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161.
The acceptability of prenatal diagnosis for Down's syndrome has been extensively studied over the last 15 years but that of other pathologies remains largely unexplored. The main goals of this study were to approach physicians' opinions on six reasons for termination of pregnancy showing different deficiencies, i.e., Down's, Turner and Klinefelter syndromes, cystic fibrosis, spina bifida, and haemophilia, and to identify the origins of reserves. The influence of sociodemographic and professional characteristics of physicians on their opinions and attitudes during the consultation were studied. The data presented are based on information gathered in 1985 by a mailed questionnaire answered by 853 general practitioners, gynaecologists, obstetricians, and pediatricians in the Marseilles Genetic Centre's region. Stepwise logistic regression was used for the multivariate analysis. The results showed that 78 per cent of those answering favour termination of pregnancy for Down's syndrome and that only moral reticences were mentioned by the physicians opposed. Conversely, for haemophilia, only 21 per cent of the physicians considered this indication justified; those opposed were for the most part concerned that severity of illness did not justify termination of pregnancy. Overall, 33 per cent of physicians would voice their personal opinion on termination of pregnancy if so requested by consultees. Results on the influence of age and specialty evidenced their role on physicians' opinions. Indeed, 30 per cent of physicians opposed to pregnancy termination for one of the six fetal anomalies retained herein would modify their positions if diagnosis were possible in the first trimester of pregnancy. 相似文献
162.
In 1997, as part of a national program to determine and map critical loads, a lake survey was carried out in the Republic of Ireland. In total 200 lakes were sampled, which represents approximately 3.3% of the total lake population. The majority of lakes were situated in remote, high-altitude, acid-sensitive areas along the coastal margins of the country. Lake chemistry was dominated by marine inputs. Approximately 50% of the lakes had DOC > 5 mg L-1 due to the presence of organic soils in a large proportion of the catchments. Nonmarine sulfate concentrations were at background levels (< 20 mu eq L-1) in 50% of the lakes. Exceedance of critical load was observed in 7% of the sampled lakes (13 lakes). However, there are uncertainties in the critical load calculations due to the interference of sea salts and organic acids; accurate estimation under such conditions requires long-term lake and deposition chemistry. 相似文献
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Recent concerns surrounding the growth of mobility and associated increases in journey length and number of motorised journeys for an increasingly diverse pattern of trips have placed demands on the planning system in terms of the need to consider the land use-transport interaction. This paper first provides a review of relevant national planning policy in Scotland in particular. It then goes on to report findings from a recent survey which highlights the attitudes held by Scottish planning professionals to managing transport demand through land-use planning. The paper outlines the trade-offs encountered in practice between competing policy objectives. In Scotland there is no planning guidance equivalent to Planning Policy Guidance Note 13, which applies to England and Wales, around which there has been much debate on its impact on development control decisions and planning strategy. Draft guidance for Scotland was produced in 1996 for consultation and again in 1998, but at the time of writing has yet to be finalised. The findings from this study are timely in that they enable an assessment of the extent to which the planning system is being used to manage transport demand. Recent local government reorganisation in Scotland has resulted in significant changes to ways in which strategic planning and development control policy are likely to proceed. The paper focuses on the extent to which local authority policy emphasises the need to reduce travel through planning. 相似文献
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Spillover and crossover of sex‐based harassment from work to home: Supervisor gender harassment affects romantic relationship functioning via targets' anger
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Julian Barling 《组织行为杂志》2015,36(2):196-215
We investigate how gender harassment affects the romantic relationships (i.e., romantic relationship adjustment and romantic relationship efficacy) of female targets (spillover effects) and their romantic partners (crossover effects), and what role targets' anger in response to their gender harassment plays in these relationships. We explored these questions using two US samples. Sample 1 comprised 206 females, all of whom provided data on their gender harassment experiences, feelings of anger, and romantic relationship functioning. Sample 2 consisted of 60 romantic dyads. Females once again provided data on their gender harassment experiences and feelings of anger; their romantic partners reported on their own romantic relationship functioning. Full support emerged for hypothesized spillover effects: supervisor gender harassment indirectly and negatively influenced targets' romantic relationship adjustment and romantic relationship efficacy through target anger (Sample 1). Full support also emerged for hypothesized crossover effects: supervisor gender harassment indirectly and negatively influenced the romantic relationship adjustment and romantic relationship efficacy of targets' romantic partners through target anger (Sample 2). Implications for theory, research, and practice are considered. Copyright © 2014 John Wiley & Sons, Ltd. 相似文献
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Hampel M Mauffret A Pazdro K Blasco J 《Environmental monitoring and assessment》2012,184(10):6013-6023
Linear alkylbenzene sulfonate (LAS) is a group of anionic surfactants employed in the formulation of laundry and cleaning products, with a global production rate of 4 million metric tons. Sediments from the Polish coast of the southern Baltic Sea were collected at ten stations. Total LAS concentrations, measured by high-performance liquid chromatography, were between 0.04 and 0.72 mg LAS·kg(-1) dry weight. Highest LAS concentrations were found in suspended matter collected from the Vistula River, sediment collected close to the Vistula River mouth and from the Gdańsk Deep, known as the depositional area. With the obtained environmental LAS concentrations, a risk assessment for this surfactant has been carried out, based on publicly available acute and chronic toxicity data in target organisms. The results indicated that LAS could pose a low risk for the existing benthic community applying worst case scenario assessment. This is the first time that levels of LAS have been measured in environmental samples of the southern Baltic Sea. 相似文献
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Julian Adolphs Frank Kleinjung Jorge Numata Hans Mielke Klaus Abraham Helmut Schafft Christine Müller-Graf Matthias Greiner 《Chemosphere》2013
When food producing animals are contaminated with PCDD/F congeners, information on the contaminant’s concentration in the bodies of the animals at time of slaughter is needed for risk management purposes. We have developed a mathematical model for the kinetics of PCDD/Fs in growing pigs in case of contaminated feed fed for a limited duration of time. This model allows the prediction of concentrations in body fat. It considers absorption fractions of PCDD/Fs, clearance by metabolism, dilution by growth and excretion through fecal fat. The model parameters were calibrated by fitting the model to experimental data. On the basis of this toxicokinetic model a probabilistic model has been constructed. The probabilistic model handles the parameters with appropriate probability distributions and Monte-Carlo simulation technique, providing for realistic situations with many animals and a range of contaminations and feeding intervals. We applied the new model to describe the German dioxin incident of winter 2010/2011 and discuss its viability as decision tool. The approach demonstrated here is a showcase how a risk assessment in the case of contaminated feeding can be performed. 相似文献