In vivo distribution and fractionation of indium in rats after subcutaneous and oral administration of [(114m)In]InAs

Two in vivo experiments were carried out in this study. In the first experiment five rats were given two subcutaneous injections of [(114m)In]InAs. Major sites of accumulation were spleen, liver and kidney. The intracellular distribution of indium was examined by differential centrifugation. The cytoplasmic fraction contained most of the indium activity followed by the mitochondrial fraction. Both outcomes are in close agreement with the results obtained in previous studies. Chromatographic separations on a preparative size exclusion column were carried out. It was shown that indium was mostly bound to high molecular mass compounds in serum and in the cytoplasmic fraction of spleen, liver and kidney. In a second experiment five rats were given four oral doses of [(114m)In]InAs over a short period. Prior to this experiment the in vitro solubility of cold InAs in simulated gastric fluid (SGF) and simulated intestinal fluid (SIF) was determined using graphite furnace atomic absorption spectroscopy. In the case of the SGF only 1.3% of an InAs suspension dissolved after 48 hours incubation at 37 degrees C. InAs was not soluble in SIF. Uptake of InAs after oral administration was minimal (<1%). Due to incomplete removal of traces of [(114m)In]InAs from the gastrointestinal tract, it was impossible to calculate accurately the in vivo distribution over the different organs. As the uptake and consequently the activity in the organs were very low, no further chromatographic separations could be carried out. Considering this very low uptake, it can be concluded that InAs will not accumulate in the body after oral exposure.     

Sources of fine particles in the South Coast area,California

PM_2.5 (particulate matter less than 2.5 μm in aerodynamic diameter) speciation data collected between 2003 and 2005 at two United State Environmental Protection Agency (US EPA) Speciation Trends Network monitoring sites in the South Coast area, California were analyzed to identify major PM_2.5 sources as a part of the State Implementation Plan development. Eight and nine major PM_2.5 sources were identified in LA and Rubidoux, respectively, through PMF2 analyses. Similar to a previous study analyzing earlier data (Kim and Hopke, 2007a), secondary particles contributed the most to the PM_2.5 concentrations: 53% in LA and 59% in Rubidoux. The next highest contributors were diesel emissions (11%) in LA and Gasoline vehicle emissions (10%) in Rubidoux. Most of the source contributions were lower than those from the earlier study. However, the average source contributions from airborne soil, sea salt, and aged sea salt in LA and biomass smoke in Rubidoux increased.To validate the apportioned sources in this study, PMF2 results were compared with those obtained from EPA PMF (US EPA, 2005). Both models identified the same number of major sources and the resolved source profiles and contributions were similar at the two monitoring sites. The minor differences in the results caused by the differences in the least square algorithm and non-negativity constraints between two models did not affect the source identifications.     

Conceptual Frameworks and Methods for Advancing Invasion Ecology

Invasion ecology has much advanced since its early beginnings. Nevertheless, explanation, prediction, and management of biological invasions remain difficult. We argue that progress in invasion research can be accelerated by, first, pointing out difficulties this field is currently facing and, second, looking for measures to overcome them. We see basic and applied research in invasion ecology confronted with difficulties arising from (A) societal issues, e.g., disparate perceptions of invasive species; (B) the peculiarity of the invasion process, e.g., its complexity and context dependency; and (C) the scientific methodology, e.g., imprecise hypotheses. To overcome these difficulties, we propose three key measures: (1) a checklist for definitions to encourage explicit definitions; (2) implementation of a hierarchy of hypotheses (HoH), where general hypotheses branch into specific and precisely testable hypotheses; and (3) platforms for improved communication. These measures may significantly increase conceptual clarity and enhance communication, thus advancing invasion ecology.     

Management of natural hazards in Europe: The role of spatial planning in selected EU member states

This paper presents the results of an assessment made as a part of the research project, Applied Multi-Risk Mapping of Natural Hazards for Impact Assessment (ARMONIA). The aim was to identify which aspects in the so-called disaster management cycle are covered by spatial planning in planning practice in the European Union's member states of Finland, France, Germany, Greece, Italy, Poland, Spain and the UK. In contrast to the initial hypothesis, the analysis of planning practice has shown that the role of spatial planning in risk assessment and management in many ways has been overestimated. The results have shown that spatial planning is only one of many actors in risk management and that it is, in general, not involved in risk assessment. Further, multi-risk assessment approaches are not used in planning practice, risk indicators are hardly used and vulnerability indicators are not at all used. The paper will interpret these surprising results and will answer the question of the role of spatial planning in natural risk assessment and management.     

