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251.
Sandra Vranic Ignacio Garcia-Verdugo Cécile Darnis Jean-Michel Sallenave Nicole Boggetto Francelyne Marano Sonja Boland Armelle Baeza-Squiban 《Environmental science and pollution research international》2013,20(5):2761-2770
Because of an increasing exposure to environmental and occupational nanoparticles (NPs), the potential risk of these materials for human health should be better assessed. Since one of the main routes of entry of NPs is via the lungs, it is of paramount importance to further characterize their impact on the respiratory system. Here, we have studied the uptake of fluorescently labeled SiO2 NPs (50 and 100 nm) by epithelial cells (NCI-H292) and alveolar macrophages (MHS) in the presence or absence of pulmonary surfactant. The quantification of NP uptake was performed by measuring cell-associated fluorescence using flow cytometry and spectrometric techniques in order to identify the most suitable methodology. Internalization was shown to be time and dose dependent, and differences in terms of uptake were noted between epithelial cells and macrophages. In the light of our observations, we conclude that flow cytometry is a more reliable technique for the study of NP internalization, and importantly, that the hydrophobic fraction of lung surfactant is critical for downregulating NP uptake in both cell types. 相似文献
252.
David P. Chock Sandra L. Winkler Colin Chen 《Journal of the Air & Waste Management Association (1995)》2013,63(8):1481-1500
ABSTRACT We have studied the possible association of daily mortality with ambient pollutant concentrations (PM10, CO, O3, SO2, NO2, and fine [PM2 5] and coarse PM) and weather variables (temperature and dew point) in the Pittsburgh, PA, area for two age groups—less than 75, and 75 and over—for the 3-year period of 1989-1991. Correlation functions among pollutant concentrations show important seasonal dependence, and this fact necessitates the use of seasonal models to better identify the link between ambient pollutant concentrations and daily mortality. An analysis of the seasonal model results for the younger-age group reveals significant multicollinearity problems among the highly correlated concentrations of PM10, CO, and NO2 (and O3 in spring and summer), and calls into question the rather consistent results of the single- and multi-pollutant non-seasonal models that show a significant positive association between PM10 and daily mortality. For the older-age group, dew point consistently shows a significant association with daily mortality in all models. Collinearity problems appear in the multi-pollutant seasonal and non-seasonal models such that a significant, positive PM10 coefficient is accompanied by a significant, negative coefficient of another ambient pollutant, and the identity of this other pollutant changes with season. The PM25 data set is half that of PM10. Identical-model runs for both data sets reveal instability in the pollutant coefficients, especially for the younger age group. The concern for the instability of the pollutant coefficients due to a small signal-to-noise ratio makes it impossible to ascertain credibly the relative associations of the fine- and coarse-particle modes with daily mortality. In this connection, we call for caution in the interpretation of model results for causal inference when the models use fully or partially estimated PM values to fill large data gaps. 相似文献
253.
Total mercury contents from both abiotic and biological compartments within several estuaries from Argentina have been studied since the 1980s. The assessment of mercury occurrence in surface sediments, suspended particulate matter and crab and fish species from Mar Chiquita coastal lagoon, Bahía Blanca estuary and Samborombón Bay (in La Plata river estuary) are included in the present study. All samples were analyzed through Cold Vapor-Atomic Absorption Spectroscopy, following internationally standardized methods. In all cases analytical quality was checked against international reference materials. During the 1980s, Hg contents in sediments and SPM, as well as in edible fish species from Bahía Blanca estuary were significantly higher (p<0.01) than those of the 1990s and 2000s, and the large industrial nucleus located in the northern margin of this estuary was elsewhere identified as the main source of this metal. A permanent monitoring program carried out in 1986 and that is being implemented up to the present has demonstrated that Hg concentration values have significantly decreased (p<0.01) compared to the values of the 1980s. Both, Mar Chiquita coastal lagoon and Samborombón Bay have intermediate mercury levels in their biological compartments. In both cases, the possible occurrence of remote sources of this metal was considered. Even though, Hg values as determined in sediments and suspended particulate matter from Samborombón Bay were the highest ones for the whole analyzed period. Both mercury bioaccumulation and biomagnification processes were evaluated in the studied estuaries, as well as the potential qualification of estuarine foodstuffs for human consumption. 相似文献
254.
