The in utero diagnosis and management of alloimmune thrombocytopenia

A case is presented in which percutaneous umbilical sampling (PUBS) was utilized in the second and third trimesters for the diagnosis and management of a pregnancy at risk for neonatal alloimmune thrombocytopenia (NAIT).     

Hopanoid Biosynthesis and Function in Bacteria

   Hopanoids are pentacyclic triterpenoid lipids occurring in bacteria. They are synthesized from isopentenyl units which are formed in a new biosynthetic route leading to isopentenyl diphosphate. Six C₅ units are joined to form squalene, the immediate precursor in hopanoid synthesis. In a highly complex cyclization reaction that shares considerable similarities with that of oxidosqualene to sterols, the hopane skeleton is formed from squalene by the squalene-hopene cyclase. Recent elucidation of the X-ray structure of this membrane-bound cyclase has shed some light on the properties of this unusual enzyme. The active site is located in a cavity within the enzyme. The squalene substrate diffuses through a channel structure from the membrane into this cavity and is there transformed into hopene. Polar side chains are attached to hopene resulting in the amphiphilic molecular structure of many hopanoids. These hopanoids are membrane components involved in regulating membrane fluidity and stability. However, the many structural variants of hopanoids indicate that they may have other interesting but as yet unknown functions.     

微机上冲裁CAD系统的开发

此文介绍了一套在微机上开发的冲裁CAD系统。它以Foxbase作为数据库管理系统,Trubo C为编程语言,能进行冲裁件图形输入与显示、工艺性分析、优化单排排样和选择板材规格、冲裁件尺寸识别和模具刃口尺寸计算、冲裁力和压力中心计算、以及凹模周界尺寸计算等。本系统主界面为下拉式菜单界面,全中文提示,人机界面友好,具有较好的可扩充性和容错性。     

Seven suggestive quantitative trait loci influence hygienic behavior of honey bees

In 1964, Walter Rothenbuhler proposed a two-gene model to explain phenotypic variance in the remarkable behavior in which honey bee workers remove dead brood from their colonies. Rothenbuhler's model proposed that one locus controls the uncapping of brood cells containing dead pupae, while a second controls the removal of the cell contents. We show here, through molecular techniques and quantitative trait loci (QTL) linkage mapping, that the genetic basis of hygienic behavior is more complex, and that many genes are likely to contribute to the behavior. In our cross, we detected seven suggestive QTLs associated with hygienic behavior. Each detected QTL controlled only 9-15% of the observed phenotypic variance in the character.     

浅谈原子吸收分光光度计在环境监测中的应用

本文介绍了原子吸收分光光度计在环境监测中的应用情况和重要性。分析了原子吸收光度法（包括石墨炉法）与ICP-AES（电感偶合等离子体发射光谱法），原子荧光法，极谱法在分析元素时各自的优缺点，又从目前环境监测的角度阐述了应用原子吸收分光度计的重要性与现实性。分析了原子吸收分光广度计在使用中的常见问题及原子吸收分光广度法分析中常出现的问题（从仪器、方法角度分别讲述）。并提出了原子吸收分光度计要进一步应适应环境监测的需求。