Is Abolitionism Guilty of Racism? A Reply to Cordeiro-Rodrigues

Gary Francione is an abolitionist: he maintains that we ought to abolish the institutions and practices that support the exploitation of animals. He also believes that veganism is the “moral baseline”—that is, he thinks it’s morally required of nearly everyone in the developed world, and many beyond it. Luis Cordeiro-Rodrigues claims that abolitionism is guilty of racism, albeit “racism without racists.” I contend that his arguments for this conclusion aren’t successful.     

The Consideration of Sustainability Aspects in Transport Infrastructure Related Policies,Plans and Programmes: A Comparative Analysis of North West England,Noord-Holland and Brandenburg-Berlin

This paper is based on research conducted in 1997 and 1998 at the EIA Centre, University of Manchester. It examines the extent to which transport infrastructure related policies, plans and programmes (PPPs) in the three EU regions of North West England, the provincie (administrativeregion) of Noord-Hollandand the engerer Verflechtungsraum (EVR, planning region) of Brandenburg-Berlinconsider (environmental) sustainability issues in the form of objectives, targets and related options/measures for action. Furthermore, the role strategic environmental assessment (SEA) appears to play in this context is elaborated. The analytical framework for comparison is based on the sustainable development strategy of the European Commission, the Fifth Action Programme (Commission of the European Communities, 1993).     

Mineral licks: motivational factors for visitation and accompanying disease risk at communal use sites of elk and deer

Free-ranging cervids acquire most of their essential minerals through forage consumption, though occasionally seek other sources to account for seasonal mineral deficiencies. Mineral sources occur as natural geological deposits (i.e., licks) or as anthropogenic mineral supplements. In both scenarios, these sources commonly serve as focal sites for visitation. We monitored 11 licks in Rocky Mountain National Park, north-central Colorado, using trail cameras to quantify daily visitation indices (DVI) and soil consumption indices (SCI) for Rocky Mountain elk (Cervus elaphus) and mule deer (Odocoileus hemionus) during summer 2006 and documented elk, mule deer, and moose (Alces alces) visiting licks. Additionally, soil samples were collected, and mineral concentrations were compared to discern levels that explain rates of visitation. Relationships between response variables; DVI and SCI, and explanatory variables; elevation class, moisture class, period of study, and concentrations of minerals were examined. We found that DVI and SCI were greatest at two wet, low-elevation licks exhibiting relatively high concentrations of manganese and sodium. Because cervids are known to seek Na from soils, we suggest our observed association of Mn with DVI and SCI was a likely consequence of deer and elk seeking supplemental dietary Na. Additionally, highly utilized licks such as these provide an area of concentrated cervid occupation and interaction, thus increasing risk for environmental transmission of infectious pathogens such as chronic wasting disease, which has been shown to be shed in the saliva, urine, and feces of infected cervids.     

The cytotoxicity of nici2 for mammalian cells in culture†

The effects of NiCl₂ were studied in two human cell lines, HeLa and diploid embryonic fibroblasts as well as in V79 Chinese hamster cells and in L‐A mouse fibroblasts. NiCl₂ produces a dose‐dependent depression of proliferation, mitotic rate, and viability, accompanied by an increasing release of lactic dehydrogenase and stimulation of lactic acid production. The plating efficiency is reduced, as are DNA and protein synthesis and, to a lesser degree, RNA synthesis.

The cytotoxicity of NiCl₂ is comparable in degree to those of PbCl₂ and MnCl₂, but is weaker than those of HgCl₂ and CdCl₂. However, the different sensitivities of different cell lines must also be considered.

NiCl₂ effects are more severe in serum‐free medium than in medium containing serum or serum albumin indicating that serum constituents, notably albumin, bind the metal effectively and inhibit cellular uptake; this confirms earlier reports on the serum binding and slow uptake of NiCl₂.

Synchronized cells are most sensitive in the Gl and early S phases of the cell cycle. In the Painter test the depression of DNA synthesis persists following cessation of exposure to NiCI₂. These findings contribute an explanation for the known genotoxic effects of nickel.     

Eutrophication alters social preferences in three-spined sticklebacks (Gasterosteus aculeatus)

Algae blooms, which can be caused by eutrophication, drastically influence the ecology and behaviour of aquatic organisms. Such impact is often demonstrated in the context of mate choice and predator–prey interactions. In contrast, the influence of increased turbidity on social behaviour is less well understood, although it may have strong influence, at both the level of the individual and the population. We aimed to address this gap in our knowledge by using the well-described preference of three-spined sticklebacks (Gasterosteus aculeatus) to shoal with the larger of two shoals as model behaviour. In our experiments focal fish had the choice between two shoals of different sizes, either in clear or in turbid water containing green algae. Fish in clear water spent significantly more time near the larger shoal, while fish in algae water showed no significant preferences. Furthermore, fish tested in clear water changed more often between the shoals than fish tested in algae water. These results indicate that eutrophication-induced algae blooms have the potential to alter social decisions of sticklebacks. Such changes of social decisions do not only influence the behaviour of individuals, furthermore it might influence entire populations. This might eventually lead to changes of the structure of the social system.     

The zebrafish embryo model in environmental risk assessment—applications beyond acute toxicity testing

BACKGROUND, AIM, AND SCOPE: The use of fish embryos is not regulated by current legislations on animal welfare and is therefore considered as a refinement, if not replacement of animal experiments. Fish embryos represent an attractive model for environmental risk assessment of chemicals since they offer the possibility to perform small-scale, high-throughput analyses. MAIN FEATURES: Beyond their application for determining the acute toxicity, fish embryos are also excellent models for studies aimed at the understanding of toxic mechanisms and the indication of possible adverse and long-term effects. Therefore, we have reviewed the scientific literature in order to indicate alternative applications of the fish embryo model with focus on embryos of the zebrafish. RESULTS AND DISCUSSIONS: The analysis of the mode of action is important for the risk assessment of environmental chemicals and can assist in indicating adverse and long-term effects. Toxicogenomics present a promising approach to unravel the potential mechanisms. Therefore, we present examples of the use of zebrafish embryos to study the effect of chemicals on gene and protein patterns, and the potential implications of differential expression for toxicity. The possible application of other methods, such as kinase arrays or metabolomic profiling, is also highlighted. Furthermore, we show examples of toxicokinetic studies (bioconcentration, ABC transporters) and discuss limitations that might be caused by the potential barrier function of the chorion. Finally, we demonstrate that biomarkers of endocrine disruption, immune modulation, genotoxicity or chronic toxicity could be used as indicators or predictors of sub-acute and long-term effects. CONCLUSIONS: The zebrafish embryo represents a model with an impressive range of possible applications in environmental sciences. Particularly, the adaptation of molecular, system-wide approaches from biomedical research is likely to extend its use in ecotoxicology. RECOMMENDATIONS AND PERSPECTIVES: Challenges for future research are (1) the identification of further suitable molecular markers as indicators of the mode of action, (2) the establishment of strong links between (molecular) effects in short-term assays in embryos and long-term (toxic) effects on individuals, (3) the definition of limitations of the model and (4) the development of tests that can be used for regulatory purposes.