Landscape-level ecological regions: Linking state-level ecoregion frameworks with stream habitat classifications 总被引:6,自引:0,他引:6
Regionalization is a form of spatial classification, where boundaries are drawn around areas that are relatively homogeneous in landscape characteristics. The process of delineating ecological regions, or ecoregions, includes the analysis of ecosystem structure. To date, ecoregions have been developed at national and state scales for research and resource management. Stream classification is another method to order the variability of aquatic habitats that spans spatial scales from microhabitat to valley segment. In this study, landscape-level ecoregions are developed for the upper Grande Ronde River basin in northeastern Oregon, 3000 sq km in area. The ecoregion framework presented here is proposed to bridge the gap between stream habitat and state-level ecoregion classifications. Classification at this scale is meant to address issues of management at local scales: to aid in sampling design, in extrapolation of the results of site-specific studies, and in the development of best management practices that are more predictive of ecosystem response than current methods. 相似文献
255.
Rissato SR Galhiane MS Ximenes VF de Andrade RM Talamoni JL Libânio M de Almeida MV Apon BM Cavalari AA 《Chemosphere》2006,65(11):1949-1958
Detailed analyses of persistent organic pollutants (POPs) such as organochlorine pesticides (OCPs), hexachlorocyclohexane (HCH) isomers (HCHs), dichlorodiphenyltrichloro ethane (DDT) and its metabolites (DDTs) and congeners of polychlorinated biphenyls (PCBs) in soil and surface water from the northeastern São Paulo, Brazil allowed the evaluation of the contamination status, distribution and possible pollution sources. The pesticides and PCBs demonstrated markedly different distributions, reflecting different agricultural, domestic and industrial usage in each region studied. The ranges of HCH, DDT, and PCBs concentrations in the soil samples were 0.05–0.92, 0.12–11.01, 0.02–0.25 ng g−1 dry wt, respectively, and in the surface water samples were 0.02–0.6, 0.02–0.58 and 0.02–0.5 ng l−1, respectively. Overall elevated levels of DDT and PCB were recorded in region 2, a site very close to melting, automotive batteries industries, and agricultural practice regions. High ratios of metabolites of DDT to DDT isomers revealed the recent use of DDT in this environment. The sources of contamination are closely related to human activities, such as domestic and industrial discharge, street runoff, agricultural pesticides and soil erosion, due to deforestation as well as atmospheric transport. 相似文献
256.
257.
Leal Filho Walter Price Elizabeth Wall Tony Shiel Chris Azeiteiro Ulisses M. Mifsud Mark Brandli Luciana Farinha Carla Sofia Caeiro Sandra Salvia Amanda Lange Vasconcelos Claudio Ruy de Sousa Luiza Olim Pace Paul Doni Federica Veiga Avila Lucas Fritzen Bárbara LeVasseur Todd Jared 《Environment, Development and Sustainability》2021,23(8):11257-11278
Environment, Development and Sustainability - The COVID-19 pandemic has caused a global crisis, one which also influences the ways sustainability is being taught at universities. This paper... 相似文献
258.
Lavorel Sandra Grigulis Karl Leitinger Georg Kohler Marina Schirpke Uta Tappeiner Ulrike 《Regional Environmental Change》2017,17(8):2251-2264
Regional Environmental Change - Land use and spatial patterns which reflect social-ecological legacies control ecosystem service (ES) supply. Yet, temporal changes in ES bundles associated with... 相似文献
259.
260.
Macías-Quiroga Iván F. Henao-Aguirre Paula A. Marín-Flórez Alexander Arredondo-López Sandra M. Sanabria-González Nancy R. 《Environmental science and pollution research international》2021,28(19):23791-23811
Environmental Science and Pollution Research - Advanced oxidation processes (AOPs) constitute a developing area of particular interest for researchers in different fields due to their broad range... 相似文献