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排序方式: 共有250条查询结果,搜索用时 15 毫秒
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Michael Beck MD Susanne Braun Wiltrud Coerdt Eberhard Merz Elisabeth Young Adrian C. Sewell 《黑龙江环境通报》1992,12(12):1019-1029
A fetus with mucopolysaccharidosis type IV A (Morquio type A) is described. The family had one affected child exhibiting symptoms of classical Morquio A disease, and late in the subsequent pregnancy prenatal diagnosis was requested. At 23 weeks' gestation, moderate ascites was detected by detailed ultrasound scan and keratan sulphate was found in the amniotic fluid. The pregnancy was terminated by prostaglandin induction and the diagnosis of mucopolysaccharidosis type IV A was confirmed by demonstration of a deficiency of N-acetylgalactosamine-6-sulphate (GalNac-6-S) sulphatase in cultured amniotic cells and in post-mortem fibroblast cultures. The activities of β-galactosidase and arylsulphatase A were normal, ruling out Morquio disease type B and multiple sulphatase deficiency. These results indicate that mucopolysaccharidosis IV A (a disease that predominantly affects the skeletal system) may produce ascites in the fetus to such an extent that it can be detected by ultrasound. 相似文献
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206.
Hofstee C Gutiérrez Ziegler C Trötschler O Braun J 《Journal of contaminant hydrology》2003,67(1-4):61-78
A common aspect of innovative remediation techniques is that they tend to reduce the interfacial tension between the aqueous and non-aqueous phase liquids, resulting in mobilization of the organic contaminant. This complicates the remediation of aquifers, contaminated with Dense Non-Aqueous Phase Liquids (DNAPLs), as they are likely to migrate downwards, deeper into the aquifer and into finer layers. A possible solution is the use of swelling alcohols, which tend to reduce the density difference between the aqueous phase and the DNAPL. To avoid premature mobilization upon the initial contact between the DNAPL and the alcohol, several researchers have proposed the use of vertical upward flow of the alcohol. In this paper, we present an equation, which describes the upward mobilization of both continuous and discontinuous DNAPLs and so the important parameters governing the upward controlled mobilization of the DNAPL. The need and required magnitude of this specific discharge was investigated by conducting four column experiments in which the initial density of the DNAPL and the permeability was varied. It was shown that the required flow velocities increase with the permeability of the porous medium and the initial density difference between the aqueous phase and the DNAPL. Whenever the specific discharge falls below the critical value, the DNAPL moves downward. A second set of column experiments looked at the impact of permeability of porous medium on the solubilization and mobilization of DNAPL during alcohol flooding. Columns, packed with coarse or fine sand, containing a residual trichloroethylene (TCE) or perchloroethylene (PCE) saturation were flushed with the alcohol mixture at a fixed specific discharge rate. The induced pressure gradients in the aqueous phase, which were higher in the fine sand, resulted for this porous medium in extensive mobilization of the DNAPL against the direction of the buoyancy force. The density of the first NAPL coming out of the top of the fine sand was close to that of the pure DNAPL. In the coarser sand, the pressure gradients were sufficient to prevent downward migration of the DNAPL, but upward mobilization was minimal. The predominant removal mechanism in this case was the much slower solubilization. 相似文献
207.
Abundance and sources of ambient dioxins in Hong Kong: a review of dioxin measurements from 1997 to 2001 总被引:1,自引:0,他引:1
Ambient measurements of seventeen 2,3,7,8-polychlorinated dibenzo-p-dioxin/dibenzofuran congeners (2,3,7,8-PCDD/Fs) have been taken in a number of monitoring programs or ad-hoc studies in Hong Kong. The longest monitoring program started at two locations in the territory in July 1997. The other monitoring efforts are ad-hoc studies, varying from a few coordinated sampling events at multiple sites to a year-long monitoring project that targeted suspected local dioxin sources. In this paper, we examined these measurements to understand the ambient levels, temporal and spatial variation, and possible sources of the 2,3,7,8-PCDD/Fs in Hong Kong. The territory-wide annual average concentration of the dioxins was 0.052 pg I-TEQ/m3 measured at the regular monitoring stations in the most recent annual cycle of 2000/2001. This level fell at the lower end of the range of dioxin concentrations measured at other urban locations around the world. The dioxin levels showed a clear seasonality in that elevated concentrations were observed in the winter and lower concentrations in the summer at all monitoring sites with one year or more regular measurements. The measurements indicated that the few known local dioxin sources, including a major chemical waste incinerator facility, landfill sites, and vehicular traffic, are not important contributors to ambient dioxins in Hong Kong. On days of high dioxin concentrations, the 2,3,7,8-PCDD/F congeners were observed to have almost identical compositions with a north-northwest to south-southeast spatial gradient in concentrations at different sampling locations in Hong Kong. This observation, along with other collaborative evidence, established a strong link between high dioxin concentration days in Hong Kong and regional transport of the polluted air masses from the north. 相似文献
208.
