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371.
Objectives. The economic burden of work-related musculoskeletal disorders (WMSDs) is industry specific. The objective was to analyse compensation claims for WMSDs among restaurant workers in France taking into account the type of restaurant. Methods. Data for 2014 were obtained from the French National Health Insurance Fund for Salaried Workers. A chi-square test was used to compare claims, incapacity and lost work day rates in different types of restaurant. Results. Prevalence for WMSDs differed significantly by the type of kitchen: collective restaurant (7.2/1000 workers), traditional restaurant (1.7/1000), and fast food restaurant (1.0/1000). There were more male claimants in traditional restaurant workers (51.0%) than in collective restaurant workers (40.1%) but more female claimants in collective restaurant workers (50.1%) than in traditional restaurant workers (39.4%). Permanent incapacity was significantly more prevalent in collective restaurant workers (49.6%), than in traditional (41.9%) and fast food (8.5%) restaurant workers. In collective restaurant workers, as a percentage, claims, permanent incapacity and lost work days increased with age range or work experience. Conclusions. Prevalence for WMSDs and therefore incapacity and lost work days are different according to the type of restaurant. Preventive strategies should take these differences into consideration.  相似文献   
372.
Contaminants including flame retardants, antimicrobial agents and phthalates, occurring as residues in human tissues were associated with altered endocrine function. In our study we analysed the flame retardants tetrabromobisphenol A (TBBPA), hexabromocyclodecane (HBCD), penta-bromodiphenylether (BDE-100) and hexa-BDE (BDE-155), the antimicrobial compounds triclosan (TCS) and triclocarban (TCC) and eight phthalates for their androgenic and antiandrogenic activity in vitro in the MDA-kb2 cell line. No or only weak androgenic activity was observed for all the tested compounds. TBBPA showed weak antiandrogenic activity, which was demonstrated for the first time. The flame retardants HBCD, BDE-100 and BDE-155 enhanced the dihydrotestosterone-dependent activation of androgen receptor-responsive gene expression but exhibited little or no agonistic activity. The enhancement reached 150%, which was similar to the antimicrobials (TCS up to 180%, and TCC up to 130%). This enhancement of androgenic activity represents a novel mode of action of the endocrine activity of flame retardants. In contrast, most phthalates showed antiandrogenic activity. Butylbenzyl phthalate (BBP), dibutyl phthalate (DBP) and diethyl phthalate (DEP) showed strong antiandrogenicity, whereas the action of diethylhexyl phthalate (DEHP), dipentyl phthalate (DPP), dimethyl phthalate (DMP), and the DEHP metabolite monoethylhexyl phthalate (MEHP) was lower. Our in vitro study demonstrates for the first time a weak antiandrogenic activity of TBBPA, and a significant enhancement of the androgenic activity of HBCD, BDE-100 and BDE-155, which represents a novel mechanism of hormonal activity of flame retardants.  相似文献   
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Environmental Modeling & Assessment - Poverty is a major determinant for pollution exposure, according to the US location choice literature. In this paper, we assess the impact of...  相似文献   
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Second-generation anticoagulant rodenticides are widely reported to contaminate and poison nontarget wildlife, primarily predatory birds and mammals. Exposure pathways, however, have not been well defined. Here, we examined potential movement of rodenticides from deployment of bait to exposure of small mammals and other biota. At two adjacent working farms, we placed baits containing either brodifacoum or bromadiolone. We monitored movement of those compounds to the surrounding environment by collecting small mammals, birds, and invertebrates. Similar collections were made at a third agricultural setting without active bait deployment, but located among intensive livestock production and regular rodenticide use by farmers. Livers and whole invertebrate samples were analyzed for rodenticides using a sensitive LC-MSMS method. Norway rats (Rattus norvegicus) from both baited and non-baited farms had residues of brodifacoum or bromadiolone, implicating rats as an important exposure pathway to wildlife. Among 35 analyzed nontarget small mammals, a single vole had high hepatic residues (18.6 μ/g), providing some indication of a small mammal pathway. One song sparrow (Melospiza melodia) sample from a baited farm contained 0.073 μg/g of brodifacoum in liver, while 0.39 μg/g of diphacinone was measured in a pool of carrion beetles (Dermestes spp.) from the non-baited farm area, implicating avian and invertebrate components in exposure pathways. Regurgitated pellets of barn owl (Tyto alba) selected randomly from baited farms contained no detectable rodenticide residues, while 90 % of owl pellets collected from a variety of farms, and selected for the presence of rat fur, contained detectable anticoagulant residues. We recorded behavior of a captive sample of a representative songbird, the house sparrow (Passer domesticus); they readily entered bait stations and fed on (unloaded) bait.  相似文献   
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International institutions, understood as sets of rules contained in international agreements, are aimed at orienting national governments towards specific policy options. Nevertheless, they can determine a change in national policies and practices only if states are willing and capable of incorporating international obligations into their national legislations and ensuring their application and enforcement in areas that follow completely under national jurisdiction. The establishment of marine protected areas promoted by international agreements as a tool for the protection of marine resources represents an interesting case for revealing the complex interactions between international institutions and national actors. Particularly, the establishment of these areas in Senegal shows the salience of domestic constellations of actors who may support or undercut national commitments to international regimes: political elites, bureaucracies, the general public and target groups. By anchoring the empirical analysis to an actor-centred institutionalist perspective, the article explains how dynamic constellations of actors can distort the penetration of international objectives in the national policy framework. Different constellations of national actors can indeed bend international institutions at different moments: during the formulation of a new law in line with international obligations; in the definition of its implementation framework; and in the enforcement of national policies.  相似文献   
379.
The number of MPAs has increased sharply, from just 118 in 1970 to well over 6,300 today. This growth in numbers has also been accompanied by a voluminous growth in the academic literature on the theme, with writers employing ecologic, economic and governance lenses (or a combination thereof) to both support the case for MPA creation, and to evaluate just how successfully (or not) existing MPAs match up to their promises. Research suggests effective management of such protected areas is vital if desired outcomes are to be achieved within the allotted time period. This Special Feature on MPAs therefore seeks to address two key questions derived from the management effectiveness framework of Hockings and others (2000), namely: ‘How appropriate are the management systems and processes in place?’ and ‘Were the desired Objectives achieved—and if so, why?’ Fourteen articles, drawing on different disciplinary perspectives relating to MPA experiences from across the globe, offers insights into these questions by considering, inter alia, how: are MPA sites selected?; is ‘buy-in’ to the process from the various stakeholders achieved?; are these stakeholder’s views reflected in the management systems that evolve?, and what monitoring and evaluation mechanisms are in place? Bringing these perspectives and approaches together through the medium of this Special Feature is thus intended to further our understanding of the different issues that may confront both planners and managers of Marine Protected Areas.  相似文献   
380.
The Nile Deep-Sea Fan (NDSF) is located on the passive continental margin off Egypt and is characterized by the occurrence of active fluid seepage such as brine lakes, pockmarks and mud volcanoes. This study characterizes the structure of faunal assemblages of such active seepage systems of the NDSF. Benthic communities associated with reduced, sulphidic microhabitats such as sediments and carbonate crusts were sampled by remotely operated vehicles during two cruises in 2006 (BIONIL) and 2007 (MEDECO). Environmental conditions and biological factors including family-level faunal composition, density and diversity were measured at local and regional scales. Significant differences were detected at different spatial scales: (1) the fauna of reduced habitats differed substantially in activity, diversity and biomass from the non-seep environment at similar water depth, (2) cold seep microhabitats showed differences in community structure and composition related to substratum type as well as to the intensity and location of fluid emissions.  相似文献   
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