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排序方式: 共有166条查询结果,搜索用时 15 毫秒
61.
Laurence Michel-Calemard Gaëtan Lesca Yves Morel Dominique Boggio Henri Plauchu Jocelyne Attia-Sobol 《黑龙江环境通报》2004,24(7):519-523
This is the first report of a fetus affected with campomelic acampomelic dysplasia presenting with increased nuchal translucency. Ultrasonography at 13 weeks of amenorrhea showed a nuchal translucency 5.6 mm thick. The karyotype performed on amniotic fluid cells was normal (46,XY). Ultrasonography at 22 weeks revealed a normal femoral length and female genitalia. A second amniocentesis was performed to confirm the karyotype and for dosage of steroid hormones. Testosterone dosage was low, corresponding to a female fetus. Ultrasonography at 32 weeks showed growth retardation of the long bones (<3rd centile) that were not curved. A severe malformation syndrome was suspected and the pregnancy was terminated at 33 weeks. The fetus displayed macrocephaly, facial dysmorphism and female external genitalia. X ray showed straight and thickened long bones, hypoplastic scapulae and moderate platyspondyly. In view of the association of sex reversal, hypoplasia of the scapulae, and the presence of straight long bones, campomelic acampomelic dysplasia was suspected and confirmed by the finding of a SOX9 mutation. This case shows the importance of a careful echographic survey in a fetus with a nuchal translucency > 4 mm, especially if there is discordance between phenotypic and genotypic sex, since growth retardation may occur later during the pregnancy. Copyright © 2004 John Wiley & Sons, Ltd. 相似文献
62.
Jean-Luc Volumenie Pascal de Lagausie Jean Guibourdenche Jean-François Oury Edith Vuillard Carole Saizou Dominique Luton 《黑龙江环境通报》2001,21(13):1171-1174
This study aimed to analyse the influence of amnio-infusion on superior mesenteric Doppler velocimetry and to correlate Doppler data with outcome in fetuses presenting with gastroschisis. Umbilical and intra- and extra-abdominal superior mesenteric artery Doppler velocimetry was measured prospectively before and after amnio-infusion in fetuses with gastroschisis. Doppler index values and changes were correlated with the following outcome parameters: importance of fibrous coating, duration of hospitalization in the neonatal intensive care unit, total duration of hospitalization, duration of parenteral feeding, duration of ventilatory assistance, and the interval to initiation of oral feeding. A significant improvement of diastolic flow was observed in the extra-abdominal superior mesenteric artery with amnio-infusion. No similar change was seen in the intra-abdominal superior mesenteric or in the umbilical artery. Pre-amnioinfusion extra-abdominal mesenteric Doppler index was correlated with maximal diameter of exteriorized bowel and slightly with duration of hospitalization in the neonatal intensive care unit, but no other relation between Doppler index and outcome parameter could be ascertained. Amnio-infusion induces modifications in the vascularization of exteriorized bowel in gastroschisis. This could partly explain the beneficial effect of this procedure on fetal gut. Copyright © 2001 John Wiley & Sons, Ltd. 相似文献
63.
