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31.
Ina Fickelscher Heike Starke Eberhard Schulze Günther Ernst Nadezda Kosyakova Hasmik Mkrtchyan Kay MacDermont Neil Sebire Thomas Liehr 《黑龙江环境通报》2007,27(8):783-785
A prenatally ascertained case with a de novo small supernumerary marker chromosome (sSMC) derived from chromosome 1 is reported. Due to a fetal heart defect the parents decided in favour of an induced abortion. Postmortem, a molecular cytogenetic study on eleven formalin fixed, paraffin-embedded tissues of the fetus was performed, to further characterize the levels of mosaicism of the sSMC(1). sSMC presence varied between 13 and 62% within different tissues of sSMC carriers. This finding is something common in sSMC carriers and could explain why up to the present no clinical correlations for sSMC mosaicism and clinical outcome in the corresponding carriers could be established. Copyright © 2007 John Wiley & Sons, Ltd. 相似文献
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33.
A. Piedra Buena F. J. González-Vila J. A. González-Pérez H. Knicker 《Chemistry and Ecology》2013,29(5):361-370
To study the characteristic N-forms of humic-type materials, samples of sapric peat from Galicia (northern Spain) were heated at 350 °C for 60, 90, 120, 150 and 180 s, and studied by Curie-point Py-GC/MS, solid-state CPMAS 13C-NMR and 15N-NMR spectroscopies. NMR analysis of the peat samples in the progressive heating stages showed the concentration of heterocyclic N-forms, the maximum structural transition amide-to-heterocyclic forms being observed in samples heated for 120 s (56% heterocyclic N and 34% aromatic C). Under more drastic conditions all N-forms were depleted. Correlation between spectroscopic and pyrolytic data betrayed specific pyrolytic markers for the different N-forms. The intensity of the 15N-NMR amide peak tended to be positively correlated to the yield of indoles, imidazoles and pyrazoles, and negatively correlated to those of benzonitriles and pyrazines. Analytical pyrolysis also showed a progressive enrichment in lipids and alkyl macromolecules with increasing heating intensity, and a decrease in lignin-derived, polysaccharide-derived and N-containing compounds. The relative abundance of non-methoxyphenolic aromatic compounds did not change. The N-compounds in peat samples unheated or heated for 60–90 s released methylpyrazole, dimethylpyrroline, methyldiphenylindole and pyrazole, whereas peat samples heated for 120 s mainly yielded methylpyrazine and methyldiphenylindole. Dimethylpyrroline and pyrazine prevailed in samples heated for 150 s, whereas samples heated for 180 s yielded mainly pyrrole. Pyrolysis data presented low possibilities for forecasting the extent of the O-alkyl domain, but reflected quantitatively the transformations in the lignin-like moiety. Both techniques coincide in pointing out the accumulation of a recalcitrant alkyl domain possibly derived from abiotic condensations or inherited lipid biomacromolecules. 相似文献
34.
Lasse Marohn Enno Prigge Karsten Zumholz Andreas Klügel Heike Anders Reinhold Hanel 《Marine Biology》2009,156(5):927-933
Otolith microchemistry is widely used as a tool to track individual migration pathways of diadromous fish under the assumption
that the elemental composition of fish otoliths is directly influenced by the physicochemical properties of the surrounding
water. Nevertheless, several endogenous factors are reported to affect element incorporation into fish otoliths and might
lead to misinterpretations of migration studies. This study experimentally examined the influence of eight different diets
on the microchemical composition of European eel (Anguilla anguilla) otoliths using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). Seven natural prey types and one
artificial diet were fed during 8 weeks in freshwater circuits. Results show for the first time that food has no significant
influence on the incorporation of Na, Sr, Ba, Mg, Mn, Cu and Y into European eel otoliths. This indicates that the incorporation
of elements usually chosen for migration studies is not affected by diet and that individual feeding behaviour of A. anguilla will not lead to any misinterpretation of migration pathways. 相似文献
35.
Organic waste and municipal solid waste usually contain considerable amounts of different nitrogen compounds, which may inhibit anaerobic degradation processes and cause problems in the downstream and peripheral devices. This refers particularly to the different process stages of anaerobic digestion, to wastewater treatment, and to exhaust air treatment. Neither the knowledge about nitrogen problems nor the technologies for elimination of nitrogen compounds from the wastewater or the exhaust air of anaerobic digestion can be regarded as state-of-the-art. Most of the technologies in question have already been applied in other areas, but are barely tested for application in anaerobic digestion plants. The few performance data and experiences at hand were mainly derived from pilot and demonstration facilities. In this paper, the problem of nitrogen will be discussed in detail according to the separate problem fields based on the authors' experience, as well as on the basis of a review of the relevant literature. Furthermore, possible solutions will be proposed and the need for further research and development will be formulated. 相似文献
36.
