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941.
Laura Y. Sifuentes Sonia L. M. Fankem Kelly Reynolds Akrum H. Tamimi Charles P. Gerba David Koenig 《Food and environmental virology》2017,9(1):14-19
The purpose of this study was to validate the use of adenosine triphosphate (ATP) for evaluating hygiene intervention effectiveness in reducing viral dissemination in an office environment. The bacterial virus MS-2 was used to evaluate two scenarios, one where the hand of an individual was contaminated and another where a fomite was contaminated. MS-2 was selected as a model because its shape and size are similar to many human pathogenic viruses. Two separate experiments were conducted, one in which the entrance door push plate was inoculated and the other in which the hand of one selected employee was inoculated. In both scenarios, 54 selected surfaces in the office were tested to assess the dissemination of the virus within the office. Associated surface contamination was also measured employing an ATP meter. More than half of the tested hands and surfaces in the office were contaminated with MS-2 within 4 h. Next, an intervention was conducted, and each scenario was repeated. Half of the participating employees were provided hand sanitizer, facial tissues, and disinfecting wipes, and were instructed in their use. A significant (p < 0.05) reduction was observed in the number of surfaces contaminated with virus. This reduction in viral spread was evident from the results of both viral culture and the surface ATP measurements, although there was no direct correlation between ATP measurements with respect to viral concentration. Although ATP does not measure viruses, these results demonstrate that ATP measurements could be useful for evaluating the effectiveness of hygiene interventions aimed at preventing viral spread in the workplace. 相似文献
942.
Christine Susan Fagnant Alexandra Lynn Kossik Nicolette Angela Zhou Liliana Sánchez-Gonzalez Jill Christin Falman Erika Karen Keim Yarrow Linden Alana Scheibe Kilala Sayisha Barnes Nicola Koren Beck David S. Boyle John Scott Meschke 《Food and environmental virology》2017,9(4):383-394
Environmental surveillance of poliovirus (PV) and other non-enveloped viruses can help identify silent circulation and is necessary to certify eradication. The bag-mediated filtration system is an efficient method to filter large volumes of environmental waters at field sites for monitoring the presence of viruses. As filters may require long transit times to off-site laboratories for processing, viral inactivation or overgrowth of bacteria and fungi can interfere with virus detection and quantification (Miki and Jacquet in Aquatic Microb Ecol 51(2):195–208, 2008). To evaluate virus survival over time on ViroCap? filters, the filters were seeded with PV type 1 (PV1) and/or MS2 and then dosed with preservatives or antibiotics prior to storage and elution. These filters were stored at various temperatures and time periods, and then eluted for PV1 and MS2 recovery quantification. Filters dosed with the preservative combination of 2% sodium benzoate and 0.2% calcium propionate had increased virus survival over time when stored at 25 °C, compared to samples stored at 25 °C with no preservatives. While elution within 24 h of filtration is recommended, if storage or shipping is required then this preservative mixture can help preserve sample integrity. Addition of an antibiotic cocktail containing cephapirin, gentamicin, and Proclin? 300 increased recovery after storage at 4 and 25 °C, when compared to storage with no antibiotics. The antibiotic cocktail can aid sample preservation if access to appropriate antibiotics storage is available and sample cold chain is unreliable. This study demonstrated that the use of preservatives or antibiotics is a simple, cost-effective method to improve virus detection from ViroCap cartridge filters over time. 相似文献
943.
Leena Maunula M. Rönnqvist R. Åberg J. Lunden M. Nevas 《Food and environmental virology》2017,9(3):358-359
944.
In this Concepts & Synthesis paper, we expand the definition of chronodisruption in humans by proposing that it can be operationalized as the split nexus of internal and external times. With this premise, we suggest how chronotype may be used as a temporal marker (chronomarker) of exposure to chronodisruption in studies of cancer, and beyond, offer cancer risk predictions for observational research on the basis of a chronotype-related hypothesis and corollary, and point to first empirical data in humans. In an a priori way, we examine possible outcomes and perspectives for preventive measures following from our rationale and the suggested chronobiology-driven studies and close with overall advances of chronodisruption research. 相似文献
945.
