Microbial pollution of the blue and white Niles at Khartoum

The total coliform and fecal coliform bacterial load of the Blue and White Niles at Khartoum has been determined in the period of January–July 1984. The Blue Nile has been found to be more contaminated than the White Nile. The east bank of the White Nile was found to be more contaminated than the west bank. The microbial load of the rivers increased conspucuously as they passed through the city of Khartoum.     

Sustainable EOQ and EPQ models for a two-echelon multi-product supply chain with return policy

Environment, Development and Sustainability - In this work, a new model is developed to determine optimum sustainable economic order quantity (EOQ) and economic production quantity (EPQ) values for...     

Microwave-assisted synthesized zinc nanoparticles attenuate cisplatin-induced testicular toxicity in mice

Abstract

The purpose of this study was to investigate the protective effects of zinc nanoparticles against cisplatin-induced testicular toxicity in mice. Zinc nanoparticles were produced by microwave-assisted synthesis using Lavandula vera extract as reducing agent. Single doses of cisplatin (7?mg/kg, intraperitoneally) and ZnSO₄ (10?mg/kg, orally), and various doses of zinc nanoparticles (10???50?mg/kg, orally) and vitamin E (100?mg/kg, interaperitoneally) were administered. The protective role of zinc nanoparticles was determined biochemically and histologically. Gradual reduction in malondialdehyde levels and elevation in glutathione levels and in the activities of superoxide dismutase and catalase upon administration of zinc nanoparticles were observed. The pathology of mice treated with cisplatin/vitamin E and cisplatin/zinc nanoparticles were apparently equal, but vitamin E treatment was more effective in lowering oxidative stress markers than zinc nanoparticles. These findings suggest that co-administration of zinc nanoparticles with cisplatin could prevent adverse effects on the male reproductive system via their potential antioxidant properties.     

High-risk behaviors while driving: A population-based study from Iran

Objective: Traffic injuries are becoming one of the most important challenges of public health systems. Because these injuries are mostly preventable, the aim of this study is to evaluate the four main high-risk behaviors while driving.

Methods: This cross-sectional study was conducted on a random sample from the population of Mashhad, Iran, in 2014. A checklist and a previously validated questionnaire for the transtheoretical stages of change model (TTM) were used for data collection. Statistical analyses were performed using SPSS 11.5 software with P <.05 statistically significant.

Results: Totally 431 individuals were included with a mean age of 30 ± 11.3 years. Forty-three percent (183) were male. The TTM model revealed that participants were mostly in pre-actional phases regarding not using a cell phone while driving (80%), fastening the driver's seat belt (66%), front seat belt (68%), and rear seat belt (85%) The penalty was a protective factor only for using cellphone (odd ratio [OR] = 0.82, 95% confidence interval [CI], 0.68–0.98). Lower education (OR = 0.12, 95% CI, 0.01–0.94) and male gender (OR = 0.35, 95% CI, 0.14–0.83) were indicative of lower rates of fastening the front and rear seat belts.

Conclusion: The stages of change model among study participants is a proper reflection of the effectiveness of the current policies. More serious actions regarding these high-risk behaviors should be considered in legislation.     

A risk-based decision making approach to determine fireproofing requirements against jet fires

API Publication 2218 is one of the most referred practices for fireproofing of onshore structural supports. Despite the extensive citation, it solely considers the effects of pool fire and rarely addresses jet fire outcomes. This absence of an explicit approach is common among all the other major references. Therefore, the basic objective of this paper is to introduce a new approach for determination of the necessity for fireproofing of structural supports against jet fires. For this purpose, the flame geometry and duration of jet fires are simulated for different leak sizes in identified fire potential sources. Then, following a worst-case analysis, those structures that may be impinged by long enough flames are screened out and then characterized by maximum impingement duration for fireproofing purpose. Moreover, each structure is assigned by a failure rate to estimate the degree of vulnerability through a detailed risk assessment. In this regard a new explanatory term called Structure Failure Rate (SFR) is introduced. This approach also enables researchers to quantify the effect of other protective systems (fire and gas detection, emergency shut-down, depressurization and firewalls) on the level of required fireproofing.     

Effects of cimetidine and N-acetylcysteine on paraquat-induced acute lung injury in rats: a preliminary study

Abstract

Lung injury in rats challenged with paraquat at 20?mg kg^?1 body weight was histopathologically evident by inflammation, hemorrhage, and vascular congestion. Increased levels of reactive oxygen species and lipid peroxidation, decreased glutathione content, and lower tissue antioxidant capacity was found. The effects of N-acetylcysteine and cimetidine, a well-known potent inhibitor for organic cation transport, were examined. Lung injury was attenuated by N-acetylcysteine but not by cimetidine. The findings are consistent with the assumption that beneficial effects of N-acetylcysteine administration in paraquat-challenged animals might be linked to its ability for preserving the cellular redox environment and preventing oxidative stress, while cimetidine might even hasten paraquat-induced lung injury. On the other hand, the effects of cimetidine on paraquat-induced lung injury underline the importance of future studies on the role of transporters in this complication.