Five regression models (Poisson, negative binomial, quasi-Poisson, the hurdle model and the zero-inflated Poisson) were used to assess the relationship between the abundance of a vulnerable plant species, Leionema ralstonii, and the environment. The methods differed in their capacity to deal with common properties of ecological data. They were assessed theoretically, and their predictive performance was evaluated with correlation, calibration and error statistics calculated within a bootstrap evaluation procedure that simulated performance for independent data. 相似文献
209.
To assess the fitness consequences of foraging on patchy resources, consumption rates, growth rates and survivorship of Armadillidium vulgare were monitored while feeding in arenas in which the spatial distribution of patches of high quality food (powdered dicotyledonous leaf litter) was varied within a matrix of low quality food (powdered grass leaf litter). Predictions from behavioural experiments that these fitness correlates would be lower when high quality food is more heterogeneously distributed in space were tested but not supported either by laboratory or field experiments. To investigate whether A. vulgare can develop the ability to relocate high quality food patches, changes in foraging behaviour, over a comparable time period to that used in the fitness experiments, were monitored in arenas in which there was a high quality food patch in a low quality matrix. A. vulgare increased its ability to relocate the position of high quality food over time. It reduced time spent in low quality food matrices and increased time spent in high quality food patches with time after the start of the experiment. When the position of a high quality food patch was moved, the time spent in the low quality food matrix increased and less time was spent in high quality food patches, compared to arenas in which the food was not moved. The fitness benefits for saprophages of developing the ability to relocate high quality patches while foraging in spatially heterogeneous environments are discussed. 相似文献
210.
Summary. Domestic apple (Malus pumila)- and hawthorn (Crataegus sp.)-infesting races of Rhagoletis pomonella, Walsh (Diptera: Tephritidae) provide an excellent model to examine the role that host plant specificity plays during sympatric
speciation (i.e., divergence in the absence of geographic isolation). Previous work has shown that these races differ in their propensities
to accept apple and hawthorn fruits in behavioral choice assays, and that this discrimination translates into "host fidelity"
in the field (i.e., apple flies tend to mate on and oviposit into apples and hawthorn flies on hawthorns). ?We present the results of a study
examining possible physiological factors contributing to host choice differences in R. pomonella. We tested whether apple and hawthorn flies differ in their electroantennogram (EAG) responses to biologically relevant volatile
compounds emitted from apples and hawthorns. Significant differences were found in the relative EAG responses of apple and
hawthorn flies to host fruit compounds at five of six paired study sites across the eastern United States. The geographic
pattern of EAG variation was complex, however, with local populations of apple and hawthorn flies tending to be more similar
to one another than to flies of the same race at distant sites. This pattern was largely due to EAG responses for several
compounds showing longitudinal or latitudinal clines, the latitudinal clines being similar to those observed for allozyme
loci in the host races. We also found evidence for sex-related differences, as males tended to have higher mean EAG responses
to compounds than females. Host-associated differences were therefore nested within geographic and sex-related differentiation
in R. pomonella.?Further behavioral studies are needed to distinguish whether the EAG differences are responsible for, as opposed to being
a consequence of, host-plant fidelity and adaptation. Crosses are also required to establish a genetic basis for the EAG responses,
although we did find significant correlations between EAG scores for several compounds and the allozymes NADH-Diaphorase-2
and Hydroxyacid dehydrogenase at one of the study sites. Questions therefore remain concerning the evolutionary significance
of the EAG response differences between apple and hawthorn fly races. Nevertheless, these differences raise the possibility
that antennal responses to fruit-related volatile compounds contribute to host plant discrimination in R. pomonella. Regardless, the EAG responses represent another set of traits, in addition to diapause/eclosion time phenotypes and allozyme
frequencies, differing between apple and hawthorn host races of R. pomonella.
Received 17 March 1998; accepted 21 September 1989. 相似文献