Heike Hildebrand Dana Kühnel Katrin Mackenzie Kristin Schirmer 《Environmental pollution (Barking, Essex : 1987)》2010,158(1):65-73
Palladium/magnetite nanoparticulate catalysts were developed for efficient elimination of halogenated organic pollutants from contaminated wastewater. Particle recovery from treated water can be ensured via magnetic separation. However, in worst-case scenarios, this catalyst removal step might fail, leading to particle release into the environment. Therefore, a toxicological study was conducted to investigate the impact of both pure magnetite and palladium/magnetite nanoparticle exposure upon human skin (HaCaT) and human colon (CaCo-2) cell lines and a cell line from rainbow trout gills (RTgill-W1). To quantify cell viability after particle exposure, three endpoints were examined for all tested cell lines. Additionally, the formation of reactive oxygen species was studied for the human cells. The results showed only minor effects of the particles on the tested cell systems and support the assumption that palladium/magnetite nano-catalysts can be implemented for a new wastewater treatment technology in which advantageous catalyst properties outweigh the risks. 相似文献
37.
Heike Schmitt Bennie Martinali Krispin Stoob Gerd Hamscher Patrick van Beelen Eric Smit Kees van Leeuwen Willem Seinen 《Environmental Sciences Europe》2006,18(2):110-118
Goal and scope
Among the human and veterinary pharmaceuticals, antibiotics form an important group. Recent research addressed the environmental ‘side effects’ of antibiotics. Evidence for environmental effects of antibiotics has for example been found for the respiratory activity of soil microorganisms. In the present contribution, results of studies on the ecotoxicology of antibiotics that are based on the utilization of carbon substrates in so-called Biolog plates are summarized.Methods, Results and Conclusions
The method of pollution-induced community tolerance (PICT) takes centre stage. PICT is based on the changes in community composition of environmental communities brought about by a toxicant, which lead to an overall increase in community tolerance to this toxicant. The suitability of such an increase in community tolerance as ecotoxicological endpoint had been the subject of several experiments. It was shown that effect testing of antibiotics requires supplementation of the communities with nutrients, and that the PICT method reveals antibiotic effects with a high specificity. In an application of PICT, effects of three classes of antibacterial compounds were investigated. Dose-response relationships were obtained for all substances, and effect concentrations were partly in the range of expected environmental concentrations. The possible risks of antibiotic use for an increase in the occurrence of antibiotic resistance genes in the environment are also touched upon, including the extent of natural resistance.Outlook
Due to its specificity, the PICT method has shown to be a suitable ecotoxicological assay. Due to possible effects of tetracyclines on the structure of the soil microbial community, it is advised to use veterinary antibiotics with caution. The risks of an increase in the occurrence of antibiotic resistance in the environment should be investigated in more detail. 相似文献38.
{en} Over the past decades, much research has focused on understanding the critical factors for marine extinctions with the aim of preventing further species losses in the oceans. Although conservation and management strategies are enabling several species and populations to recover, others remain at low abundance levels or continue to decline. To understand these discrepancies, we used a published database on abundance trends of 137 populations of marine mammals worldwide and compiled data on 28 potentially critical factors for recovery. We then applied random forests and additive mixed models to determine which intrinsic and extrinsic factors are critical for the recovery of marine mammals. A mix of life‐history characteristics, ecological traits, phylogenetic relatedness, population size, geographic range, human impacts, and management efforts explained why populations recovered or not. Consistently, species with lower age at maturity and intermediate habitat area were more likely to recover, which is consistent with life‐history and ecological theory. Body size, trophic level, social interactions, dominant habitat, ocean basin, and habitat disturbance also explained some differences in recovery patterns. Overall, a variety of intrinsic and extrinsic factors were important for species’ recovery, pointing to cumulative effects. Our results provide insight for improving conservation and management strategies to enhance recoveries in the future. 相似文献
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40.
The distribution of parasites is often characterised by substantial aggregation with a small proportion of hosts harbouring
the majority of parasites. This pattern can be generated by abiotic and biotic factors that affect hosts and determine host
exposure and susceptibility to parasites. Climate factors can change a host’s investment in life-history traits (e.g. growth,
reproduction) generating temporal patterns of parasite aggregation. Similarly, host age may affect such investment. Furthermore,
sex-biased parasitism is common among vertebrates and has been linked to sexual dimorphism in morphology, behaviour and physiology.
Studies exploring sex-biased parasitism have been almost exclusively conducted on polygynous species where dimorphic traits
are often correlated. We investigated the effects of season and life-history traits on tick loads of the monogamous eastern
rock sengi (Elephantulus myurus). We found larger tick burdens during the non-breeding season possibly as a result of energetic constraints and/or climate
effects on the tick. Reproductive investment resulted in increased larval abundance for females but not males and may be linked
to sex-specific life-history strategies. The costs of reproduction could also explain the observed age effect with yearling
individuals harbouring lower larval burdens than adults. Although adult males had the greatest larval tick loads, host sex
appears to play a minor role in generating the observed parasite heterogeneities. Our study suggests that reproductive investment
plays a major role for parasite patterns in the study species. 相似文献