Information on tissue distribution of Dechlorane Plus (DP) and its dechlorinated analogs in wildlife is scarce. DP isomers and two dechlorinated compounds, anti-Cl11-DP and anti-Cl10-DP, were examined in the muscle, liver, and brain tissues of two bottom fish species collected from an electronic waste recycling site, South China. The median levels of syn-, anti-, and anti-Cl11-DP isomers in the tissues ranged 0.18-39.1, 0.22-52.9, and 0.01-5.63 ng/g wet wt, respectively. Anti-Cl10-DP was only detected in one muscle sample of mud carp (0.01 ng/g wet wt), although it was consistently detected in the sediments (0.42-0.83 ng/g dry wt). Preferential distribution in liver relative to muscle was observed for syn-DP and anti-Cl11-DP. However, a high persistent retention in the brain compared to the liver was observed for anti-DP, suggesting that this isomer can across the blood-brain barrier of fish, and may cause adverse effects to the nervous system in the exposed biota. 相似文献
Effluent organic matter from biological wastewater treatment plants is composed of degradation products and soluble microbial
products (SMP). Protein, polysaccharide, humic acid, and DNA were major biomolecules of SMP. Little is known about the effects
of SMP as microbially derived precursors on disinfection byproduct formation and speciation in biologically treated wastewater.
In addition, there has never been any attempt to directly chlorinate the major biomolecules of SMP. 相似文献
The adverse impacts of lead and cadmium exposure on health outcomes have been reported in the past. Few studies have been conducted on the relationship between lead and cadmium exposures and disability. We evaluated whether lead and cadmium exposures were associated with functional dependence including the total number of disabilities, activities of daily living (ADL), instrumental activities of daily living (IADL), leisure and social activities (LSA), lower extremity mobility (LEM), and general physical activities (GPA) in an elderly population. A total of 5513 eligible subjects were enrolled in the study from the National Health and Nutrition Examination Survey 2001–2006. Serum lead and cadmium exposure assessments were performed using atomic absorption spectrometry. Functional dependence was assessed by 19 structured questions. The relationships between lead and cadmium exposures and functional dependence were investigated using by multivariable linear regression models. Q2, Q3, and Q4 of lead exposure were significantly associated with the total number of disabilities, with β coefficients of ??0.62 (95% CI ??0.99, ??0.24), ??0.64 (95% CI ??1.02, ??0.26), and ??0.81 (95% CI ??1.19, ??0.42), respectively. This relationship remained significant in males. Furthermore, we analyzed the relationships between lead and cadmium exposure quartiles and various functional dependence metrics, and we determined that lead content was significantly associated with decreased ADL, LEM, and GPA (p?<?0.05) and cadmium content was inversely associated with ADL (p?<?0.05). Our study demonstrated a strong relationship between exposure to lead and cadmium and functional dependence in an elderly population.
Environmental Science and Pollution Research - In this study, the immature mice were taken to assess the potential neurological toxicity of lead (Pb) and di (n-butyl) phthalates (DBP) combination... 相似文献