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The integration of non-continuous processes such as a milk powder plant presents a challenge for existing process integration techniques. Current techniques are generally based on steady and continuous operation which for some industries is not the case. Milk production varies considerably during the year as dairy cows in New Zealand are grazed on pasture. In this paper the potential for indirect heat transfer between the several plants using a heat recovery loop and stratified tank at a typical New Zealand dairy factory is investigated. The maximum amount of heat recovery is calculated for a range of recirculation loop temperatures. The maximum amount of heat recovery can be increased considerably if the temperature of the hot fluid in the recirculation loop is varied depending on which condition the site is operating under.  相似文献   
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The American College of Obstetricians and Gynecologists currently recommends that all pregnant women be offered screening for chromosomal abnormalities, regardless of maternal age. Traditional screening tests have detection rates ranging from 85% to 90% and false-positive rates of 3% to 5%. A woman with an abnormal noninvasive test is offered a diagnostic test, but diagnostic tests are associated with a risk of pregnancy loss. Recently, analysis of cell-free fetal DNA (cffDNA) in maternal blood has been shown to have potential for the accurate detection of some of the common fetal autosomal aneuploidies. As part of a technology assessment for the California Technology Assessment Forum, we critically reviewed the evidence for the use of cffDNA as a prenatal screening test. We evaluated the evidence for its use as either a ‘primary’ or an ‘advanced’ screening test and for its use in screening for three different trisomies: 21, 18, and 13. We evaluated whether the use of cffDNA met established technology assessment criteria and established conclusions about evidence-based use of this new technology. © 2013 John Wiley & Sons, Ltd.  相似文献   
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This paper discusses the findings of a small scale research project which explored the possibility of adopting eco-design techniques. The paper focuses on identifying how eco-design techniques can be determined as being compatible with new product development processes. Via the development of a five stage ‘applicability framework’, this study demonstrates how a compatible suite of tools can be identified for application to product development processes. Testing and validation of this ‘applicability framework’, which was used to identify three key eco-design techniques; namely checklists, guidelines, and a material, energy and toxicity (MET) matrix, is shown to have taken place in relation to the development of a lightweight chemical detector product. It is established that checklists, guidelines and the MET matrix can be used both on a specific product, and also more generally in the design process. In particular, the MET matrix is shown as being used to successfully identify key environmental aspects of the product during its lifetime. The paper concludes by arguing that eco-design techniques may not have been more widely adopted by businesses because such methods are not necessarily generic and immediately applicable, but instead require some form of process-specific customisation prior to use, which can in turn act as a barrier to adoption. It is also highlighted that the shear diversity of pressures that come to bear during the product development process can also act as a barrier to adoption, and that the full integration of eco-design techniques will have to encompass approaches which overcome such pressures.  相似文献   
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The rising concentration of carbon dioxide [CO2] in the atmosphere represents an increase in a growth-limiting resource for C3 crop species. Identification of lines or characteristics of lines which have superior yield at elevated [CO2] could aid in adaptation to this global change. While intraspecific variation in responses to elevated [CO2] has been found in several species, intraspecific differences in crop yield responses to elevated [CO2] under field conditions have seldom been documented. In this 4-year study, the responses of photosynthesis, growth, pod number, seed number and size, and seed yield to the elevation of [CO2] to 180 μmol mol−1 above the current ambient concentration were examined in four varieties of Phaseolus vulgaris in the field, using open-top chambers. There was a significant variety by [CO2] interaction for seed yield, with seed yield at elevated [CO2] ranging from 0.89 to 1.39 times that at ambient [CO2] (mean 1.17×) in the different varieties, when averaged over 4 years. The highest yielding variety at elevated [CO2] was not the highest yielding variety at ambient [CO2]. The varieties with the largest and smallest yield responses both had an indeterminate growth habit. Down-regulation of photosynthesis at elevated [CO2] only occurred in the two indeterminate varieties, and there was no significant correlation between the response of single leaf photosynthetic rate and the response of seed yield to elevated [CO2] among varieties, nor between the responses of stem mass and seed yield. The change in the number of pods at elevated [CO2] was the primary determinant of the response of seed yield. These results indicate that significant variation in the response of seed yield to elevated [CO2] under field conditions does exist among varieties of P. vulgaris, and that variation in the response of pod and seed number may be more important than variation in photosynthetic response.  相似文献   
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Riparian seeps have been recognized for their contributions to stream flow in headwater catchments, but there is limited data on how seeps affect stream water quality. The objective of this study was to examine the effect of seeps on the variability of stream NO3‐N concentrations in FD36 and RS, two agricultural catchments in Pennsylvania. Stream samples were collected at 10‐m intervals over reaches of 550 (FD36) and 490 m (RS) on 21 occasions between April 2009 and January 2012. Semi‐variogram analysis was used to quantify longitudinal patterns in stream NO3‐N concentration. Seep water was collected at 14 sites in FD36 and 7 in RS, but the number of flowing seeps depended on antecedent conditions. Seep NO3‐N concentrations were variable (0.1‐29.5 mg/l) and were often greater downslope of cropped fields compared to other land uses. During base flow, longitudinal variability in stream NO3‐N concentrations increased as the number of flowing seeps increased. The influence of seeps on the variability of stream NO3‐N concentrations was less during storm flow compared to the variability of base flow NO3‐N concentrations. However, 24 h after a storm in FD36, an increase in the number of flowing seeps and decreasing streamflow resulted in the greatest longitudinal variability in stream NO3‐N concentrations recorded. Results indicate seeps are important areas of NO3‐N delivery to streams where targeted adoption of mitigation measures may substantially improve stream water quality.  相似文献   
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Surface water methane (CH4) and nitrous oxide (N2O) concentrations and fluxes were investigated in two subtropical coastal embayments (Bramble Bay and Deception Bay, which are part of the greater Moreton Bay, Australia). Measurements were done at 23 stations in seven campaigns covering different seasons during 2010-2012. Water-air fluxes were estimated using the Thin Boundary Layer approach with a combination of wind and currents-based models for the estimation of the gas transfer velocities. The two bays were strong sources of both CH4 and N2O with no significant differences in the degree of saturation of both gases between them during all measurement campaigns. Both CH4 and N2O concentrations had strong temporal but minimal spatial variability in both bays. During the seven seasons, CH4 varied between 500% and 4000% saturation while N2O varied between 128 and 255% in the two bays. Average seasonal CH4 fluxes for the two bays varied between 0.5 ± 0.2 and 6.0 ± 1.5 mg CH4/(m2·day) while N2O varied between 0.4 ± 0.1 and 1.6 ± 0.6 mg N2O/(m2·day). Weighted emissions (t CO2-e) were 63%-90% N2O dominated implying that a reduction in N2O inputs and/or nitrogen availability in the bays may significantly reduce the bays' greenhouse gas (GHG) budget. Emissions data for tropical and subtropical systems is still scarce. This work found subtropical bays to be significant aquatic sources of both CH4 and N2O and puts the estimated fluxes into the global context with measurements done from other climatic regions.  相似文献   
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