Some observations of the structure of the choroid plexus and its cysts

The structure of the choroid plexus was studied in five normal human embryos, three normal fetuses and three fetuses with choroid plexus cysts. These were detected by ultrasound and the fetuses were karyotypically normal. The choroid plexus appears in the lateral cerebral ventricles at the seventh developmental week. The early structure is lobulated with vessels running in the mesenchymal stroma and forming capillary nets under the single-layered ependymal epithelium. This embryonal structure is converted into the fetal type during the ninth developmental week as the embryonal capillary net is replaced by elongated loops of wavy capillaries that lie under regular longitudinal epithelial folds. The choroid plexus cysts exhibited accumulation of fluid within distended mesenchymal stroma and did not show the wavy folds on this surface, which was smooth. Within this connective tissue of the cyst wall were distended angiomatous interconnecting thin-walled capillaries. Therefore, filled cavities were not lined by any epithelium. We suggest that fetal choroid plexuses cysts (at least in many cases) are in fact pseudocysts exhibiting angiomatous patterns of capillaries in their walls. Copyright © 2002 John Wiley & Sons, Ltd.     

Molecular taxonomy of vestimentiferans of the western Pacific and their phylogenetic relationship to species of the eastern Pacific

The nucleotide sequence of part (624 bp) of a mitochondrial gene for cytochrome oxidase I was determined for 46 escarpiid vestimentiferans collected from seven sites in the western Pacific and 49 individual specimens of Arcovestia ivanovi from two sites in the Manus Basin. Phylogenetic analysis, based on the newly obtained and previously reported sequences, indicated that escarpiids in the western Pacific can be divided into two tentative species, as we proposed in a previous report. While members of the first tentative species have been collected exclusively from a seep area at a depth of 300 m off the coast of central Japan, the members of the second species inhabit some sites at depths greater than 1,100 m, namely, seep areas in Japanese and Papua-New Guinean waters as well as hydrothermal vent fields in the Okinawa Trough and the Manus Basin. We detected no genetic structure among populations of the second tentative species. The first tentative species was more closely related to a species in the eastern Pacific, Escarpia spicata, and to a species in the Gulf of Mexico, Escarpia laminata, than to the second tentative species in the western Pacific. Sequences obtained from all arcovestiids were identical with the exception of those from three individuals, each of which included a single synonymous nucleotide substitution relative to the dominant haplotype, and no genetic differences were detected between specimens from the two sites in the Manus Basin.     

Prenatal diagnosis of a 45,X male with a SRY-bearing chromosome 21

Male phenotype associated with a 45,X karyotype is an infrequent finding. We present a case diagnosed prenatally on amniocentesis performed for maternal age. The male phenotype was associated with a translocation of a distal part of Yp including the pseudoautosomal SHOX gene and SRY gene on the short arm of a chromosome 21. By DNA analysis we could show that the X chromosome was of maternal origin and that the breakpoint was in interval 3 of the Y chromosome. Mechanisms and genetic counselling are discussed based on a review of published cases of 45,X and XX males. Copyright © 2002 John Wiley & Sons, Ltd.     

The role of new technologies in reducing energy demand

Energy efficiency is often stated to be the most cost-effective measure for satisfying our energy demand with minimal environmental damage. However, the potential energy savings attainable in 'the real world' are frequently overestimated, as is shown in an industrial case study of the glass industry. Nevertheless, there are significant energy savings to be realized, and the role of new technologies in this is important. However, the key to the effective use of new technology for improved energy efficiency is good management and. for best effect, it must be integrated into the normal resource management activities of a company.     

Taking Sustainable Cities Seriously: a comparative analysis of twenty-four US cities

After briefly reviewing some conceptual underpinnings of sustainable cities, this paper analyses and compares sustainable cities initiatives in 24 US cities. The central question addressed in the paper is why some cities seem to take sustainability more seriously than others. Numerous demographic, socioeconomic and other characteristics of the cities are correlated with an Index of Taking Sustainability Seriously, which is a composite of some 34 different variables indicating whether each city engages in specific sustainability programmes, policies or activities. Many of the standard explanations, such as the income and wealth of the community, the liberalness of the city and the growth pressures placed on the city, are found to exhibit no correlation with the seriousness of the sustainability effort. What do correlate with the Index are: reliance on manufacturing, where having more residents employed in manufacturing industries is associated with less seriousness; and, the age of the population, where cities with older populations take sustainability more seriously. This has three implications for the future development of sustainable cities. First, some of the cities that might be said to need sustainability programmes the most--cities with heavy manufacturing that are more prone to pollution production--are the least likely to take such programmes seriously. Secondly, as cities' manufacturing bases decline, they should find it increasingly feasible to engage in sustainability initiatives. And, thirdly, as the populations of cities age, policy-makers should also find it easier to support, develop and take seriously sustainability programmes.     

Progress in Restoration of the Mauritius Kestrel

In the 1970s, the Mauritius Kestrel ( Falco punctatus ) was the most endangered bird of prey in the world, at one time with only two known pairs surviving in the remnant native forest of the Black River Gorges (ca. 4,000 ha). At the end of the 1991–1992 breeding season, a minimum of 30 nesting pairs and more than 170 individuals were distributed in four separate forested areas, thanks mainly to manipulation of the reproductive potential of the wild pairs, to captive propagation, and to reintroduction (restocking). Since 1984, 139 young have been reared from 618 eggs laid by captive kestrels, and 147 from 265 wild eggs incubated and hatched in the laboratory; 235 young kestrels have been released on Mauritius by hacking and fostering. Adjustments in feeding and nesting habits of kestrels hacked and released outside the Black River Gorges in areas dominated by exotic vegetation and agriculture have allowed these kestrels to survive and reproduce in an array of previously unused habitats. Now that the kestrels have been released from dependence on the remnant and dying native forest, a viable population of more than 100 nesting pairs should be achievable in a few more years.