Effect of Sodium Chloride,Sodium Nitrite and Sodium Nitrate on the Infectivity of Hepatitis E Virus

Food and Environmental Virology - Hepatitis E virus (HEV) infection can cause acute and chronic hepatitis in humans. The zoonotic HEV genotype 3, which is highly prevalent in Europe, is mainly...     

Evolution, radiation and chemotaxonomy of Lamellodysidea, a demosponge genus with anti-plasmodial metabolites

Sponges of the family Dysideidae (Dictyoceratida) are renowned for their diversity of secondary metabolites, and its genus Lamellodysidea, particularly Lamellodysidea herbacea, is the most studied taxon biochemically. Despite its importance, the taxonomic status of L. herbacea—whether it is a distinct species or a species complex—has never been assessed. Recent biochemical profiling revealed anti-plasmodial activity of brominated compounds in Lamellodysidea of the Pacific. Here, we present a comparative chemotaxonomic and molecular analysis of selected Dysideidae from the Pacific and the Indian Ocean (New Caledonia, Great Barrier Reef, Fiji, Mayotte, Guam, Palau). We investigated the phylogenetic relationships between the populations and assessed their bioactive (PBDE) compounds in order to unravel the taxonomic status of this commercially important group of sponges and assessed patterns of dispersal and biochemical variation. The molecular phylogeny was based on the internal transcribed ribosomal spacer and compared against a PBDE phylogeny for several specimens. Molecular data revealed a diversity of Indo-Pacific L. herbacea populations, also reflected by different PBDE compound profiles. Molecular and biochemical data also revealed a Lamellodysidea species new to science. Several specimens misidentified as Lamellodysidea were detected based on their position on different clades in the molecular phylogeny and their production of different halogenated compounds (brominated vs. chlorinated). The direct comparison of molecular and biochemical data also provided evidence for the occurrence of a host switch event and support for the theory that abiotic factors, such as sedimentation, affect the chemical constituents produced in L. herbacea.     

Suspended particulate matter dynamics in a particle framework

Suspended particulate matter (SPM) dynamics in ocean models are usually treated with an advection–diffusion equation for one or more sediment size classes coupled to the hydrodynamical part of the model. Numerical solution of these additional partial differential equations unavoidably introduces numerical diffusion, i.e. in the case of sharp gradients the possible occurrence of artificial oscillations and non-positivity. A Lagrangian particle-tracking model has been developed to simulate short-term SPM dynamics. Modelling individual sediment particles allows a straightforward physical interpretation of the processes. The tracking of large numbers of individual and independent particles (up to 25 million in total in a single sediment class) can be achieved on high performance computer clusters, due to efficient parallelisation of particle tracking. The movement of the particles is described by a stochastic differential equation, which is consistent with the advection–diffusion equation. Here, the concentration profile is represented by a set of independent moving particles, which are advected according to the 3D velocity field, while the diffusive displacements of the particles are sampled from a random distribution, which is related to the eddy diffusivity field. To account for erosion a new parameterisation is proposed. Three numerical particle tracking schemes (EULER, MILSTEIN and HEUN) are presented and validated in idealised test cases. Finally, the particle tracking algorithms are applied to a realistic scenario, a severe winter storm in the East Frisian Wadden Sea (southern North Sea). The comparison with observations and an Eulerian SPM transport model seems to indicate a somewhat better fidelity of the Lagrangian approach.     

Pharmaceutical compound removal efficiency by a small constructed wetland located in south Brazil

Environmental Science and Pollution Research - The fate of pharmaceuticals during the treatment of effluents is of major concern since they are not completely degraded and because of their...     

Air pollution and urban road transport: evidence from the world’s largest low-emission zone in London

Environmental Economics and Policy Studies - Low-emission zones (LEZs) have been implemented widely in Europe to tackle air pollution sourced from vehicular emissions. We quantify the effectiveness...