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971.
J. Caspar Rüegg 《Die Naturwissenschaften》1998,85(12):575-582
2+ concentrations tropomyosin is located at the edge of the thin filament, thereby interfering with the formation of strong
actin-myosin linkages (blocked state). An increase in Ca2+ activity causes an azimuthal shift of tropomyosin around the filament (by about 30°), thereby increasing the probability
of low-force crossbridge interaction, a process which by cooperative effects induces further tropomyosin movement (by an additional
10°) which results in the open state of the filament characterized by forceful crossbridge interaction. (This mechanism may
be analogous to that in ligand-gated ion channels, where ligand binding increases the open probability of the pore.) The extent
of activation then depends on the free Ca2+ concentration and on the calcium sensitivity of the thin filament that may be affected by protein phosphorylation, crossbridge
attachment, the troponin isoform composition of the filament, and novel calcium-sensitizing drugs that act on the contractile
or regulatory proteins and thus increase the force of the heart. 相似文献
972.
973.
Kurz Werner A. Beukema Sarah J. Apps Michael J. 《Mitigation and Adaptation Strategies for Global Change》1997,2(4):405-421
Land-use change from an unmanaged to a managed forested landscape in northern forests is associated with a reduction of the
area annually affected by natural disturbances (wildfires and forest insects) and the introduction of harvesting as a new
disturbance. This study examined the impacts of changes in the disturbance regime-the frequency and type of disturbance-on
landscape-level carbon (C) content and fluxes. The Carbon Budget Model of the Canadian Forest Sector was used to assess these
impacts in six representative landscapes (100,000 ha each) with a range of disturbance regimes that are characteristic of
conditions in coastal British Columbia, the interior of British Columbia, and the eastern boreal forest in Canada. The model
was used to simulate ecosystem C fluxes during a period of natural disturbances, a 50-year transition period during which
harvesting replaced natural disturbances, followed by 150 years of harvesting. The initial landscape-level biomass C content
under natural disturbance regimes in the six example landscapes was 22 to 75% of their potential maximum content which is
often used as the reference or baseline case. After 200 years of forest management, the C stored in the landscape plus the
C retained in forest products manufactured from harvested biomass was between 58 and 101% of the landscape C content prior
to the onset of harvesting. Landscape-level ecosystem C content was found to be affected by changes in the disturbance frequency,
the age-dependence of the disturbance probabilities, and the disturbance-specific impacts on ecosystem C content. The results
indicate that using the potential maximum C content of a landscape as the baseline always overestimates the actual C release
due to land use change. A more meaningful procedure would be to assess the actual differences in landscape-level C content
between the natural and the managed disturbance regime. 相似文献
974.
975.
976.
Mitigation and Adaptation Strategies for Global Change - Guidelines of the Intergovernmental Panel on Climate Change (IPCC) were used to assess a greenhouse gas inventory for land use change and... 相似文献
977.
978.
979.
980.
In several branches of science and technology a gaseous phase is dispersed into a liquid in the form of bubbles, a gaseous
component then dissolves into the liquid and subsequently undergoes chemical reaction. The overall process performance can
be improved substantially when the area of gas–liquid contact is increased. By subjecting the liquid phase to low frequency
vibrations, the bubbles are shown to suffer significant breakage, induced by resonance. When the vibration is properly tuned,
the interfacial area is found to increase by a factor of 1.8–2.4, depending on the properties of the liquid. Resonance-induced
bubble breakage phenomena have a great potential for improving the rates of chemical processes involving fast reactions, with
minimal energy input.
Received: 7 July 2000 / Accepted in revised form: 28 August 2000 相似文献