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11.
In the present study, we have investigated the influence of polymorphism of GSTM1 and GSTT1 genes and confounding factors such as age, sex, exposure duration and consumption habits on cytogenetic biomarkers. Frequency of sister chromatid exchanges (SCEs), high frequency cell (HFC) and cytokinesis blocked micronuclei (CBMN) were evaluated in peripheral blood lymphocytes of 115 occupationally exposed road construction workers and 105 unexposed individuals. The distribution of null and positive genotypes of glutathione-S transferase gene was evaluated by multiplex PCR among control and exposed subjects. An increased frequency of CBMN (7.03 ± 2.08); SCE (6.95 ± 1.76) and HFC (6.28 ± 1.69) were found in exposed subjects when compared to referent (CBMN - 3.35 ± 1.10; SCE - 4.13 ± 1.30 and HFC - 3.98 ± 1.56). These results were found statistically significant at p < 0.05. When the effect of confounding factors on the frequency of studied biomarkers was evaluated, a strong positive interaction was found. The individuals having GSTM1 and GSTT1 null genotypes had higher frequency of CBMN, SCE and HFC. The association between GSTM1 and GSTT1 genotypes and studied biomarkers was found statistically significant at p < 0.05. Our findings suggest that individuals having null type of GST are more susceptible to cytogenetic damage by occupational exposure regardless of confounding factors. There is a significant effect of polymorphism of these genes on cytogenetic biomarkers which are considered as early effects of genotoxic carcinogens. 相似文献
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Anita Lewandowska Lucyna Falkowska Joanna Jóźwik 《Environmental science and pollution research international》2013,20(9):6109-6118
Fluoride concentrations were determined in PM10 samples collected in the urbanized coastal area of the Baltic Sea (Gdynia) in the period between 1 August 2008 and 8 January 2010. F? concentrations remained within the range of 0.4–36.6 ng?·?m?3. The economic transformations which have taken place in Poland increasing ecological awareness have had an excellent effect on the levels of fluoride pollution in the air of the studied region. In our measurements, fluoride concentrations increased in wintertime, when air temperature dropped, at low wind speeds (<1 m?·?s?1) and with low dispersion of pollutants originating from local sources (traffic, industry, domestic heating). At times when wind speed grew to >10 m?·?s?1, fluorides were related to marine aerosols or else brought from distant sources. Apart from wind speed and air temperature, other significant meteorological parameters which determined the variability of F? turned out to be air humidity and precipitation volume. Aerosols were washed out effectively, even with small precipitation (h?=?4 mm), and if a dry period lasted for several days, their concentrations grew rapidly to over 30.0 ng?·?m?3. 相似文献
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Veihe A 《Environmental management》2000,25(4):393-402
/ Major responsibility for conserving forest biodiversity is often assigned to natural resource agencies. Often unknown is the appropriate administrative context for doing so, especially the organizational location for biodiversity programs in state government, suitable levels of financial and professional investment in biodiversity programs, processes useful for coordinating programs located in different administrative settings, and the effectiveness of biodiversity programs, especially conditions associated with programs judged to be very effective. Focusing on forests, a nationwide survey of 156 forestry agency and biodiversity program administrators in all 50 states was undertaken. Effective forest biodiversity programs were those with a long-range plan, administered as a single organizational unit, located in close organizational proximity to a state's forestry agency, actively providing management practice advice to landowners, administrators, and the public, and firm actions taken to ensure coordination with other natural resource programs. 相似文献
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Jürgen Weber Anita Plantikow und Jupp Kreutzmann 《Umweltwissenschaften und Schadstoff-Forschung》2000,12(4):185-189
Zusammenfassung Die G?rleistung der HefeSaccharomyces cerevisiae wird als Bioindikator zur Erfassung aquatoxischer Wirkungen genutzt. Dazu wird die CO2-Produktion der Hefezellen nach einer Vermehrungsphase unter toxischen Einflüssen gemessen. Als Kennwert (EC20) dient die Schadstoffkonzentration, die die G?rung um 20% mindert. Es werden organische Verbindungen (unpolare und polare
Narkotika), anorganische Salze (insbesondere von Schwermetallen), Tenside und Pflanzenschutzmittel geprüft. Die Ergebnisse
werden, soweit verfügbar, mit den Daten eines Ciliatentestes mitTetrahymena pyriformis verglichen. Es ergab sich eine übereinstimmung von 90% bei vergleichbarer Testempfindlichkeit. Ergebnisse des Hefetests sind
damit ?kotoxikologisch aussagef?hig. Der Test ist reproduzierbar, methodisch einfach zu handhaben und bietet eine Alternative
für die Abwasserprüfung, da steriles Arbeiten nicht erforderlich ist.
