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排序方式: 共有218条查询结果,搜索用时 31 毫秒
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Congenital CMV infection (cCMV) is the most prevalent congenital infection, main non-genetic cause of sensorineural hearing loss (SNHL) and major cause of neurological disability. Despite the burden of cCMV, no Public Health body recommends universal serology screening in pregnancy. This was explained by gaps in knowledge of epidemiology, diagnosis, prognosis and the absence of any validated treatment. Over 10 years, progress has been made in our understanding of cCMV following primary maternal infection. Risk factors have been identified and quantified, notably it is now well recognized that among maternal primary infections only those occurring in the first trimester may lead to long-term sequelae. Algorithms combining IgG, IgM, and IgG avidity detection with serological assays adapted on high throughput platforms have demonstrated high sensitivity and specificity to diagnose maternal primary infection. The prognostic value of prenatal imaging combining ultrasound and MRI has been validated by many studies. Finally, recent data from a randomized controlled study demonstrated the efficacy of early antiviral therapy to prevent vertical transmission. Whether CMV serology screening in the first trimester of pregnancy meets the WHO's criteria for a screening program will therefore be reviewed. 相似文献
63.
Different criteria have been proposed for the rapid ecological evaluation of wooded areas. It is difficult, however, to determine the criteria most likely to yield results similar to those that would be obtained through detailed surveys and exhaustive evaluation. In order to identify such synthetic criteria, data from a detailed evaluation of Montreal Urban Community woodlots were studied with the help of multivariate analysis. This detailed evaluation was undertaken at two levels—woodlot unit and the woodlots themselves—using 16 different criteria.At the woodlot unit level, area and abundance indices of shade intolerant species in the tree layer could be used as synthetic criteria, while at the woodlot level the ecological value of the constituent units stand out as the first synthetic criterion. These results are compared with criteria proposed in the literature, and the use of multivariate analysis in ecological evaluation is briefly discussed. 相似文献
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为了解石油工业区土壤中PAHs(多环芳烃)的污染特征、来源及潜在危害,选择兰州市西固区为研究区域,系统采集表层土壤样品及部分剖面样品,采用GC-MS检测方法,分析了土壤中PAHs的污染水平与分布、来源及潜在致癌风险. 结果表明:研究区表层(0~20 cm)土壤中w(∑PAHs)(22种PAHs的总质量分数)在535~32 300 μg/kg之间;PAHs在土壤剖面的纵向分布上主要集中在5~10 cm,在0~25 cm范围内变化不明显;表层土壤中PAHs主要以2~3环为主. 相关性分析显示,土壤中w(∑PAHs)与w(TOC)无显著的相关性,表明TOC并非影响土壤中PAHs持留的重要因素. 研究区土壤中PAHs主要来源于石油、生物质和煤炭的燃烧,∑TEQBaP (22种PAHs的毒性当量浓度,以苯并芘等效浓度计)平均值为190 μg/kg,表明土壤中PAHs的潜在致癌性较低. 相似文献
66.
Gauquelin Thierry Michon Geneviève Joffre Richard Duponnois Robin Génin Didier Fady Bruno Bou Dagher-Kharrat Magda Derridj Arezki Slimani Said Badri Wadi Alifriqui Mohamed Auclair Laurent Simenel Romain Aderghal Mohamed Baudoin Ezekiel Galiana Antoine Prin Yves Sanguin Hervé Fernandez Catherine Baldy Virginie 《Regional Environmental Change》2018,18(3):623-636
Regional Environmental Change - Mediterranean forests are found in the Mediterranean basin, California, the South African Cape Province, South and southwestern Australia and parts of Central Chile.... 相似文献
67.
Ross N. Cuthbert Sven Bacher Tim M. Blackburn Elizabeta Briski Christophe Diagne Jaimie T. A. Dick Franz Essl Piero Genovesi Phillip J. Haubrock Guillaume Latombe Bernd Lenzner Yves Meinard Aníbal Pauchard Petr Pyšek Anthony Ricciardi David M. Richardson James C. Russell Daniel Simberloff Franck Courchamp 《Conservation biology》2020,34(6):1579-1582
Article impact statement: In an era of profound biodiversity crisis, invasion costs, invader impacts, and human agency should not be dismissed. 相似文献
68.
Carolina Gonzalez Merchan Yves Perrodin Sylvie Barraud Christel Sébastian Céline Becouze-Lareure Christine Bazin Gislain Lipeme Kouyi 《Environmental science and pollution research international》2014,21(8):5357-5366
Detention basins are valuable facilities for urban storm water management, from both the standpoint of flood control and the trapping of pollutants. Studies performed on storm water have shown that suspended solids often constitute the main vector of pollutants (heavy metals, polycyclic aromatic hydrocarbon (PAH), etc.). In order to characterise the ecotoxicity of urban sediments from storm water detention basins, the sediments accumulated over a 6-year period were sampled at five different points through the surface of a large detention basin localised in the east of Lyon, France. A specific ecotoxicological test battery was implemented on the solid phase (raw sediment) and the liquid phase (interstitial water of sediments). The results of the study validated the method formulated for the ecotoxicological characterization of urban sediments. They show that the ecotoxicological effect of the sediments over the basin is heterogeneous and greater in areas often flooded. They also show the relationship between, on one hand, the physical and chemical characteristics of the sediments and, on the other hand, their ecotoxicity. Lastly, they contribute to a better understanding of the dynamics of the pollution close to the bottom of detention basins, which can be useful for improving their design. The results of this research raise particularly the issue of using oil separators on the surface of detention basins. 相似文献
69.
Nicolas Picard Steen Magnussen Ludovic Ngok Banak Salomon Namkosserena Yves Yalibanda 《Environmental monitoring and assessment》2010,164(1-4):279-295
Permanent sample plots (PSP), where trees are individually and permanently marked, have received increased interest in Central Africa as a tool to monitor vegetation changes. Although techniques for mounting PSP in tropical forests are well known, their planning still deserves attention. This study aims at defining a rationale for determining the size and number of replicates for setting up PSP in mixed tropical forests. It considers PSP as a sampling plan to estimate a target quantity with its associated margin of error. The target quantity considered here is the stock recovery rate, which is a key parameter for forest management in Central Africa. It is computed separately for each commercial species. The number of trees to monitor for each species defines the margin of error on the stock recovery rate. The size and number of replicated plots is obtained as the solution of an optimization problem that consists in minimizing the margin of error for every species while ensuring that the mounting cost remains below a given threshold. This rationale was applied using the data from the M’Baïki experimental site in the Central African Republic. It showed that the stock recovery rate is a highly variable quantity, and that the typical cost that forest managers are prone to devote to PSP leads to high margins of error. It also showed that the size and number of replicated plots is related to the spatial pattern of trees: clustered or spatially heterogeneous patterns favor many small plots, whereas regular or spatially homogeneous patterns favor few large plots. 相似文献
70.
Marchand G Cloutier Y Pépin C Drolet D 《Journal of environmental monitoring : JEM》2008,10(9):1060-1063
Various counting rules are used for spore trap analysis. Partial count can lead to concentration errors. This paper demonstrates that the number of traverses counted affects the final results. 相似文献