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Ahmad N. Abou Tayoun Nancy B. Spinner Heidi L. Rehm Robert C. Green Diana W. Bianchi 《黑龙江环境通报》2018,38(1):26-32
Clinical diagnostic laboratories are producing next-generation sequencing-based test results that are becoming increasingly incorporated into patient care. Whole genome and exome sequencing on fetal material derived from amniocytes, chorionic villi, or products of conception is starting to be offered clinically in specialized centers, but it has not yet become routine practice. The technical, interpretation, and ethical challenges are greatest in the area of prenatal medicine because the fetus has a limited health history, and the physical examination is only indirectly available via prenatal sonography. Here, we provide an overview of these challenges and highlight the clinical utility, reporting, and counseling issues associated with prenatal DNA sequencing. Future considerations are also discussed. © 2017 John Wiley & Sons, Ltd. 相似文献
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Joke Muys Yves Jacquemyn Bettina Blaumeiser Laura Bourlard Nathalie Brison Saskia Bulk Patrizia Chiarappa Anne De Leener Marjan De Rademaeker Julie Désir Anne Destrée Koenraad Devriendt Annelies Dheedene Armelle Duquenne Annelies Fieuw Erik Fransen Jean-Stéphane Gatot Mauricette Jamar Sandra Janssens Jorien Kerstjens Kathelijn Keymolen Damien Lederer Björn Menten Bruno Pichon Sonia Rombout Yves Sznajer Ann Van Den Bogaert Kris Van Den Bogaert Joris Vermeesch Katrien Janssens 《黑龙江环境通报》2020,40(10):1272-1283
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Increasingly, a key component in the financial success of developing and operating domestic and international energy projects is the management of environmental issues. This article outlines an environmental management system for developing and acquiring power projects. The specific issues addressed include the development and communication of an environmental policy and the development and use of environmental expectations. These expectations are designed to manage the environmental components of the dynamic development process and provide a framework for enhancing team effectiveness in addressing environmental issues. Examples of expectations for each development phase are provided. © 1998 John Wiley & Sons, Inc. 相似文献
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Laura E Ellison Thomas J O'Shea Daniel J Neubaum Richard A Bowen 《Ecological applications》2007,17(2):620-627
We investigated movements of female big brown bats (Eptesicus fuscus) roosting in maternity colonies in buildings in Fort Collins, Colorado (USA), during the summers of 2002, 2003, and 2005. This behavior can be of public health concern where bats that may carry diseases (e.g., rabies) move among buildings occupied by people. We used passive integrated transponders (PIT tags) to mark individual bats and hoop PIT readers at emergence points to passively monitor the use of building roosts by marked adult females on a daily basis during the lactation phase of reproduction. Multi-strata models were used to examine movements among roosts in relation to ambient temperatures and ectoparasite loads. Our results suggest that high ambient temperatures influence movements. Numbers of mites (Steatonyssus occidentalis) did not appear to influence movements of female bats among building roosts. In an urban landscape, periods with unusually hot conditions are accompanied by shifting of bats to different buildings or segments of buildings, and this behavior may increase the potential for contact with people in settings where, in comparison to their more regularly used buildings, the bats may be more likely to be of public concern as nuisances or health risks. 相似文献
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The catalytic effects of copper and iron compounds were examined for their behavior in promoting formation of chlorine (Cl2), the major chlorinating agent of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs), in an environment simulating that of municipal waste fly ash. Formation of Cl2 occurred as a result of a metal-catalyzed reaction of HCl with O2. Catalytic activity was greatest at a temperature of approximately 400 °C, supporting a theory of de novo synthesis of PCDDs and PCDFs on fly ash particles downstream of waste combustion. 相似文献