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631.
632.
We present a remarkable chain of events in which percutaneous umbilical cord sampling was performed in an attempt to clarify a situation of possible fetal sex chromosome mosaicism in an amniotic fluid culture and led to the discovery that the mother herself had a 45,X/46,XX/ 47.XXX chromosome constitution. This may have simply represented the chance concurrence of pseudo-mosaicism in the amniotic fluid culture of a woman with an abnormal sex chromosome constitution, but it is also possible that the 45,X colony was maternal in origin. Although clearly a most unusual circumstance, the possibility should be kept in mind when termination of a pregnancy is being considered because of apparent mosaicism in a prenatal diagnostic study. 相似文献
633.
Hurler's disease was excluded in a fetus at 23 weeks' gestation by demonstrating normal iduronidase activity in fetal leucocytes following failure of amniotic cell culture after amnic-centesis at 16 and 19 weeks' gestation. The diagnosis was confirmed in the neonate. 相似文献
634.
The fetal heart rate (FHR) was continuously monitored during 42 umbilical vessel punctures performed at the placental insertion of the cord in 24 diagnostic fetoscopies in which pure fetal blood was obtained. In only one patient did a deceleration first appear during puncture and aspiration of fetal blood. In two patients decelerations preceded fetoscopy and in two others they began during the fetoscopy but before puncture of an umbilical vessel. In 19 patients, the FHR did not change at all during the procedure. Fetal haemorrhage after sampling was either absent or minimal. Six pregnancies were terminated because a positive diagnosis had been made and 18 healthy babies were born. Umbilical cords were examined after 7 terminations of pregnancy and after 6 deliveries. In the former group the puncture could just be seen with the naked eye and the needle track was demonstrated histologically in 6. No traces of the puncture or other abnormalities were found in the cords after delivery. Fetal blood sampling from umbilical cord vessels, particularly at the placental insertion of the cord, is the technique of choice since pure fetal blood can be obtained without increasing the risk of fetoscopy. 相似文献
635.
True microcephaly can be diagnosed at an early stage of gestation by serial measurements of fetal head growth as demonstrated by this case report in which the diagnosis of genetic microcephaly was made but termination refused. True microcephaly was evident at birth. 相似文献
636.
637.
638.
I. Shagina H. L. Dadali V. P. Sitnikov V. V. Pugachev N. A. Malygina O. V. Evgrafov 《黑龙江环境通报》1995,15(1):27-34
Ninety-two families with spinal muscular atrophy (SMA) applied for genetic counselling and further prenatal diagnosis. To minimize expenses, only one tightly linked informative marker was determined in the course of preliminary examination, and non-radioactive allele detection was preferably used. Four prenatal diagnoses of SMA type I, four of SMA type II, and one of SMA type III were made. This trial programme shows the considerable requirements, importance, and potential effectiveness of prenatal prediction of SMA in Russia. 相似文献
639.
640.
Shamama Afreen Nitasha Sharma Rajiv K. Chaturvedi Ranjith Gopalakrishnan N. H. Ravindranath 《Mitigation and Adaptation Strategies for Global Change》2011,16(2):177-197
Due to large scale afforestation programs and forest conservation legislations, India’s total forest area seems to have stabilized
or even increased. In spite of such efforts, forest fragmentation and degradation continues, with forests being subject to
increased pressure due to anthropogenic factors. Such fragmentation and degradation is leading to the forest cover to change
from very dense to moderately dense and open forest and 253 km2 of very dense forest has been converted to moderately dense forest, open forest, scrub and non-forest (during 2005–2007).
Similarly, there has been a degradation of 4,120 km2 of moderately dense forest to open forest, scrub and non-forest resulting in a net loss of 936 km2 of moderately dense forest. Additionally, 4,335 km2 of open forest have degraded to scrub and non-forest. Coupled with pressure due to anthropogenic factors, climate change
is likely to be an added stress on forests. Forest sector programs and policies are major factors that determine the status
of forests and potentially resilience to projected impacts of climate change. An attempt is made to review the forest policies
and programs and their implications for the status of forests and for vulnerability of forests to projected climate change.
The study concludes that forest conservation and development policies and programs need to be oriented to incorporate climate
change impacts, vulnerability and adaptation. 相似文献