Circulating ‘trophoblast’ cells in pregnancy have maternal genetic markers

A syncytiotrophoblast-associated antigen identified by the monoclonal antibody (McAb) H315 is detectable on the surface of a low proportion of peripheral blood cells in pregnant women, raising the possibility of a new approach to prenatal diagnosis of genetic disorders. We aimed at verifying the trophoblastic origin of H315⁺ cells and their use for prenatal diagnosis of β-thalassaemia. H315 ⁺ cells were separated from the peripheral blood of pregnant women: the DNA obtained from these cells in two selected cases was shown to have genetic markers indistinguishable from those of the mother and definitely different from the fetus. Our results suggest that H315 antigen is expressed by maternal cells and that prenatal diagnosis on peripheral blood of the mother using H315 McAb is not feasible.     

用多硫化物同时去除高浓度含氰电镀废水中氰和重金属的研究

研究表明,用多硫化物处理高浓度含氰电镀废水的同时,亦可有效地去除废水中的重金属,其方法操作简便。本文对实际应用中所需的工艺条件、反应产物硫氰化物的去向、残余多硫化物的处理、多硫化物的合成、反应热效应等进行了研究,取得了满意的结果。