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121.
Dr Claire Julian-Reynier Genevieve Macquart-Moulin Jean-Paul Moatti Anderson Loundou Yvette Aurran Françoise Chabal Ségolene Aymé 《黑龙江环境通报》1993,13(7):613-627
The objective of this study was to explore women's attitudes towards prenatal diagnosis of trisomy 21 and to examine some of the factors possibly responsible for these attitudes before implementing in real practice serological screening of pregnant women at risk for trisomy 21. We carried out a telephone survey on a representative sample of women who had recently had a normal livebirth delivery in the Marseille district in 1990. The participation rate was 80 per cent and the average age of the mothers was 28-9 years. Among the 514 women interviewed, 78 per cent stated that they would ask for an amniocentesis for a 1 per cent risk of trisomy 21 at their next pregnancy. When adjusting for confounding factors, the decision to have or not to have an amniocentesis was found to depend not only on the women's attitude towards induced abortion, but also on their understanding of the risk involved and on the social context (knowing a handicapped child, discussion with the father). It also depended on the women's age and on what they knew about amniocentesis from the medical point of view. The risk of miscarriage can influence a woman's choice but this objection was not found to affect the women's decisions significantly in our survey. The data showed the existence of a high potential demand for fetal karyotyping. 相似文献
122.
Sylvie Gagnon William Fraser Dr Bertrand Fouquette Adrien Bastide Marc Bureau Jean-Yves Fontaine Céline Huot 《黑龙江环境通报》1992,12(1):9-18
During a 7-year period, 117 fetal karyotypes were available from 131 genetic amniocenteses. These procedures were performed between 14 and 37 weeks' gestation for the following abnormal ultrasound findings: (1) intrauterine growth retardation (IUGR)—61 cases; (2) fetal malformation—71 cases; and (3) amniotic fluid volume (AFV) abnormality—60 cases. Chromosomal abnormalities were identified in 19 cases (16.2 per cent). Aneuploidy was 2.5 times as frequent in the presence of malformations than in their absence. No correlation was demonstrated between specific fetal malformations and specific chromosomal abnormalities. Aneuploidy was also twice as frequent in the presence of symmetrical IUGR than in its absence. No chromosomal abnormalities were found among eight cases of asymmetrical IUGR. Four cases of aneuploidy presented with isolated IUGR, three of these involving the X chromosome. The frequency of aneuploidy was the same with or without abnormalities of AFV (14.3 versus 16.4 per cent). No chromosomal abnormality was found associated with isolated AFV abnormalities. 相似文献
123.
This study investigated the influence of cat urine odour in suppressing development and fertility in Campbell's hamster males.
Exposure to this odour from postnatal day 11 until day 45 (sexual maturation) resulted in reduced sex organ weights, reduced
testosterone levels and in an increase in abnormalities of the synaptonemal complex in both sex chromosomes and autosomes.
Subsequent breeding experiments revealed a significant decrease in litter size. All these data indicate a severe effect of
predator odour on the breeding success of potential prey species. It is assumed that these effects are caused by the sulphurous
compounds in the urine; however, the underlying mechanisms are not yet known.
Received: 31 January 2000 / Accepted in revised form: 6 June 2000 相似文献
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125.
D. P. N. Satchell 《Die Naturwissenschaften》1977,64(3):113-121
The classification and shorthand designation of chemical reactions are considered. It is concluded that single-step reactions can be divided into a finite number of types, each of which could be represented by an unambiguous symbol. The various types are listed and illustrated. Multi-step reactions, however, cannot be classified (in any detail) in a limited number of ways and for such reactions the use of symbols to represent each step unambiguously results in unwieldy designations. 相似文献
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