Online-First: 15. Juni 2000 相似文献
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Anita K. Lindsey Thomas M. Walski 《Journal of the American Water Resources Association》1982,18(2):331-334
ABSTRACT: The cost of sanitary facilities is a major cost item in recreation areas at water resources projects. Often planners wish to analyze the tradeoffs in providing different levels of service at these areas. Cost functions are presented in this paper to enable the planner to make quick comparisons between different types of buildings, sizes, exterior treatments, and number of fixtures. 相似文献
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Anita R. Freudenthal 《Chemistry and Ecology》1998,15(1):199-209
The Rapid Sewage/Sludge Indicator Technique (RSIT), developed during the early 1970's, responded to critical needs within the Bureau of Water Pollution Control. It enabled quick detection of contamination in ocean water and bottom sediments during sewage-related emergencies and routine monitoring. RSIT became an invaluable tool for resource management, in determining where and to what extent marine environments are impacted, and when immediate information is necessary for public health decisions.
The RSIT utilizes microscopic examination for terrestrial plant vascular tissue, especially the xylem tracheid elements, as identifiers of sewage/sludge. Not normally found in ocean waters, this material, in toilet paper and the roughage of the human diet which passes through the digestive system intact, is an indicator of human faecal contamination. Minimal training and common laboratory materials allow gross screening in five minutes. New studies by the United States Environmental Protection Agency (USEPA), United States Geologic Survey (USGS) and National Oceanic and Atmospheric Administration (NOAA), most recently at the 106-mile dump site off the New York Bight, revalidated the technique as a rapid, inexpensive, easy to use, semiquantitative indicator both for water column and sediment samples. 相似文献
The RSIT utilizes microscopic examination for terrestrial plant vascular tissue, especially the xylem tracheid elements, as identifiers of sewage/sludge. Not normally found in ocean waters, this material, in toilet paper and the roughage of the human diet which passes through the digestive system intact, is an indicator of human faecal contamination. Minimal training and common laboratory materials allow gross screening in five minutes. New studies by the United States Environmental Protection Agency (USEPA), United States Geologic Survey (USGS) and National Oceanic and Atmospheric Administration (NOAA), most recently at the 106-mile dump site off the New York Bight, revalidated the technique as a rapid, inexpensive, easy to use, semiquantitative indicator both for water column and sediment samples. 相似文献
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Perceived prosocial impact,perceived situational constraints,and proactive work behavior: Looking at two distinct affective pathways
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This paper examines the role of affect as a linking mechanism between experiences at work (perceived prosocial impact and situational constraints) and two distinct components of proactive work behavior (issue identification and implementation). Based on a dual‐tuning perspective, we argue that both positive affect and negative affect can be beneficial for proactive work behavior. Multi‐level path analysis using daily‐survey data from 153 employees showed that perceived prosocial impact predicted positive affect and that situational constraints as a typical hindrance stressor predicted negative affect. Negative affect, in turn, predicted issue identification, and positive affect predicted implementation. Overall, our study suggests that both positive and negative affects can be valuable in the organizational context by contributing to distinct components of proactive behavior. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献