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Congenital nephrotic syndrome with ventriculomegaly and a normal karyotype is a rare association. We report four cases, three of which were conceived consecutively by one couple. All the cases were associated with elevated maternal serum alpha-fetoprotein. Renal histology in one fetus demonstrated colloid filled cysts distributed in the corticomedullary area. Transmission electron microscopy of the glomeruli showed normally developed foot processes and confirmatory genetic studies excluded Finnish congenital nephrotic syndrome. It is probable that congenital nephropathy in conjunction with ventriculomegaly is the result of an autosomal recessive syndrome. Copyright © 2002 John Wiley & Sons, Ltd. 相似文献
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Male-biased predation of a cave fish by a giant water bug 总被引:1,自引:0,他引:1
Male-biased predation has been described from several epigean species, and in many cases, intrinsic differences between the sexes (such as male ornaments) have been suggested as an explanation. Here we report on male-biased predation of a cave fish (Poecilia mexicana) by an aquatic insect (Belostoma sp.) in a Mexican sulfur cave. P. mexicana use aquatic surface respiration (ASR) to survive in their sulfidic, hypoxic habitat. We found that males typically exhibit more ASR activity than females, which leads to increased exposure to the sit-and-wait predator that catches fish near the water surface. Our finding is novel, because male vulnerability to predation is not directly related to male traits involved in courtship, but rather due to other sexual differences in behavior and ultimately, oxygen demands. 相似文献
105.
Richard W. McDowell Ton SnelderRoger Littlejohn Matt HickeyNeil Cox Doug J. Booker 《Agriculture, ecosystems & environment》2011,144(1):188-200
Land use change and the expansion of dairying are perceived as the cause of poor water quality in the 1881 km2 Pomahaka catchment in Otago, New Zealand. A study was conducted to determine the long-term trend at four sites, and current state in 13 sub-catchments, of water quality. Drains in 2 dairy-farmed sub-catchments were also sampled to determine their potential as a point source of stream contamination. Data highlighted an overall increase in the concentration of phosphorus (P) fractions at long-term sites. Loads of contaminants (nitrogen (N) and P fractions, sediment and Escherichia coli) were greatest in those sub-catchments with the most dairying. Baseline (without human influence) contaminant concentrations suggested that there was considerable scope for decreasing losses. At most sites, baseline concentrations were <20% of current median concentrations. Contaminant losses via drainage were recorded despite there being no rainfall that day and attributed to applying too much effluent onto wet soil. Modelling of P concentrations in one dairy-farmed sub-catchment suggested that up to 58% of P losses came from point sources, like bad effluent practice and stock access to streams. A statistical test to detect “contaminated” drainage was developed from historical data. If this test had been applied to remove contaminated drainage from samples of the two dairy-farmed sub-catchments, median contaminant concentrations and loads would have decreased by up to 58% (greater decreases were found for E. coli, ammoniacal-N and total P than other contaminants). This suggests that better uptake of strategies to mitigate contamination, such as deferred effluent irrigation (and low rate application), could decrease drainage losses from dairy-farmed land and thereby improve water quality in the Pomahaka catchment. 相似文献
106.
Rebecca L. Hale Courtney G. Flint Douglas Jackson‐Smith Joanna Endter‐Wada 《Journal of the American Water Resources Association》2018,54(5):1137-1150
With growing urban populations and climate change, urban flooding is an important global issue, even in dryland regions. Flood risk assessments are usually used to identify vulnerable locations and populations, flooding experience patterns, or levels of concern about flooding, but rarely are all of these approaches combined. Furthermore, the social dynamics of flood concerns, exposure, and experience are underexplored. We combined geographic and survey data on household‐level measures of flood experience, concern, and exposure in Utah's urbanizing Wasatch Front. We asked: (1) Are socially vulnerable groups more likely to be exposed to flood risk? (2) How common are flooding experiences among urban residents, and how are these experiences related to sociodemographic characteristics and exposure? and (3) How concerned are urban residents about flooding, and does concern vary by exposure, flood experience, and sociodemographic characteristics? Although floodplain residents were more likely to be White and have higher incomes, respondents who were of a racial/ethnic minority, were older, had less education, and were living in floodplains were more likely to report flood experiences and concern about flooding. Flood risk management approaches need to address social as well as physical sources of vulnerability to floods and recognize social sources of variation in flood experiences and concern. 相似文献
107.
Courtney E. Moore Steven P. Loheide II Christopher S. Lowry Jessica D. Lundquist 《Journal of the American Water Resources Association》2014,50(4):1033-1050
Vegetation in subalpine meadows in the Sierra Nevada Mountains is particularly vulnerable to lowering of groundwater levels because wet meadow vegetation is reliant upon shallow groundwater during the dry summer growing season. These ecosystems are especially vulnerable to channel incision as meadow aquifers are hydrologically connected to tributaries, and many have not yet recovered from previous anthropogenic influences. While instream restoration projects have become a common approach, lack of postrestoration monitoring and communication often result in a trial‐and‐error approach. In this study we demonstrate that preimplementation modeling of possible instream restoration solutions, chosen to raise stream stage and subsequently groundwater levels, is a useful tool for evaluating and comparing potential channel modifications. Modeling allows us to identify strategic locations and specific methods. Results show additional sediment depth and roughness on tributaries along with introduced woody debris (simulated by high roughness) on the Tuolumne River are the most effective means of raising stream stage. Results demonstrate that restoration efforts are most efficient in tributary streams. Managers and planners can more efficiently direct resources while minimizing the potential for negative impacts or failed restoration projects by modeling the possible effects of multiple restoration scenarios before implementation. 相似文献
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109.
In order to assist an integrated development of ionic liquids (ILs), a study on the sorption, distribution, and cytotoxicity of a series of 1-alkyl-3-methyl imidazolium tetrafluoroborates with C6 rat glioma cells has been performed. Cellular sorption and distribution among three cellular fractions (cytosol, nuclei, and membranes) were analysed by reversed-phase HPLC (RP-HPLC). Compounds with longer 1-alkyl substituents were sorbed with higher enrichment factors and sorption coefficients per protein than those with shorter 1-alkyl chains. The 1-octyl-3-methyl imidazolium cation (C8MIM) was enriched 17-folds whereas C6MIM and C4MIM were enriched by factors of 3.5 and 2.3, respectively. After fractionation of cells by centrifugation, about 8% of C8MIM was found in the nuclear fractions. The cytotoxicity as estimated by the tetrazolium reductase assay was increasing with the lengths of the 1-alkyl chains from C4MIM to C10MIM. Consistently, cell proliferation rates were decreasing with increasing lengths of the 1-alkyl chains. The results reveal the correlations between lipophilicity, cellular sorption, and cytotoxicity. 相似文献
110.