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91.
Karen Chong Sarah Keating Stephanie Hurst Anne Summers Howard Berger Gareth Seaward Nicole Martin Tami Friedberg David Chitayat 《黑龙江环境通报》2009,29(5):489-494
Cornelia de Lange Syndrome (CdLS) is a multisystem disorder characterized by somatic defects and mental retardation. Prenatal diagnosis of this severe condition is difficult in view of the non-specific ultrasound abnormalities. We report three cases with prenatally suspected CdLS based on the ultrasound findings as well as low PAPP-A detected on first trimester screening in one case, and the results of the autopsy and the NIPBL gene mutation analysis. Copyright © 2009 John Wiley & Sons, Ltd. 相似文献
92.
Vinogradoff SI Graham MC Thornton GJ Dunn SM Bacon JR Farmer JG 《Journal of environmental monitoring : JEM》2005,7(5):431-444
As a consequence of the accumulation of anthropogenic Pb in upland catchments, there has been much recent concern about the potential mobilisation and transport of Pb from the soils to receiving waters and also the possible harmful effects that this might have on aquatic biota. This paper presents the findings of a two-year study of Pb behaviour in an organic-rich upland catchment at Glensaugh in NE Scotland. Pb inputs to the catchment were characterised by direct measurements of Pb concentration and (206)Pb/(207)Pb ratios in rain water and interception. Pb outputs from the catchment were calculated from measurements on stream water samples taken from the two main streams, the Cairn Burn and Birnie Burn. The relative contribution of Pb from groundwater and throughflow, under different flow conditions (base flow and high flow), to stream waters was investigated via analysis of springs sourced from groundwater and of waters flowing through the various soil horizons (S (surface), A, B, C, and D), respectively. The outcome of intensive sampling and analysis over the two-year time period was that, even with marked reduction in Pb inputs over the past two decades, the catchment was still acting as a net sink for the current atmospheric deposition. Although the Pb isotopic signature for stream water is very similar to that for the contemporaneous rain water ((206)Pb/(207)Pb approximately 1.15-1.16), only a small portion of the rain water is transferred directly to stream water. Instead, the Pb input is transferred to the stream waters mainly via groundwater and it was also confirmed that the latter had a similar Pb isotopic signature. From the Pb isotopic measurements on throughflow waters, however, Pb being removed via the streams contained some previously deposited Pb, i.e. mobilisation of a small portion of soil-derived anthropogenic Pb was occurring. These findings are important not only with respect to the source/sink status of the catchment but also for calculation of the extent of retention of the current atmospheric Pb inputs, which must take account of the release of previously deposited Pb from the catchment soils, a process occurring mainly under high flow conditions. 相似文献
93.
Organohalogen chemicals in human blood from the United Kingdom 总被引:1,自引:0,他引:1
Thomas GO Wilkinson M Hodson S Jones KC 《Environmental pollution (Barking, Essex : 1987)》2006,141(1):30-41
Blood serum from 154 volunteers at 13 UK locations in 2003 were analysed for a range of PCBs, organochlorine pesticides and PBDEs. HCB, p,p'-DDE and p,p'-DDT and beta-HCH were the dominant organochlorine pesticides in most samples. BDEs 47, 99, 100, 153, 154 and 183 were the most regularly detected PBDEs. This study is the first report of BDE209 in UK human blood (found in 11 samples, range < 15-240 ng/g lipid). Concentration and age correlated for the less easily metabolised PCBs, p,p'-DDT and p,p'-DDE, HCB and HCHs. With increasing age females tended to have lower concentrations of the more chlorinated PCBs than males. Similar PBDE concentrations, and distributions, to those reported in the general population in Sweden in 2002 were found, despite differences in historical PBDE production and usage. There is increasing regulation to control persistent and bioaccumulative chemicals, and establishing human exposure will help to identify substances which should be urgently phased out. 相似文献
94.
Asunción Lago-Lestón Catarina Mota Lena Kautsky Gareth A. Pearson 《Marine Biology》2010,157(3):683-688
In the Baltic Sea, the broadly distributed brown alga Fucus vesiculosus coexists in sympatry over part of its range (south west Gulf of Bothnia) with the Baltic endemic F. radicans sp. nov, while further north in colder and lower-salinity areas of the Baltic F. radicans occurs alone (north west Gulf of Bothnia). F. radicans appears to have arisen via rapid speciation from F. vesiculosus within the recent history of the Baltic (ca. 7500 BP). Possible functional divergence between the two species was investigated
by comparing stress-responsive gene expression in a common-garden experiment. The experiment used two allopatric populations
of Fucus vesiculosus from the Skagerrak (North Sea) and Central Baltic, as well as F. radicans from the same Central Baltic site. The two species in sympatry displayed divergent heat shock responses, while F. vesiculosus populations from allopatric sites did not. F. radicans was more sensitive to heat shock at 25°C, either alone or together with high irradiance and desiccation, than Baltic or Skagerrak
F. vesiculosus. The results indicate that rapid functional divergence in the inducible heat shock response has occurred between sympatric
species on a timescale of thousands of years. 相似文献
95.