Spatial differences in outdoor PM10 mass and aerosol composition in Mexico City

Twenty-five MiniVol samplers were operated throughout the Mexico City metropolitan region from February 22 through March 22, 1997, to evaluate the variability of PM10 concentrations and composition. The highest PM10 concentrations were found in neighborhoods with unpaved or dirty roads, and elements related to crustal material were the main cause of differences from nearby (<200 m) monitors that were not adjacent to the roadbed. SO4(2-) concentrations were homogeneous across the city. SO4(2-) measured at the city boundaries was about two-thirds of the concentrations measured within the urbanized area, indicating that most SO4(2-) is of regional origin. Elemental carbon (EC) and organic carbon (OC) concentrations were highly variable, with higher concentrations in areas that had high diesel traffic and older vehicles. Spatial correlations among PM10 concentrations were high, even though absolute concentrations were variable, indicating a common effect of meteorology on the concentration or dispersion of local emissions.     

Baseline ambient gaseous ammonia concentrations in the Four Corners area and eastern Oklahoma, USA

Ambient ammonia monitoring using Ogawa passive samplers was conducted in the Four Corners area and eastern Oklahoma, USA during 2007. The resulting data will be useful in the multipollutant management of ozone, nitrogen oxides, and visibility (atmospheric regional haze) in the Four Corners area, an area with growing oil/gas production and increasing coal-based power plant construction. The passive monitoring data also add new ambient ammonia concentration information for the U.S. and will be useful to scientists involved in present and future visibility modeling exercises. Three week integrated passive ammonia samples were taken at five sites in the Four Corners area and two sites in eastern Oklahoma from December, 2006 through December, 2007 (January, 2008 for two sites). Results show significantly higher regional background ammonia concentrations in eastern Oklahoma (1.8 parts per billion (ppb) arithmetic mean) compared to the Four Corners area (0.2 ppb arithmetic mean). Annual mean ammonia concentrations for all Four Corners area sites for the 2007 study ranged from 0.2 ppb to 1.5 ppb. Peak ambient ammonia concentrations occurred in the spring and summer in both areas. The passive samplers deployed at the Stilwell, Oklahoma site compared favorably with other passive samplers and a continuous ammonia monitoring instrument.     

Biomanipulation of hypereutrophic ponds: when it works and why it fails

Phytoplankton, zooplankton, submerged vegetation and main nutrients have been monitored in 48 eutrophic ponds from the Brussels Capital Region (Belgium) between 2005 and 2008. Nine ponds have been biomanipulated in order to improve their ecological quality and prevent the occurrence of noxious cyanobacterial blooms. The 4-year study of a large number of ponds allowed identification of the factors having the strongest influence on phytoplankton growth. Continuous monitoring of the biomanipulated ponds allowed the significance of changes caused by biomanipulation to be tested as well as the main reasons of biomanipulation successes and failures to be elucidated. The main factors controlling phytoplankton in the ponds studied appeared to be grazing by large cladocerans and inhibition of phytoplankton growth by submerged vegetation. Biomanipulation resulted in a significant decrease in phytoplankton biomass in general and biomass of bloom-forming cyanobacteria in particular that were associated with a significant increase in large Cladocera density and size. In six out of nine ponds biomanipulation resulted in the restoration of submerged vegetation. The maintenance of the restored clearwater state in the biomanipulated ponds was strongly dependent on fish recolonisation and nutrient level. In the absence of fish, the clearwater state could be maintained by submerged vegetation or large zooplankton grazing alone. In case of fish recolonisation, restoration of extensive submerged vegetation could buffer, to a considerable degree, the effect of fish except for ponds with high nutrient levels.     

Seasonal variation in the levels of organohalogen compounds in herring (Clupea harengus) from the Norwegian Sea

The Norwegian spring spawning (NSS) herring is an ecologically important fish stock in the Norwegian Sea, and with a catch volume exceeding one million tons a year it is also economically important and a valuable food source. In order to provide a baseline of the levels of contaminants in this fish stock, the levels of organohalogen compounds were determined in 800 individual herring sampled at 29 positions in the Norwegian Sea and off the coast of Norway. Due to seasonal migration, the herring were sampled where they were located during the different seasons. Concentrations of dioxins and dioxin-like PCBs, non-dioxin-like PCBs (PCB₇) and PBDEs were determined in fillet samples of individual herring, and found to be relatively low, with means (min-max) of 0.77 (0.24-3.5) ng TEQ kg⁻¹ wet weight (ww), 5.0 (1.4-24) μg kg⁻¹ ww and 0.47 (0.091-3.1) μg kg⁻¹ ww, respectively. The concentrations varied throughout the year due to the feeding- and spawning cycle: Starved, pre-spawning herring caught off the Norwegian coast in January-February had the highest levels and those caught in the Norwegian Sea in April-June, after further starvation and spawning, had the lowest levels. These results show that the concentrations of organohalogen compounds in NSS herring are relatively low and closely tied to their physiological condition, and that in the future regular monitoring of NSS herring should be made in the spawning areas off the Norwegian coast in late winter.