Jakobsen L Sandvang D Hansen LH Bagger-Skjøt L Westh H Jørgensen C Hansen DS Pedersen BM Monnet DL Frimodt-Møller N Sørensen SJ Hammerum AM 《Environment international》2008,34(1):108-115
The aim of the study was to investigate the potential spread of gentamicin resistant (GEN(R)) Escherichia coli isolates or GEN(R) determinants from a Danish university hospital to the waste water environment. Waste water samples were collected monthly from the outlets of the hospital bed wards and the inlet of the related waste water treatment plant (WWTP) from October 2002 to August 2003. Waste water samples were also collected monthly from a residential area in the same period to be able to compare the prevalence of GEN(R)E. coli isolates from hospital related and residential waste water. The waste water isolates were compared to GEN(R)E. coli isolates obtained consecutively from September 2002 to September 2003 from patients mainly with urinary tract infections at the hospital with respect to Pulsed Field Gel Electrophoresis (PFGE) profiles. All isolates were investigated for GEN(R) mechanisms (aac(3)-II, aac(3)-IV, ant(2')-I, armA), phenotypic resistance pattern, and virulence genes (hlyA, chuA, sfaS, fogG, malX, traT, iutA, fyuA, iroN, cnf1) to investigate if the hospital and waste water could be reservoirs of antimicrobial resistance and virulence. The ability for GEN(R) determinants to transfer horizontally was investigated by mating experiments. A total of 38, 15, 21, and two GEN(R)E. coli were isolated from patients, the hospital outlets, the inlet of the WWTP, and the residential area, respectively. GEN(R)E. coli were more prevalent in waste water from the hospital and the WWTP than in waste water from the residential area. PFGE profiling revealed no spread of specific patient isolates to the waste water. The aac(3)-II gene was detected both in patient and waste water isolates. Furthermore horizontal transfer of the aac(3)-II gene of patient origin to a recipient was shown in vitro, indicating a potential spread of the gene from patient isolates to waste water isolates. Regardless of origin, most isolates exhibited multi-resistance and contained several virulence genes. In conclusion, our study showed a possible spread of aac(3)-II from the hospital to the waste water. Most of the GEN(R)E. coli isolates from both patients and waste water had a multi-resistant phenotype and contained virulence genes and should therefore be considered reservoirs of antimicrobial resistance and virulence genes. 相似文献
64.
65.
Hora RR Ionescu-Hirsh A Simon T Delabie J Robert J Fresneau D Hefetz A 《Die Naturwissenschaften》2008,95(1):55-60
In the ectatommine ant Ectatomma tuberculatum, the visual appearance of queens changes after mating and ovarian development in that their cuticle turns from shiny to matte.
In this study, we have shown that this change seems to be caused by 15-fold accumulation of hydrocarbons, in particular heptacosane
that covers the multiple grooves present on the cuticular surface creating a wax coat in mated fully fertile queens. Analyses
of the scrapped wax revealed that it is composed largely of heptacosane. Peak-by-peak comparison of the cuticular hydrocarbon
(CHC) composition of mated, virgin with developed ovaries and virgin with nondeveloped ovaries revealed significant differences
between the queen groups. Although the total amount of the CHC of virgin queens with developed ovaries was not higher than
virgin queens that did not have developed ovaries, the composition showed a shift toward the mated queen. While it is possible
that the large accumulation of hydrocarbons may give extra physical and chemical protection to queens, we propose that the
switch in the relative abundance of heptacosane and nonacosane and perhaps of other components is indicative of being a mating
and fertility cue. This is the first report in social insects where external chemical changes are accompanied by changes in
visual appearance. 相似文献
66.
BACKGROUND: The ability for suicides of drivers to be disguised as traffic accidents raises the possibility that suicidal behaviors of this nature are far more prevalent than previously thought, potentially impacting health, road safety, and insurance companies. METHOD: Persons residing at the Gold Coast, Australia, identified as having a history of suicidal ideation and behaviors (n = 1,196), were sent a mail-out survey after their consent was obtained in initial telephone contact (CATI random digit-dialing). Among those responding, 412 had made suicide plans or arrangements and 228 suicide attempts. RESULTS: Of those who reported planning a suicide, 14.8% (19.1% of male planners and 11.8% of female planners) had conceived to have a motor vehicle "accident" (n = 61). Of all attempters, 8.3% (13.3% of male attempters) had previously attempted via motor vehicle collision (n = 19). All attempters reported having emotional or mental problems at the time of the event. Suicide planners were significantly more likely to be in full-time employment and have a partner and children compared with other planners. CONCLUSION: The study gives a rare insight into driver suicide plans and attempts, via a large-scale community survey, to provide the best opportunity of collecting unbiased data on the driver suicide behavior. Results suggest the use of this method, particularly in attempts made by males, may be underreported leading to inaccuracy of statistics. The motives behind choosing this method are somewhat different to those behind other methods, including financial benefits and eliminating stigma in the aftermath of a suicide. 相似文献
67.
