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951.
952.
Mary C. Phelan Ph.D. Robert A. Saul Thompson A. Gailey Jr Steven A. Skinner 《黑龙江环境通报》1995,15(3):274-277
Mosaicism for the Wolf-Hirschhorn syndrome, del(4)(p16), is extremely rare and has not been reported in association with a numerical chromosome abnormality. We report the prenatal diagnosis of mosaic del(4)(p16) and non-mosaic trisomy 21 in a 16-week female fetus. The pregnancy ended in spontaneous abortion at 34 weeks secondary to fetal demise. The fetus had features of both 4p – and trisomy 21. 相似文献
953.
Prenatal counselling for fetal agenesis of the corpus callosum is difficult as the prognosis until now has been so uncertain. We have reviewed the current world English literature to provide the best probabilistic information for prospective parents. In total, there are 70 cases where the diagnosis was made prenatally. The diagnosis of apparently isolated agenesis of the corpus callosum (in the absence of other sonographically detectable anomalies) appears to carry an excellent prognosis, with an 85 per cent chance of a normal developmental outcome and a 15 per cent risk of handicap. Fetal karyotyping is recommended as there is a 1 in 10 risk of aneuploidy. If other anomalies are detected prenatally, the outcome is very poor. Termination of pregnancy is advised in these circumstances. 相似文献
954.
Forty-two open neural tube defects (NTDs) were identified in our series of 7440 amniocenteses tested between 11 and 15 weeks of gestation. Using a cut-off of ≥2.0 MOM, the detection rate for open NTDs was 95 per cent; 100 per cent each for anencephaly and spina bifida; and 78 per cent for encephalocele. Two encephaloceles had AFP levels less than 2.0 MOM and negative AChEs. Thirty-four (81 per cent) of these NTDs were tested between 13 and 15 weeks and 8 (19 per cent) before 13 weeks. There were 0.6 per cent false positives by AFP (excluding serious abnormalities and fetal death) and 0.1 per cent after AChE. The likelihood of an open NTD after an elevated AFP (≥2.0 MOM) was 24 and 77 per cent for any serious abnormality. These results, when combined with an earlier study, indicate that amniotic fluid AFP appears to be as sensitive a test for open NTDs between 13 and 15 weeks as between 16 and 20 weeks. Additional experience is necessary to determine this before 13 weeks. 相似文献
955.
Tzipora C. Falik-Borenstein MD Stuart A. Holmes Zvi Borochowitz Abi Levin A. Rosenmann Richard A. Spritz 《黑龙江环境通报》1995,15(4):345-349
We describe molecular prenatal diagnosis and carrier detection of tyrosinase-negative oculocutaneous albinism (OCA1A) in two families. In one family, we carried out DNA-based prenatal diagnosis of OCA1A. In the other family, mutation analysis and carrier detection obviated the need for prenatal diagnosis. Molecular analysis is safer and probably more accurate than fetoscopy and fetal scalp biopsy, and should become the method of first choice for prenatal diagnosis of OCA1. 相似文献
956.
Shamama Afreen Nitasha Sharma Rajiv K. Chaturvedi Ranjith Gopalakrishnan N. H. Ravindranath 《Mitigation and Adaptation Strategies for Global Change》2011,16(2):177-197
Due to large scale afforestation programs and forest conservation legislations, India’s total forest area seems to have stabilized
or even increased. In spite of such efforts, forest fragmentation and degradation continues, with forests being subject to
increased pressure due to anthropogenic factors. Such fragmentation and degradation is leading to the forest cover to change
from very dense to moderately dense and open forest and 253 km2 of very dense forest has been converted to moderately dense forest, open forest, scrub and non-forest (during 2005–2007).
Similarly, there has been a degradation of 4,120 km2 of moderately dense forest to open forest, scrub and non-forest resulting in a net loss of 936 km2 of moderately dense forest. Additionally, 4,335 km2 of open forest have degraded to scrub and non-forest. Coupled with pressure due to anthropogenic factors, climate change
is likely to be an added stress on forests. Forest sector programs and policies are major factors that determine the status
of forests and potentially resilience to projected impacts of climate change. An attempt is made to review the forest policies
and programs and their implications for the status of forests and for vulnerability of forests to projected climate change.