The statistical treatment of data-sets from environmental pollutant studies in which different measurements are combined to produce averages or comparative factors (e.g., transfer coefficients (TCs), input-output balance values) are considered here, with particular reference to the analysis of data from input-output balance studies of pollutants such as PCBs in animals and humans. Many methods of statistical analysis ignore the fact that all measurements are subject to error, and generally assume that the normal distribution applies to all data-sets, which is commonly inappropriate for environmental (and particularly biological system) data. Considerably different estimations can be obtained by applying different, commonly used, statistical methods, as shown in a simulation study presented here and when applied to data from an input-output balance study of PCBs in humans. Alternative average and combined factor estimators for the treatment of data from these types of studies that give considerable advantages in terms of bias and the ease of assessment of accuracy are proposed. 相似文献
96.
The 2006 end-of-life vehicles (ELVs) directive target for the recycled and reused material content of an ELV has been undertaken using the current recovery infrastructure within the UK. The current expectation is that the conformance for the 2006 recycling target will be mainly achieved using existing post-fragmentation separation technologies rather than manually disassembling vehicles into their constituent materials. With the economic pressure of the current legislative targets weighing heavily on end-of-life stakeholders, and the further increase of recycling levels for 2015, it is important to understand “when” and “if” manual dismantling activities become economically viable within a dramatically changing vehicle recovery industry. This paper describes a method of costing the dismantling of specific makes and models of vehicle due for retirement in 2015, and discusses the economic implications of such practice and possible strategic directions for pre-fragmentation vehicle recovery. 相似文献
97.
Robert?K.?DixonEmail author Richard?M.?Scheer Gareth?T.?Williams 《Mitigation and Adaptation Strategies for Global Change》2011,16(1):83-102
Addressing energy, economic and environment security is a pressing challenge for nations worldwide. Global energy demand is
projected to increase by 45% during the next 20 years, with the fastest growth in developing and transition countries. Over
the past two decades, the Global Environment Facility (GEF) has invested in a portfolio of sustainable energy projects with
an emphasis on energy efficiency, renewable energy, and urban transport. These projects address many different national priorities
including infrastructure, technologies, policies, best practices, institutions, and capacity building. Since 1991, more than
US2,735 billion has been invested in energy sector projects with an additional US2,735 billion has been invested in energy sector projects with an additional US17.118 billion in co-financing from governments
and the private sector. US1,186 billion, together with US1,186 billion, together with US7,092 billion in co-finance, has been invested in energy efficiency
projects that deploy new technologies, develop institutional and human capacity, disseminate best practices, and build public
awareness and understanding. GEF renewable energy investments of US1,298 billion, with co-financing of US1,298 billion, with co-financing of US7,555 billion,
have advanced demonstration and deployment of solar thermal heating, solar thermal power, photovoltaics, wind power, geothermal
energy, small hydropower, biomass, and combined technologies and best practices across 5 continents. The GEF has invested
US251 million (with US251 million (with US2,471 billion in co-finance) in urban transport projects that address transport strategies, infrastructure,
and mobility technology solutions. These energy efficiency, renewable energy and urban transport projects contributed to the
direct reduction of about 1.7 billion tons of greenhouse gas emissions. Other tangible environmental benefits also flowed
from these GEF investments. Case studies of representative projects are presented to illustrate lessons learned from the energy
efficiency, renewable, energy, and urban transport investments. Experiences from GEF investments can inform development and
implementation of future sustainable energy investments. 相似文献
98.
Georgios Niarchos Lutz Ahrens Dan Berggren Kleja Gareth Leonard Jim Forde Jonny Bergman Erik Ribeli Matilda Schütz Fritjof Fagerlund 《补救:环境净化治理成本、技术与工艺杂志》2023,33(2):101-110
Soil and groundwater contamination by per- and polyfluoroalkyl substances (PFAS) has been a significant concern to human health and environmental quality. Remediation of contaminated sites is crucial to prevent plume expansion but can prove challenging due to the persistent nature of PFAS combined with their high aqueous mobility. In this case study, we investigated the potential of colloidal activated carbon (CAC) for soil stabilization at the pilot scale, aiming to entrap PFAS and prevent their leaching from soil into groundwater. Monitoring of the site revealed the presence of two potential sources of PFAS contamination at concentrations up to 23 μg L−1 for ∑11PFAS in groundwater. After CAC application, initial results indicated a 76% reduction of ∑11PFAS and high removal rates for long-chain PFAS, such as perfluorooctane sulfonic acid and perfluorooctanoic acid. A spike in concentrations was noticed 6 months after injection of CAC, showing a rebound of the plume and a reduction of treatment effectiveness. Based on long-term monitoring data, the treatment effectiveness for ∑11PFAS dropped to 52%. The rebound of concentrations was attributed to the plume bypass of the barrier due to the presence of high conductivity zones, which likely occurred because of seasonal changes in groundwater flow directions or the CAC application at the site. This demonstrates the need for a detailed and accurate hydrogeological understanding of contaminated sites before designing and applying stabilization techniques, especially at sites with high geologic and hydrologic complexity. The results herein can serve as a guideline for treating similar sites and help avoid potential pitfalls of remedial efforts. 相似文献