存在截渗墙情况下地下咸水恢复的优化方案

本文首先分析了咸水分布区的自然地理和水文地质条件，然后对研究区的水文地质条件进行了概化，建立了相应的地下水水量和水质的数值模型，最后通过地下水模拟软件Visual—MODFLOW3.1对存在截渗墙情况下的不同咸水恢复方案进行了数值分析。研究结果表明。单纯的抽水方案对于高浓度咸水的去除非常有效，但是低浓度咸水残留量较大；抽水——注水方案对高低浓度的去除效果都比较好；而抽水优化方案对高浓度和低浓度的咸水的去除更加经济、快速和彻底。     

如何浅开谈展石环油境石应化企急工业作

根据石化企业环境应急工作面临的任务和国内外发展趋势,对企业的环境应急现状和存在问题进行了分析和评价,论述了开展环境应急工作的必要性和紧迫性,探讨了石化企业开展环境应急工作的指导思想和方法。     

丽江古城水环境现状与调控对策研究

水环境是丽江世界文化遗产地生态地质环境的重要组成部分。由于丽江城市化进程加快，对水环境保护不力，导致古城水污染加剧、水资源量衰减、景观生态用水不足和景观水质下降。通过强化水环境研究，加强水环境立法，进行水生态环境综合治理；实施以调剂古城周边地下泉水为主，拉市海调水为辅的丽江古城景观调水方案，可保护丽江古城水环境，为丽江古城世界文化遗产地的可持续发展提供保证。     

浅谈水质在线监控中遥感技术的应用

空间信息技术以及计算机技术的发展，给环境监控提供了先进、快速和科学的方法。其中，遥感技术由于能够快速、宏观地获得所监控区域的数据，近年来已逐渐成为环境监控系统中的重要技术手段。遥感信息是被控区域的电磁辐射能量及其结构特征与时空状态在遥感图像上的表现。今后，遥感技术、在线监控系统和地理信息系统等多种信息处理工具的结合将是环境信息监控系统发展的主要方向。     

Nitrogen removal from landfill leachate via ex situ nitrification and sequential in situ denitrification

Ex situ nitrification and sequential in situ denitrification represents a novel approach to nitrogen management at landfills. Simultaneous ammonia and organics removal was achieved in a continuous stirred tank reactor (CSTR). The results showed that the maximum nitrogen loading rate (NLR) and the maximum organic loading rate (OLR) was 0.65 g N l^?1 d^?1 and 3.84 g COD l^?1 d^?1, respectively. The ammonia and chemical oxygen demand (COD) removal was over 99% and 57%, respectively. In the run of the CSTR, free ammonia (FA) inhibition and low dissolved oxygen (DO) were found to be key factors affecting nitrite accumulation. In situ denitrification was studied in a municipal solid waste (MSW) column by recalculating nitrified leachate from CSTR. The decomposition of MSW was accelerated by the recirculation of nitrified leachate. Complete reduction of total oxidized nitrogen (TON) was obtained with maximum TON loading of 28.6 g N t^?1 TS d^?1 and denitrification was the main reaction responsible. Additionally, methanogenesis inhibition was observed while TON loading was over 11.4 g N t^?1 TS d^?1 and the inhibition was enhanced with the increase of TON loading.     

The fragmentation patterns of maternal plasma cell-free DNA and its applications in non-invasive prenatal testing

The discovery of cell-free DNA (cfDNA) in maternal plasma has opened up new promises for the development of non-invasive prenatal testing (NIPT). Application of cfDNA in NIPT of fetus diseases and abnormalities is restricted by the low amount of fetal DNA molecules in maternal plasma. Fetus-derived cfDNA in maternal plasma are shorter than maternal DNA, thus leveraging the maternal and fetus-derived cfDNA molecules size difference has become a novel and more accurate method for NIPT. However, multiple biological properties such as size distribution of plasma DNA, proportion of fetal-derived DNA and methylation levels in maternal plasma across different gestational ages still remain largely unknown. Further insights into the size distribution and fragmentation pattern of circulating plasma cfDNA will shed light on the origin and fragmentation mechanisms of cfDNA during physiological and pathological processes in prenatal diseases and enhance our ability to take the advantage of plasma cfDNA as a molecular diagnostic tool. In the review, we start by summarizing the research techniques for the determination of the fragmentation profiles of cfDNA in maternal plasma. We then summarize the main progress and findings in size profiles of maternal plasma cfDNA and cffDNA. Finally, we discuss the potential diagnostic applications of plasma cfDNA size profiling.     

Discordant results between fetal karyotyping and non-invasive prenatal testing by maternal plasma sequencing in a case of uniparental disomy 21 due to trisomic rescue

Uniparental disomy (UPD) is an uncommon chromosome condition, but UPD involving chromosome 21 is rarely reported. We reported here a case who had first trimester screening test for Down syndrome, chorionic villus sampling for fetal karyotyping, quantitative fluorescence polymerase chain reaction (QF-PCR), as well as non-invasive prenatal testing (NIPT) by maternal plasma sequencing. There were discordant results between fetal karyotyping and NIPT due to UPD 21combined with confined placental mosaicism of trisomy 21. This demonstrated that it is possible to detect placental mosaicism by NIPT, but further studies are required to confirm its sensitivity. Therefore, all positive NIPT results must be confirmed by conventional invasive test and karyotyping. QF-PCR has the additional benefit in diagnosing UPD. © 2013 John Wiley & Sons, Ltd.