Christopher D. Pull William O. H. Hughes Mark J. F. Brown 《Die Naturwissenschaften》2013,100(12):1125-1136
Pathogens exert a strong selection pressure on organisms to evolve effective immune defences. In addition to individual immunity, social organisms can act cooperatively to produce collective defences. In many ant species, queens have the option to found a colony alone or in groups with other, often unrelated, conspecifics. These associations are transient, usually lasting only as long as each queen benefits from the presence of others. In fact, once the first workers emerge, queens fight to the death for dominance. One potential advantage of co-founding may be that queens benefit from collective disease defences, such as mutual grooming, that act against common soil pathogens. We test this hypothesis by exposing single and co-founding queens to a fungal parasite, in order to assess whether queens in co-founding associations have improved survival. Surprisingly, co-foundresses exposed to the entomopathogenic fungus Metarhizium did not engage in cooperative disease defences, and consequently, we find no direct benefit of multiple queens on survival. However, an indirect benefit was observed, with parasite-exposed queens producing more brood when they co-founded, than when they were alone. We suggest this is due to a trade-off between reproduction and immunity. Additionally, we report an extraordinary ability of the queens to tolerate an infection for long periods after parasite exposure. Our study suggests that there are no social immunity benefits for co-founding ant queens, but that in parasite-rich environments, the presence of additional queens may nevertheless improve the chances of colony founding success. 相似文献
946.
M. M. P. B. Fuentes M. R. Fish J. A. Maynard 《Mitigation and Adaptation Strategies for Global Change》2012,17(1):51-63
Climate change poses a serious threat to sea turtles (Cheloniidae) as their terrestrial reproductive phase is only successful
within a limited range of environmental and physical conditions. These conditions are likely to become less optimal as climate
change progresses. To date, management and conservation of sea turtles has focused almost entirely on non-climatic stressors,
due at least in part to practitioners not knowing what strategies to take and the feasibility and risks of potential strategies.
To aid the management of sea turtles in a changing environment, we identified management strategies via a focus workshop and
surveys to mitigate the impacts of climate change to the terrestrial reproductive phase of sea turtles. The effectiveness,
ecological risks and potential social and logistical constraints associated with implementing each of the identified management
strategies is discussed. Twenty management strategies were identified; strategies varied from habitat protection to more active
and direct manipulation of nests and the nesting environment. Based on our results, we suggest a three-pronged approach to
sea turtle conservation in light of climate change, where managers and researchers should: 1) enhance sea turtle resilience
to climate change by mitigating other threats; 2) prioritise implementing the ‘no regret’ and ‘reversible’ management strategies
identified here; and 3) fill the knowledge gaps identified to aid the trial and implementation of the potential strategies identified here. By combining these three approaches our collective toolkit of sea turtle management strategies
will expand, giving us an array of viable approaches to implement as climate change impacts become more extreme. 相似文献
947.
Dimensional analysis and scaling in mechanical mixing for fabrication of metal matrix nanocomposites
S. García-Rodríguez N. Alba-Baena N.M. Rudolph J. Wellekoetter X.C. Li T.A. Osswald 《Journal of Manufacturing Processes》2012,14(3):388-392
For a successful enhancement of mechanical properties of metal matrix nanocomposites, a homogeneous nanoparticle dispersion and distribution in the solidified metal is required. Mechanical mixing can be used for initial break-up of agglomerates, and its study can be simplified with dimensional analysis. Using this technique, mixing time and vortex height were assessed while varying fluid properties, impeller angle, and angular speed. Three relevant dimensionless numbers were recognized: the Reynolds (Re), Froude and Galilei (Ga) numbers. Based on blade and impeller shaft angles, a modified Froude number (Fr*) was defined. These parameters were calculated experimentally, varying angular speed from 200 to 1000 rpm for three different impeller angles: 0°, 15° and 30°. This procedure was performed with three fluids: water, and two aqueous glycerin solutions (25% and 50% by volume). Digital images were taken and processed to measure vortex height. Mixing time was measured for water at 0° impeller angle, angular speed ranging from 200 to 1200 rpm. Results showed an optimal dimensionless mixing time with respect to Re. A linear relationship was found between dimensionless vortex height and Fr*. The first had a second order polynomial relationship with the product ReFr*, regardless of impeller angle. This relationship, together with the Ga, specific for each fluid, allows scaling the results to other fluids such as molten pure aluminum. This study allows experimenting in simpler systems that involve transparent fluids, room temperature and low cost, to then elaborate a prediction of vortex height in fluids where measurements are difficult and costly, such as molten metals. 相似文献
948.
Building regional priorities in forests for development and adaptation to climate change in the Congo Basin 总被引:1,自引:0,他引:1
Denis J. Sonwa Johnson N. Nkem Monica E. Idinoba Mekou Y. Bele Cyprain Jum 《Mitigation and Adaptation Strategies for Global Change》2012,17(4):441-450
Indentifying common priorities in shared natural resource systems constitutes an important platform for implementing adaptation
and a major step in sharing a common responsibility in addressing climate change. Predominated by discourses on REDD + (Reduced
Emissions from Deforestation and Forest Degradation and conservation, sustainable management of forests and enhancement of
forest carbon stocks in developing countries) with little emphasis on adaptation there is a risk of lack of policy measures
in addressing climate change in the Congo Basin. Forest products and ecosystem services provide security portfolios for the
predominantly rural communities, and play major roles in national development programmes in both revenue and employment opportunities.