The study concludes that forest conservation and development policies and programs need to be oriented to incorporate climate
change impacts, vulnerability and adaptation. 相似文献
957.
N. H. Ravindranath Rajiv K. Chaturvedi N. V. Joshi R. Sukumar Jayant Sathaye 《Mitigation and Adaptation Strategies for Global Change》2011,16(2):211-227
Climate change is projected to impact forest ecosystems, including biodiversity and Net Primary Productivity (NPP). National
level carbon forest sector mitigation potential estimates are available for India; however impacts of projected climate change
are not included in the mitigation potential estimates. Change in NPP (in gC/m2/yr) is taken to represent the impacts of climate change. Long term impacts of climate change (2085) on the NPP of Indian
forests are available; however no such regional estimates are available for short and medium terms. The present study based
on GCM climatology scenarios projects the short, medium and long term impacts of climate change on forest ecosystems especially
on NPP using BIOME4 vegetation model. We estimate that under A2 scenario by the year 2030 the NPP changes by (−5) to 40% across
different agro-ecological zones (AEZ). By 2050 it increases by 15% to 59% and by 2070 it increases by 34 to 84%. However,
under B2 scenario it increases only by 3 to 25%, 3.5 to 34% and (−2.5) to 38% respectively, in the same time periods. The
cumulative mitigation potential is estimated to increase by up to 21% (by nearly 1 GtC) under A2 scenario between the years
2008 and 2108, whereas, under B2 the mitigation potential increases only by 14% (646 MtC). However, cumulative mitigation
potential estimates obtained from IBIS—a dynamic global vegetation model suggest much smaller gains, where mitigation potential
increases by only 6% and 5% during the period 2008 to 2108. 相似文献
958.
959.
Introduction
This study examined the impact of the British Petroleum (BP) Baker Panel Report, reviewing the March 2005 BP-Texas City explosion, on the field of process safety.Method
Three hundred eighty-four subscribers of a process safety listserv responded to a survey two years after the BP Baker Report was published.Results
Results revealed respondents in the field of process safety are familiar with the BP Baker Report, feel it is important to the future safety of chemical processing, and believe that the findings are generalizable to other plants beyond BP-Texas City. Respondents indicated that few organizations have administered the publicly available BP Process Safety Culture Survey. Our results also showed that perceptions of contractors varied depending on whether respondents were part of processing organizations (internal perspective) or government or consulting agencies (external perspective).Conclusions
This research provides some insight into the beliefs of chemical processing personnel regarding the transportability and generalizability of lessons learned from one organization to another.Impact on Industry
This study has implications for both organizational scientists and engineers in that it reveals perceptions about the primary mechanism used to share lessons learned within one industry about one major catastrophe (i.e., investigation reports). This study provides preliminary information about the perceived impact of a report such as this one. 相似文献960.
Evaporating liquid flow in a channel (An integral model based on shallow water flow approximation) 总被引:1,自引:0,他引:1
Phani K. Raj 《Journal of Loss Prevention in the Process Industries》2011,24(6):886-899
Liquefied Natural Gas (LNG) storage facilities generally include channels to convey potential spills of the liquid to an impoundment. There is increasing concern that dispersion of vapors generated by flow of LNG in a channel may lead to higher than limit vapor concentrations for safety at site boundary from channels that may be close to the dike walls. This issue is of recent concern to regulatory agencies, because the calculation of vapor hazard distance(s) from LNG flow in a channel is not required under existing LNG facility siting standards or regulations.An important parameter that directly affects the calculated LNG vapor dispersion distance is the source strength (i.e., the rate of vaporization of LNG flow from the wetted channel surfaces, as a function of spatial position and time). In this paper a model is presented which considers the variation of the depth of the flowing LNG with spatial location and time, and calculates the spatial and temporal dependence of the mass rate of vapor generation. Self similar profiles for the spatial variation of the thermal boundary layer in the liquid wetted wall and liquid depth variation are assumed. The variation with time of the location of the liquid spread front and the evaporation rate are calculated for the case of a constant LNG spill rate into a rectangular channel. The effects of two different channel slopes are evaluated. Details of the results and their impact on dispersion distances are discussed. 相似文献