Anticancer mechanisms of phytochemical compounds: focusing on epigenetic targets

Environmental Science and Pollution Research - It has recently been proven that epigenetic dysregulation is importantly involved in cell transformation and therefore induces cancerous diseases. The...     

The impact of recycled coarse aggregates obtained from waste concretes on lightweight pervious concrete properties

Environmental Science and Pollution Research - Significant environmental damage can result from the use of natural resources such as cement, aggregate, and water in concrete production. Thus, more...     

Model-based assessment of groundwater vulnerability for the Dalyan Region of southwestern Mediterranean Turkey

Regional Environmental Change - The Dalyan Region that drains into a complex lagoon system is located on the Mediterranean Sea coast of southwest Turkey. There are no large streams in the...     

Determination of Soil Erosion Risk in the Mustafakemalpasa River Basin, Turkey, Using the Revised Universal Soil Loss Equation, Geographic Information System, and Remote Sensing

Sediment transport from steep slopes and agricultural lands into the Uluabat Lake (a RAMSAR site) by the Mustafakemalpasa (MKP) River is a serious problem within the river basin. Predictive erosion models are useful tools for evaluating soil erosion and establishing soil erosion management plans. The Revised Universal Soil Loss Equation (RUSLE) function is a commonly used erosion model for this purpose in Turkey and the rest of the world. This research integrates the RUSLE within a geographic information system environment to investigate the spatial distribution of annual soil loss potential in the MKP River Basin. The rainfall erosivity factor was developed from local annual precipitation data using a modified Fournier index: The topographic factor was developed from a digital elevation model; the K factor was determined from a combination of the soil map and the geological map; and the land cover factor was generated from Landsat-7 Enhanced Thematic Mapper (ETM) images. According to the model, the total soil loss potential of the MKP River Basin from erosion by water was 11,296,063?Mg?year(-1) with an average soil loss of 11.2?Mg?year(-1). The RUSLE produces only local erosion values and cannot be used to estimate the sediment yield for a watershed. To estimate the sediment yield, sediment-delivery ratio equations were used and compared with the sediment-monitoring reports of the Dolluk stream gauging station on the MKP River, which collected data for >41?years (1964-2005). This station observes the overall efficiency of the sediment yield coming from the Orhaneli and Emet Rivers. The measured sediment in the Emet and Orhaneli sub-basins is 1,082,010?Mg?year(-1) and was estimated to be 1,640,947?Mg?year(-1) for the same two sub-basins. The measured sediment yield of the gauge station is 127.6?Mg?km(-2)?year(-1) but was estimated to be 170.2?Mg?km(-2) year(-1). The close match between the sediment amounts estimated using the RUSLE-geographic information system (GIS) combination and the measured values from the Dolluk sediment gauge station shows that the potential soil erosion risk of the MKP River Basin can be estimated correctly and reliably using the RUSLE function generated in a GIS environment.     

Evaluation of the efficiency of chlorpyrifos-ethyl remediation by Methylobacterium radiotolerans and Microbacterium arthrosphaerae using response of some biochemical biomarkers

Environmental Science and Pollution Research - This study reveals out detoxifying and antioxidant enzyme response of Gammarus pulex exposed/polluted to chlorpyrifos-ethyl insecticide before and...     

Physiopathology and effectiveness of therapeutic vaccines against human papillomavirus

Environmental Science and Pollution Research - Human papillomavirus (HPV) is a well-known sexually transmitted disorder globally. Human papillomavirus (HPV) is the 3rd most common cancer that...     

Comprehensive review on naringenin and naringin polyphenols as a potent anticancer agent

Environmental Science and Pollution Research - Though the incidence of several cancers in Western societies is regulated wisely, some cancers such as breast, lung, and colorectal cancer are...     

Monitoring metal contamination levels and fecal pollution in clam (Tapes decussatus) collected from Izmir Bay (Turkey)

The aim of this study was to monitor the heavy metal contents and fecal pollution in Tapes decussatus (carpet shell clam) from Izmir Bay (Eastern Aegean). Bivalve mollusks were sampled on January, March, July, and October 2007 in the Izmir Bay. Izmir Bay is one of the great natural bays of the Mediterranean. Concentrations of heavy metals were determined in the clams from the different seasons. Fecal coliform densities were determined to evaluate the degree of water pollution and clams’ microbiological accumulation of the classical microbial pollution indicators. The concentration of heavy metals in T. decussatus from Izmir Bay were Hg 0.044–0.13; Cd 0.026–0.24; Pb 0.38–1.2; Cr 2.3–3.7; Cu 6.4–8.4; Zn 56.0–81.8, and Ni 8.1–9.6 μg/g (dry weight). The maximum values were generally obtained in July and March except Ni. This study found that the levels of heavy metals except Cr in T. decussatus were below Spanish and European Communities legislations for shellfish as food. Microbial pollution indicators (heterotrophic bacteria and fecal coliform) were measured in T. decussatus. Maximum heterotrophic bacteria and fecal coliforms were recorded in the winter while the lowest were detected in summer.     

Prenatal diagnosis of jumping translocation involving chromosome 22 with ultrasonographic findings

We report on the prenatal diagnosis and ultrasonographic findings of a second-trimester fetus with jumping translocation involving chromosome 22. A 28-year-old gravida 2, partus 1, Turkish woman was referred for genetic counselling and ultrasonographic examination at 18 weeks' gestation because of a high risk of trisomy 21 in triple test. Prenatal ultrasonography showed tetralogy of Fallot with a diverticular dilatation of the pulmonary artery, flattened brow, complete absence of the right upper limb, hypospadias, oligodactyly (three digits) in left hand and in both feet, and hyperechogenic abdominal foci. Amniocentesis revealed a karyotype of 46,XY[4]/46,XY,−8,+ der(8),t(8;22)(q24.3;q11.21)[2]/45, XY,−22,−8,+ der(8)t(8;22)(q24.3;q11.21)[22]/45,XY,−22,−5,+ der(5)t(5;22)(q35.3;q11.21)[44]. A C-banding and FISH study with a specific centromeric probe (D14Z1/D22Z1) for chromosome 22 was made. In our case, partial monosomy for the regions 22q11.21→22pter, 8q24.3→8qter and 5q35.3→5qter may partially explain the fetal malformations. Copyright © 2005 John Wiley & Sons, Ltd.     

Anticancer properties of medicinal plants and their bioactive compounds against breast cancer: a review on recent investigations

Environmental Science and Pollution Research - Breast cancer (BC) is one of the most common and recurring diseases and the second leading cause of death in women. Despite prevention, diagnostics,...