The development of a method to determine the burden of climate change on different health outcomes at a local scale: a case study in Osaka Prefecture,Japan

Climate change impacts human health in a variety of ways. Variables including the climate-related risk factor, the health outcome and location all determine the nature and extent of the impact. The existence of different pathways and endpoints presents a problem for quantifying and comparing impacts. Disability-adjusted life year (DALY) provides a common scale, whereby the impact of climate change on both acute and chronic health outcomes can be compared. This study presents a methodology to calculate the impact of climate change on human health at a local scale, using cardiovascular disease (CVD) and meteorological disaster-related injuries (DRIs) in Osaka Prefecture, Japan, as applied case studies. An additional very fine scale assessment of CVD conducted at the neighbourhood level to demonstrate the importance of conducting risk assessments at a local level. The comparative results calculated the impact of climate change in 2050 to be 16.866 DALY/100,000 population for CVD and 0.645 DALY/100,000 for meteorological DRIs. The actual impact of climate change by 2050 on CVD is judged to be higher, although the relative risk was projected to be lower (1.006, compared to 1.263 for meteorological DRIs). The fine scale assessment revealed the variations in the projected impact of climate change on CVD for all administrative zones in Osaka Prefecture. The range of impacts varied from 0 to 114.29 DALY/100,000. The results demonstrate the applicability of using DALY to quantify the impact of climate change on different health outcomes, using a transferable methodology, and provide information that enables evidence-based prioritisation of climate change adaptation strategies at a local scale.     

Recovering Food Commons in Post Industrial Europe: Cooperation Networks in Organic Food Provisioning in Catalonia and Norway

This paper explores food commoning through an ethnographic case study in Catalonia as our primary site while the Norwegian case is juxtaposed as a comparison, two agriculturally and economically different European countries. The ethnography analyses cooperation networks between organic food producers’ and consumers’ involving different nodes of community gardening initiatives, self-employed growers, local farmers and all of them under a unique cooperative integrating a community economy. The result it is a myriad of exchange practices ranging from reciprocity and barter to market exchange without intermediaries through on-line platforms. Along these exchanges different options of currency intervene giving rise to novel social and cooperative relations. Similar initiatives in Norway show less variation and are less experimental regarding forms of payment but share similarities in relation to material articulations, concerns and forms of alternative practice. Although these novel forms do not represent a complete break from the more standardized supply chains, and hence from the oppositions/contradictions of production and consumption, the participants see themselves as contributing to a more general process of de-commodification of food. We explore the extent to which the meaning and moral values are mutually constituted in relation to socioeconomic exchanges and environmental caring that each person experiences based on different forms of cooperation and reciprocity. Food, we suggest, is more than a commodity on the market that we may influence through our role as consumers. It is a significant focal point connecting our lives to those of others that articulates one’s relations to society in a political manner.     

Stem cell transplantation before birth – a realistic option for treatment of osteogenesis imperfecta?

Osteogenesis imperfecta (OI) is characterized by severe bone deformities, growth retardation and bones that break easily, often from little or no apparent cause. OI is a genetic disorder primarily with defective type I collagen with a wide spectrum of clinical expression. In the more severe cases, it can be diagnosed before birth. Transplantation of mesenchymal stem cells (MSC) has the potential to improve the bone structure and stability, growth and fracture healing. Prenatal and postnatal cell transplantation has been investigated in preclinical and clinical studies of OI and suggests that this procedure is safe and has positive effects. Cell transplantation resulted in improved linear growth, mobility and reduced fracture incidence. However, the effect is transient and for this reason re-transplantation may be needed. So far there is limited experience in this area, and proper studies are required to accurately determine if MSC transplantation is of clinical benefit in the treatment of OI. In this review, we summarize what is currently known in this field. © 2015 John Wiley & Sons, Ltd.