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221.
将离体肝细胞和肝脏S9组分用于获取鱼类的体外生物转化数据可以优化模拟评估对化学物质的生物富集作用。然而涉及2种方式之间的直接对比的研究却几乎没有。本研究采用冷藏保存的鲑鱼肝细胞来测定对于6种多环芳烃(PAHs)的体外本征清除速率。我们运用测定结果推测体内本征清除速率,并将其作为输入值输入一种充分搅匀的肝脏模型中来预测肝清除速率。将事先由体外灌流肝脏测定的速率作为参考来评价预测结果。在2种竞争结合的假说前提下,由鲑鱼肝细胞测出的肝清除速率与实现的测定结果基本一致(6种多环芳烃中的5种都保持在2.1倍差异以下)。尽管多环芳烃的高代谢率是可能的原因之一,这些发现与之前由肝脏S9组分得出的结果相似。对苯并芘这一种化合物而言,由S9数据得出的体内本征清除速率是由肝细胞得出结果的10倍左右,这一结果可能是由细胞吸收速率造成的传播限制引起的。尽管苯并芘的结果差异较大,由任何一种体外测试方法得出的体内本征清除速率结果通常是一致的。这些结果显示离体肝细胞和肝脏S9组分2种系统均可用于优化鱼类的生物富集评估,尤其对于体外反应速率较高的情况。不同系统在化工领域的应用性是否相同则需要进一步的研究工作。
精选自Kellie A. Fay, Patrick N. Fitzsimmons, Alex D. Hoffman, John W. Nichols. Comparison of trout hepatocytes and liver S9 fractions as in vitro models for predicting hepatic clearance in fish. Environmental Toxicology and Chemistry: Volume 36, Issue 2, pages 463–471, July 2017.
DOI: 10.1002/etc.3572
详情请见http://onlinelibrary.wiley.com/wol1/doi/10.1002/etc.3572/full 相似文献
222.
Assessment of Ni accumulation capability by fungi for a possible approach to remove metals from soils and waters 总被引:1,自引:0,他引:1
Grazia Cecchi Enrica Roccotiello Simone Di Piazza Alex Riggi Mauro Giorgio Mariotti 《Journal of environmental science and health. Part. B》2017,52(3):166-170
ABSTRACTAbandoned industrial sites and mines may constitute possible hazards for surrounding environment due to the presence of toxic compounds that may contaminate soils and waters. The possibility to remove metal contaminants, specifically nickel (Ni), by means of fungi was presented exploiting a set of fungal strains isolated from a Ligurian dismissed mine. The achieved results demonstrate the high Ni(II) tolerance, up to 500 mg Ni l?1, and removal capability of a Trichoderma harzianum strain. This latter hyperaccumulates up to 11,000 mg Ni kg?1, suggesting its possible use in a bioremediation protocol able to provide a sustainable reclamation of broad contaminated areas. 相似文献
223.
Under the Canadian Species at Risk Act (SARA), Garry oak (Quercus garryana) ecosystems are listed as “at-risk” and act as an umbrella for over one hundred species that are endangered to some degree.
Understanding Garry oak responses to future climate scenarios at scales relevant to protected area managers is essential to
effectively manage existing protected area networks and to guide the selection of temporally connected migration corridors,
additional protected areas, and to maintain Garry oak populations over the next century. We present Garry oak distribution
scenarios using two random forest models calibrated with down-scaled bioclimatic data for British Columbia, Washington, and
Oregon based on 1961–1990 climate normals. The suitability models are calibrated using either both precipitation and temperature
variables or using only temperature variables. We compare suitability predictions from four General Circulation Models (GCMs)
and present CGCM2 model results under two emissions scenarios. For each GCM and emissions scenario we apply the two Garry
oak suitability models and use the suitability models to determine the extent and temporal connectivity of climatically suitable
Garry oak habitat within protected areas from 2010 to 2099. The suitability models indicate that while 164 km2 of the total protected area network in the region (47,990 km2) contains recorded Garry oak presence, 1635 and 1680 km2 of climatically suitable Garry oak habitat is currently under some form of protection. Of this suitable protected area, only
between 6.6 and 7.3% will be “temporally connected” between 2010 and 2099 based on the CGCM2 model. These results highlight
the need for public and private protected area organizations to work cooperatively in the development of corridors to maintain
temporal connectivity in climatically suitable areas for the future of Garry oak ecosystems. 相似文献
224.
Michael Süß Alex De Visscher 《Journal of the Air & Waste Management Association (1995)》2013,63(9):1107-1115
The occurrence of multiple steady states in a toluene biodegrading, diffusion-limited biofilm under aerobic conditions was investigated by computer models: one steady-state, and one nonsteady-state. Two stable and one unstable intermediate steady-state were identified in a narrow set of combinations of parameters values. The nonsteady-state model predicts conditions that evolve to a steady state that is within 0.02–1% of the solution of the steady-state model, depending on the number of grid points used, confirming the algorithms are valid. Multiple steady states occur if, (1) a biofilm is exposed to a constant gas-phase pollution concentration, which exceeds or undershoots a certain threshold, (2) in a narrow range of parameter values and (3) provided that the pollutant degradation follows Haldane kinetics. Such a biofilm displays half-saturation (i.e., Michaelis-Menten)-like apparent (“falsified”) kinetics from a concentration range starting at zero up to the occurrence of a second steady state. Multiple steady states and falsified kinetics can negatively affect a biofilter and the experimental determination of kinetic parameters, respectively.Implications: The occurrence of multiple steady states in a VOC treating biofilm, shows the significant impact of degradation kinetics and diffusion limitation on the biofilm behavior. Moreover, the implied possible sudden drop of removal efficiency of a biofilter, based on the occurrence of multiple steady states lead to possible bottle-necks in biofilter application and operation. 相似文献
225.