Thus, raising the profile of forests in the policy arena especially in the twin roles of addressing climate change in mitigation
and adaptation and achieving resilient development is crucial. Within the framework of the Congo Basin Forests and Climate
Change Adaptation project (COFCCA) project, science policy dialogue was conducted to identify and prioritize forest based
sectors vulnerable to climate change but important to household livelihoods and national development. The goal of the prioritization
process was for the development of intervention in forest as measures for climate change adaptation in Central Africa. Participants
constituted a wide range of stakeholders (government, Non Governmental Organizations, research institutions, universities,
community leaders, private sectors etc.) as representatives from three countries directly involved in the project: Cameroon,
Central African Republic and Democratic Republic of Congo. Building on national priorities, four forest related sectors were
identified as common priorities at the regional level for focus on climate change adaptation. These sectors included: (1)
energy with emphasis on fuel wood and Charcoal; (2) Water principally quality, quantity, accessibility, etc.; (3) Food with emphasis on Non Timber Forest Products, and (4) Health linked to healthcare products (medicinal plants). Using these prioritized sectors, the project focused on addressing the impacts of climate change on local communities and the development of adaptation strategies in the three pilot countries
of the Congo Basin region. The four sectors constitute the key for development in the region and equally considered as priority sectors in the poverty
reduction papers. Focused research on these sectors can help to inject the role of forests in national and local development
and their potentials contributions to climate change adaptation in national and public discourses. Mainstreaming forest for
climate change adaptation into national development planning is the key to improve policy coherence and effectiveness in forest
management in the region. 相似文献
949.
J. S. Rice R. H. Moss P. J. Runci K. L. Anderson E. L. Malone 《Mitigation and Adaptation Strategies for Global Change》2012,17(7):805-819
A new modeling effort exploring the opportunities, constraints, and interactions between mitigation and adaptation at regional scale is utilizing stakeholder engagement in an innovative approach to guide model development and demonstration, including uncertainty characterization, to effectively inform regional decision making. This project, the integrated Regional Earth System Model (iRESM), employs structured stakeholder interactions and literature reviews to identify the most relevant adaptation and mitigation alternatives and decision criteria for each regional application of the framework. The information is used to identify important model capabilities and to provide a focus for numerical experiments. This paper presents the stakeholder research results from the first iRESM pilot region. The pilot region includes the Great Lakes Basin in the Midwest portion of the United States as well as other contiguous states. This geographic area (14 states in total) permits cohesive modeling of hydrologic systems while also providing strong gradients in climate, demography, land cover/land use, and energy supply and demand. The results from the stakeholder research indicate that, for this region, iRESM should prioritize addressing adaptation alternatives in the water resources, urban infrastructure, and agriculture sectors, including water conservation, expanded water quality monitoring, altered reservoir releases, lowered water intakes, urban infrastructure upgrades, increased electric power reserves in urban areas, and land use management/crop selection changes. For mitigation in this region, the stakeholder research implies that iRESM should focus on policies affecting the penetration of renewable energy technologies, and the costs and effectiveness of energy efficiency, bioenergy production, wind energy, and carbon capture and sequestration. 相似文献
950.
Stewart Jay Cohen Stephen Sheppard Alison Shaw David Flanders Sarah Burch Bill Taylor David Hutchinson Alex Cannon Stuart Hamilton Brent Burton Jeff Carmichael 《Mitigation and Adaptation Strategies for Global Change》2012,17(1):25-49
This paper provides an overview of a collaborative study on visualizing climate change at the local scale. A conceptual framework has been developed, in which local scenarios and visualizations of climate change impacts and response were created to facilitate local dialogue on incorporating climate change into long-term planning and implementation of community development decisions. As part of a larger effort to generate a new integrated participatory visioning process, this paper describes a case study of the District of North Vancouver which created visualizations of changing mountain snow and landscape conditions, and provides new insights on issues and dilemmas in using realistic landscape visualizations to depict scientific modelling projections, local responses to climate change, and uncertainty. Results from this study suggest that the visualizations, and subsequent dialogue sessions, did influence emotional response to climate change as well as self-assessed understanding of adaptation and mitigation response options. However, there is a need to test this visioning process with larger heterogeneous groups of participants in order to better assess its effectiveness in enabling dialogue on local responses to climate change. 相似文献