the changes of soil bacterial communities and then the nutrient level and human disturbance. A broader implication was that, in the early succession stages of the coastal ecosystem, seawater erosion was the key driver of the variations of marine oligotrophic bacterial communities, while the increasing nutrient availability may enhance in the abundance of the riverine copiotrophs in the late stages. This study provided new insights on the characteristics of soil bacterial communities in estuarine and coastal wetlands.

  相似文献   
298.
Environmental Science and Pollution Research - Soil erosion threatens environmental sustainability worldwide. Exploring the trajectories of soil erosion and associated drivers is of great...  相似文献   
299.
Environmental Science and Pollution Research - Longchun 30, a new wheat variety, was used to investigate seedling growth, element absorption, and antioxidant response under 150 mM NaCl and tea...  相似文献   
300.
Environmental Science and Pollution Research - The high NO2/NOX ratio in the after-treatment system is beneficial to its performance and achieved by NO catalytic conversion in diesel oxidation...  相似文献   
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