Über die Wirkung von N-(4-Methyl-benzolsulfonyl)-N′-butyl-harnstoff auf die Glukose-6-Phosphatase der Leber

The Science of Nature -     

Prenatal diagnosis and outcomes of five cases of mosaicism for an isochromosome of 20q

Five cases of mosaicism for an isochromosome of 20q have been detected from a total of 50 000 cases analysed for prenatal diagnosis by amniocentesis. Karyotypes were designated mos 46,X_/46,X_,i(20q). In all cases, the abnormal cell line was detected in more than one primary culture, thus fulfilling the criterion for true (level III) mosaicism. Indications for prenatal diagnosis were parental anxiety (two cases), low maternal serum alpha-fetoprotein (AFP) (two cases), and high maternal serum AFP (one case). Level II ultrasounds on all five fetuses were normal, and the abnormal cell line was never detected in fetal blood and/or cord blood. All five pregnancies were continued and had normal outcomes, with birth weights ranging from 2.4 to 3.8 kg. The development of all five children has been normal, with the oldest child in the study now 4 years of age. We suggest that the abnormal cell line in each case was of extrafetal origin, and that this may be one of the more common examples of this phenomenon, occurring in approximately 1/10000 prenatal diagnoses. Mosaicism i(20q) may have been missed in the past because of the higher resolution necessary to detect this subtle change.     

Der Einfluß von Verbraucher und Handel auf die Qualität landwirtschaftlicher Produkte und Lebensmittel

The modern consumer is very much interested in healthy food. The reason is that a special group of consumers is focusing more and more attention on health and nutrition problems. Further, there is increased emphasis on education in food science at universities as well as polytechnics. For some years worldwide dietary goals are published with the intention to reduce nutrition-based sickness. For the first time in our nutrition report 1988, clear proposals for optimal nutrition were formulated.