Alex R. Gholson Julia F. Storm R. K. M. Jayanty Robert G. Fuerst Thomas J. Logan M. Rodney Midgett 《Journal of the Air & Waste Management Association (1995)》2013,63(9):1210-1217
Regulation to control air emissions of toxic organic compounds require the collection and analysis of effluent gas from low level sources such as hazardous waste incinerators. The standard SW- 846 Method specifies the use of Tenax and Tenax/charcoal adsorbent traps for collection of volatile organics from incinerators. This study evaluates passivated stainless steel canisters as an alternative to adsorbent traps to eliminate some of the problems associated with adsorbent sampling. Initially the stability of 18 nonpolar, volatile organic compounds was determined in Summa-treated stainless steel canisters with greater than 100 ppmv HCI and saturated with water vapor. All 18 components were stable for a twoweek period; however, an Interference caused a 10-fold increase In the FID response of trlchloroethylene, toluene, and chlorobenzene. No Interference of the ECD response was found for any of the 11 compounds detected with the ECD including trlchloroethylene. A pilot scale incinerator was sampled using canisters, and the destruction efficiency of 1,1,1-trichloroethane was determined at a concentration of less than 0.5 ppbv while determining 1,1-dichloroethylene, the major product of Incomplete combustion, at a concentration of 8000 ppbv from the same sample. 相似文献
226.
Alex Lockwood 《Environmental Communication: A Journal of Nature and Culture》2016,10(6):734-748
ABSTRACTHow can theories of affect and felt emotions be useful in studying the communication of environmental crises? Beginning from tears spilt over a graph of transgressed planetary boundaries published in an academic paper, this article explores the presentation in graphic visual forms of affective imagery and a growing sophistication amongst scientists, policymakers and activist communicators in the visualization of information, data and stories employed to carry the often difficult and complex messages of current earth systems crises. Critically, this article attends to the “emotion work” of such images. Taking a lead from cultural sociology and attempting to elucidate the relationship between societies under pressure and its choice of texts, this article considers the environmental documentary Cowspiracy [Anderson, K., & Kuhn, K. (2014). Cowspiracy. San Francisco, CA: AUM Films & First Spark Media.] to ask questions of affect’s relation to expressions of the earth systems crisis, which is also a crisis of culture. 相似文献
227.
228.
Alberto Acerbi John Burns Unal Cabuk Jakub Kryczka Bethany Trapp John Joseph Valletta Alex Mesoudi 《Conservation biology》2023,37(4):e14060
The role of nature documentaries in shaping public attitudes and behavior toward conservation and wildlife issues is unclear. We analyzed the emotional content of over 2 million tweets related to Our Planet, a major nature documentary released on Netflix, with dictionary and rule-based automatic sentiment analysis. We also compared the sentiment associated with species mentioned in Our Planet and a set of control species with similar features but not mentioned in the documentary. Tweets were largely negative in sentiment at the time of release of the series. This effect was primarily linked to the highly skewed distributions of retweets and, in particular, to a single negatively valenced and massively retweeted tweet (>150,000 retweets). Species mentioned in Our Planet were associated with more negative sentiment than the control species, and this effect coincided with a short period following the airing of the series. Our results are consistent with a general negativity bias in cultural transmission and document the difficulty of evoking positive sentiment, on social media and elsewhere, in response to environmental problems. 相似文献
229.
Spatial Analysis of Soil Salinity and Soil Structural Stability in a Semiarid Region of New South Wales,Australia 总被引:3,自引:0,他引:3
Salt-affected soils are a major threat to agriculture especially in the semiarid regions of the world. The effective management of these soils requires adequate understanding of not only how water and, hence, solutes are transported within the soil, but also how soil salinity and sodicity spatially interact to determine soil structural breakdown. For sustainable agricultural production, information on quantitative soil quality, such as salinity, is required for effective land management and environmental planning. In this study, quantitative methods for mapping indicators of soil structural stability, namely salinity and sodicity, were developed to assess the effect of these primary indicators on soil structural breakdown. The current levels of soil salinity, as measured by electrical conductivity (EC) of the soil/water suspension, soil sodicity, represented by exchangeable sodium percentage (ESP), and aggregate stability, were assessed. Remote sensing, geographical information system (GIS), and geostatistical techniques-primarily regression-kriging and indicator-kriging-were used to spatially predict the soil sodicity and salinity. The patterns of salinity (EC) and sodicity (ESP > 5%) were identified. The effect of land use on these soil quality indicators was found to be minimal. Co-spatial patterns were elucidated between sodic soils (defined by ESP > 5%) and highly probable mechanically dispersive soils predicted from indicator-kriging of ASWAT scores. It was established that the incorporation of EC with ESP into an objective index, called electrolyte stability index (ESI = ESP/EC), gave a good indication of soil dispersion, although the threshold ESI value below which effective structural breakdown might occur is 0.025, which is twice as small as the expected 0.05. The discrepancies between ESI and ASWAT scores suggest that other soil factors than salinity and sodicity are affecting soil structural breakdown. This calls for further investigation. The study provides valuable information in the form of risk zones of soil structural breakdown for land management. These zones, with a probability of mechanical soil dispersion of >0.70, require immediate management attention with greater monitoring and amelioration techniques, particularly gypsum or lime application and/or altered cultivation techniques. 相似文献
230.
Acuña Guillermo Ignacio Echeverría Cristián Godoy Alex Vásquez Felipe 《Environmental Economics and Policy Studies》2020,22(1):89-108
Environmental Economics and Policy Studies - This paper analyses the existence of convergence in residential water consumption across geographical regions using econometric methods taken from the... 相似文献