石墨烯类纳米材料作为药物载体的研究进展及其潜在风险

石墨烯作为一种新兴的二维碳纳米材料,近年来受到了医学领域科学家的高度关注。由于石墨烯类纳米材料具有较大的比表面积,易于表面修饰等优点,目前在药物载体方面的研究发展迅速。随着纳米技术的发展,除了氧化石墨烯外,进一步将还原氧化石墨烯、石墨烯量子点、石墨烯纳米带等石墨烯类纳米材料作为药物载体应用到医学领域。本文综述了石墨烯类纳米材料作为药物载体在医学领域的研究进展,并从石墨烯类纳米材料的相关毒性研究角度,提醒了人们负载药物前后石墨烯类纳米材料的迁移规律对其潜在风险研究的重要性。     

Improving land use inference by factorizing mobile phone call activity matrix

Land use is shaped by human activities. Traditional methods of measuring land uses (e.g. surveys and remote sensing techniques) often have difficulties in capturing human activities. The near-ubiquitous coverage of mobile phones opens up a new way to investigate land use through human activities. We propose to analyze land use by characterizing human activity patterns based on the aggregated call volume, and apply non-negative matrix factorization to identify fundamental behavioral classes. Using tower-based call data from Dakar, Senegal, we discover two fundamental land use patterns: commercial/business/industrial (C/B/I) and residential. Then, the land use of the reception area of each cell tower can be inferred based on the weights obtained for each basis vector. To evaluate the proposed approach, the results are compared with two points-of-interest (POI) data sets obtained from OpenStreetMap and Facebook’s Graph API. We have found that a majority of POIs like embassies, offices, and hotels are located in the predicted C/B/I areas; specifically, there is a strong positive correlation between estimated land use weights and the number of related POIs. Furthermore, we have shown analyzing 24-h call pattern matrix can track daily land use changes.     

用陶土吸附处理含镍废水的研究

进行了用陶土吸附处理模拟含Ｎｉ＾２＋废水的研究,探讨了陶土用量,吸附时间、废水酸度,废水中Ｎｉ＾２＋的初始浓度及吸附温度对镍去除率的影响,并用实际含镍废水进行了验证。     

基于“互联网＋”的海外员工健康管理 平台设计及应用

针对目前国内健康管理存在健康信息采集来源狭窄、健康指标数据利用效率低、信息化水平和功能与用户及社会发展不匹配等问题,设计开发了基于"互联网+"的海外油田员工健康管理信息化平台。通过运用互联网技术,使健康管理更加快捷化、流程化和规范化,实现了员工出国前健康体检、出国前健康评估和出国后健康监测的全业务流程在线管控,同时系统自动采集体检报告,形成完整的员工健康档案,提升了员工健康管理水平,为海外油田员工体检套餐优化、重点疾病防控和出国健康评估等提供了全面的数据决策依据。     

铁路隧道地下水环境动态监测体系的探讨与实践

铁路隧道排放地下水对隧道区域生态环境和人居环境的影响日益受到重视。在阐述监测等级、监测范围、监测对象和方法等的基础上,探讨了铁路隧道地下水环境动态监测体系,并在国内某货运铁路进行了系统实践。通过对48座隧道143处监控点位近3个水文年的系统监测,发现了34处隧道施工造成的失水水源点位;以典型隧道为例,总结说明黄土丘陵地区、基岩山区和岩溶地区监测结果,并讨论监测体系应用效果。     

Mechanisms of photosynthetic inactivation on growth suppression of Microcystis aeruginosa under UV-C stress

This study aims to investigate the effects of UV-C irradiation on photosynthetic processes of Microcystis aeruginosa to unravel the mechanism(s) involved in how and in what ways UV-C mediates growth suppression and cellular recovery. Changes in the concentration of photosynthetic pigments, photochemical efficiency, PS II core protein (D1) content, and the coding genes expressions were measured. The results indicate that UV-C doses at 20–200 mJ cm⁻² lead to rapid reduction in gene expression of both psbA (for D1) and cpc (for phycocyanin), but the suppression was short term and recoverable within 3 d of post-UV incubation. Conversely, UV-C doses at ?50 mJ cm⁻² could induce marked decline in photochemical efficiency (represented by the optimal PS II quantum yield, F_V/F_M, and the effective PS II quantum yield, Y) as well as decreases in D1 content and water soluble pigments (phycoerythrins, phycocyanins, allophycocyanins) in M. aeruginosa during the post UV-C incubation period. The results suggest that interruption of both the light energy harvesting apparatus (especially the water soluble pigments) and the photochemical process mainly accounted for the growth suppression effect in UV-C irradiated M. aeruginosa.     

Performance evaluation and application of surface-molecular-imprinted polymer-modified TiO2 nanotubes for the removal of estrogenic chemicals from secondary effluents

The removal of estrogenic chemicals during wastewater reclamation has been a great concern. Current advanced treatment processes are inefficient for the removal of estrogenic chemicals from secondary effluents of municipal wastewater treatment plants (WWTPs) due to the coexistence of other pollutants with less environmental significance which are also removed simultaneously. The search for highly selective and low-cost removal methods is warranted. Therefore, surface-molecular-imprinted polymer-modified TiO₂ nanotube (S-MIP-TiO₂ NT) photocatalysts were fabricated, characterized, and tested for the removal of estrogenic pollutants from wastewater in this study for the first time. Scanning electron microscopy and Fourier-transform infrared spectroscopy studies showed that the TiO₂ NTs (with an average diameter of 60 nm) were successfully imprinted with functional groups (i.e., carboxyl). The adsorption selectivity and photocatalytic activity of the S-MIP-TiO₂ NTs towards template compound (17β-estradiol, E2) were improved, compared with neat TiO₂ NTs. Interestingly, S-MIP-TiO₂ NTs exhibited higher adsorption intensity and photocatalytic selectivity at low concentrations (from 10 ng/L to 100 μg/L, as normal estrogenic chemical concentrations in secondary effluents) of E2 than that at high concentrations (from 10 to 1,000 mg/L). It was also found that some representative estrogenic chemicals and estrogenic activity could be selectively and rapidly removed from secondary effluents of municipal wastewater treatment plants using S-MIP-TiO₂ NTs as photocatalysts. In addition, S-MIP-TiO₂ NT photocatalysts exhibited excellent regeneration characteristics. Photocatalytic treatment using S-MIP-TiO₂ NTs could be a promising approach for the effective removal of estrogenic chemicals from secondary effluents of municipal WWTPs.     

基于模糊综合评判的汶川8.0级地震重灾区滑坡泥石流气候风险评估

用1971-2000年的30年逐日降水量资料,按旬统计汶川地震重灾县5-12月各旬的雨日、中雨日、大雨日、暴雨日的平均日数和气候概率,根据地震重灾区实际地质环境条件,降低强降雨强度条件,基于模糊综合评判法,按照最大隶属度原则对汶川特大地震重灾区的39个县进行地质灾害时空气候风险评估。结果表明:重灾区的地质灾害气候风险指数值存在两个高值期间,一个是5月中旬至7月上旬,另一个是8月下旬至9月下旬。而10月下旬至次年4月,重灾区降雨明显减少,绝大部分地区没有地质灾害气候风险;从地域分布来看,高风险区域主要集中在重灾区的西部和中部,风险等级为3～4级(风险较大或很大),东部地区风险等级为1～2级(中等风险或风险较小),但7月下旬高等级风险区位置集中在重灾区的南部和东部。