Online-Patentrecherchen — schnelle Antworten auf kritische Fragen

Online searching in publically available patent files opens up interesting possibilities to provide a rapid response to critical questions. A computerized analysis of all patents of leading German pharmaceutical companies over the last decade in important indication areas is described. Supported by subsequent manual processing of individual patents it is shown that duplicate experiments on animals practically never occur.     

Native fluorescence of unstained cryo-sections of the cervix uteri compared with histological observations

The excellent technical assistance of H. Führer and I. Leib is appreciated. Part of the work was supported by the Bundesministerium für Forschung und Technologie, the Deutsche Forschungsgemeinschaft, the Fonds der Chemischen Industrie, and from the Leitz and Hoechst companies. This paper is part of the M. D. thesis of Ch.L.     

Konzept für konzentrierte Meeresforschung an fünf Orten

Naturwissenschaften Aktuell

Konzept für konzentrierte Meeresforschung an fünf Orten     

地勘单位安全工作现状及强化安全管理对策和安全管理工作思考

本文针对目前地勘单元安全工作的现状，提出强化安全管理的对策，并结合当前国内安全生产的严峻形势，对安全管理工作进行了思考。     

Predator odour and its impact on male fertility and reproduction in Phodopus campbelli hamsters

 This study investigated the influence of cat urine odour in suppressing development and fertility in Campbell's hamster males. Exposure to this odour from postnatal day 11 until day 45 (sexual maturation) resulted in reduced sex organ weights, reduced testosterone levels and in an increase in abnormalities of the synaptonemal complex in both sex chromosomes and autosomes. Subsequent breeding experiments revealed a significant decrease in litter size. All these data indicate a severe effect of predator odour on the breeding success of potential prey species. It is assumed that these effects are caused by the sulphurous compounds in the urine; however, the underlying mechanisms are not yet known. Received: 31 January 2000 / Accepted in revised form: 6 June 2000     

A new type of infrared organ in the Australian "fire-beetle" Merimna atrata (Coleoptera: Buprestidae)

 The Australian buprestid beetle Merimna atrata (Coleoptera: Buprestidae) approaches forest fires because its larvae develop in freshly burnt wood. So far nothing is known about possible sensory systems enabling the beetles to detect fires and to cope with the thermal environment close to the flames. We found that M. atrata has two pairs of infrared (IR) organs on the ventrolateral sides of the abdomen. Each IR organ consists of a specialized IR-absorbing area which is innervated by one thermosensitive multipolar neuron. The primary dendritic branches ramify into more than 800 closely packed terminal endings which contain a large number of mitochondria. We called the special morphology of the dendritic region a terminal dendritic mass. The type of IR receptor found in M. atrata is unique in insects and can best be compared with the IR organs of boid snakes. Received: 14 August 2000 / Accepted in revised form: 18 October 2000     

Gold mining in Siberia and the Far East as a source of mercury contamination of the environment

ＩｎｔｒｏｄｕｃｔｉｏｎＳｉｂｅｒｉａａｎｄｔｈｅＦａｒＥａｓｔａｒｅｔｈｅｏｌｄｅｓｔａｎｄｔｈｅｒｉｃｈｅｓｔｇｏｌｄ ｍｉｎｉｎｇａｒｅａｓｏｆＲｕｓｓｉａ .Ｉｎｔｅｎｓｉｖｅｇｏｌｄ ｍｉｎｉｎｇｈｅｒｅｓｔａｒｔｅｄｉｎｔｈｅｂｅｇｉｎｎｉｎｇｏｆｔｈｅ 19ｔｈｃｅｎｔｕｒｙ(Ｖｙａｚｅｌｓｈｃｈｉｋｏｖ ,1963) .Ｆｏｒｔｈｅｍｏｓｔｐａｒｔｇｏｌｄ ｂｅａｒｉｎｇｏｒｅｓａｎｄｓａｎｄｓｗｅｒｅｐｒｏｃｅｓｓｅｄｗｉｔｈｔｈｅｕｓｅｏｆａｍａｌｇａｍａｔｉｏｎｍｅｔｈｏｄｆｏｒｇｏｌｄｅ…