Sauphanor B Franck P Lasnier T Toubon JF Beslay D Boivin T Bouvier JC Renou M 《Die Naturwissenschaften》2007,94(6):449-458
The behavioral and electroantennographic responses of Cydia pomonella (L.) to the ripe pear volatile ethyl (2E,4Z)-2,4-decadienoate (Et-E,Z-DD), were compared in insecticide-susceptible and -resistant populations originating from southern France. A dose–response
relationship to this kairomonal attractant was established for antennal activity and did not reveal differences between susceptible
and resistant strains. Conversely, males of the laboratory strains expressing metabolic [cytochrome P450-dependent mixed-function
oxidases (mfo)] or physiological (kdr-type mutation of the sodium-channel gene) resistance mechanisms exhibited a significantly
higher response to Et-E,Z-DD than those of the susceptible strain in a wind tunnel experiment. No response of the females to this kairomone could be
obtained in our wind-tunnel conditions. In apple orchards, mfo-resistant male moths were captured at significantly higher
rates in kairomone-baited traps than in traps baited with the sex pheromone of C. pomonella. Such a differential phenomenon was not verified for the kdr-resistant insects, which exhibited a similar response to both
the sex pheromone and the kairomonal attractant in apple orchards. Considering the widespread distribution of metabolic resistance
in European populations of C. pomonella and the enhanced behavioral response to Et-E,Z-DD in resistant moths, the development of control measures based on this kairomonal compound would be of great interest for
the management of insecticide resistance in this species. 相似文献
68.
Lucey JA Vintró LL Boust D Mitchell PI Gouzy A Bowden L 《Journal of environmental radioactivity》2007,93(2):63-73
Sequential extraction has been used extensively to study the solid partitioning of radionuclides in soils and sediments. A difficulty with sequential extraction is that radionuclides released by a particular extractant can be resorbed and artificially redistributed amongst the remaining solid phases. Here, we describe experiments (on selected model phase and natural materials), which were designed to determine whether the inclusion of a chelating agent (sodium citrate) in an established sequential extraction protocol (a) inhibits post-extraction resorption of plutonium, (b) increases non-targeted dissolution of sediment phases, and (c) gives rise to unwanted ligand competition for plutonium. The results clearly demonstrate the capacity of citrate to inhibit the resorption of plutonium from the various extractants, and confirm that there is no discernible increase in non-targeted phase dissolution, but indicate significant ligand competition with the carbonate phase. The merits of using citrate are discussed and an optimised sequential extraction protocol that includes citrate is proposed. Finally, the protocol is applied to oxic and anoxic sediments sampled in the NE Irish Sea and the Roads of Cherbourg, and it is shown that the bulk of the plutonium on these sediments is associated with the more labile geochemical fractions. 相似文献
69.
Gaspard Delebecq Dominique Davoult Dominique Menu Marie-Andrée Janquin Jean-Claude Dauvin François Gevaert 《Marine Biology》2013,160(3):503-517
Two populations of Laminaria digitata (Hudson) Lamouroux (Ann Mus Hist Nat Paris 20:21–47, 1813) were examined for their seasonal photosynthetic acclimation to clear and turbid-light environments along the French coast of the English Channel. Photosynthesis–irradiance curves, pigment concentrations and the daily in situ integrated oxygen production rates were measured in both populations. Despite the great differences in light attenuation between the sites, the two populations achieved similar oxygen production rates in the field, in relation to high maximal photosynthetic rates, total pigment concentrations and antenna (fucoxanthin + chlorophyll c)/chl a pigment ratios in sporophytes from the turbid environment. Environmental conditions (i.e. light, temperature and nitrogen availability) changed throughout the year in both sites. While the seasonal acclimation trends were evident in the clear-light environment, the strategy in the turbid-light environment differed, tending to maximize light capture throughout the year. This study highlights the diversity of the response of a single species to contrasted light environments. 相似文献
70.
Olivier Ubrich Balasubrahmanyan Srinivasan Pablo Lerena Dominique Bonvin Francis Stoessel 《Journal of Loss Prevention in the Process Industries》1999,12(6):814-493
Maximising the yield of the second order reaction (2-butanol+propionic anhydride) by manipulating the inlet flow rate is considered for an isothermal semi-batch process. First a procedure for the determination of the kinetic parameters using coupled spectroscopic and calorimetric methods is presented. Then an optimisation of the reaction system is performed numerically and verified experimentally. Constraints on the amount of heat produced and on the temperature attainable in the case of cooling failure are imposed for safety consideration. 相似文献