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271.
Harriet von Koskull Ph.D. Annukka Ritvanen Pirkko Ämmälä Nina Gahmberg Riitta Salonen 《黑龙江环境通报》1989,9(6):433-437
Trisomy 12 mosaicism (44 per cent) was detected prenatally in cultured amniocytes. A cordocentesis was performed to confirm the result. Only normal cells were found in the fetal blood sample. The fetus was estimated to be at a low risk of having a chromosomal abnormality and the pregnancy continued. Eight days after birth, a congenital heart defect was detected in the child. Several dysmorphic features were also evident. Further karyotyping of different tissues revealed normal blood and urinary cells but trisomic cells in the placenta (100 per cent) and in skin fibroblasts (25 per cent). The child died at 5 weeks of age. In this case, the fetal blood sample failed to reveal the real chromosome constitution of the fetus. 相似文献
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利用景观信息分析和预测环境变化:扩展的基线观点—坦桑尼亚两?… 总被引:1,自引:0,他引:1
273.
Khanam Tahamina Rahman Abul Mola-Yudego Blas Pykäläinen Jouni 《Mitigation and Adaptation Strategies for Global Change》2020,25(4):733-734
Mitigation and Adaptation Strategies for Global Change - This paper was published on March 2017, Volume 22, Issue 3, 469–483pp, titled “Identification of structural breaks in the forest... 相似文献
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Gabriel L. Castiglioni Jorge Cuellar Raúl Rodrigo Jorge A. V. Costa Ranulfo Monte-Alegre 《Journal of Polymers and the Environment》2016,24(3):264-273
Macroporous poly(styrene-co-divinylbenzene) microparticles, with three different structural characteristics, have been synthesized and used as supports in the immobilization of lipase from Burkholderia cepacia. The best immobilization yield was found upon using microparticles with 35 % of divinylbenzene and the immobilized lipase on this type of particles was used as a catalyst to obtain biodiesel from soybean oil and ethanol. From the experimental results of the transesterification reaction, an empirical model quantitatively relating the temperature, the concentration of the enzyme and the transesterification yield was obtained. Statistical analysis of this model indicated that within the range of values of the variables studied (35–47 °C and 231–788 U/mg respectively) only the enzyme concentration exerted a significant influence on the reaction yield. Additionally, the good fit of a Michaelis–Menten-type model to the experimental results suggests that the limiting step of the reaction was the formation of the enzyme-substrate complex. 相似文献
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Carole Di Poi Lauris Evariste Alexis Séguin Antoine Mottier Julie Pedelucq Jean-Marc Lebel Antoine Serpentini Hélène Budzinski Katherine Costil 《Environmental science and pollution research international》2016,23(6):5002-5018
The bioconcentration potential of fluoxetine (FLX) and its biological effects were investigated in juvenile Pacific oyster exposed for 28 days to environmentally relevant concentrations of FLX (1 ng L?1, 100 ng L?1 and up to 10 μg L?1). FLX bioaccumulated in oyster flesh resulting in 28-day bioconcentration factors greater than 2,000 and 10,000 by referring to wet and dry weights, respectively. Nevertheless, FLX did not induce oyster mortality, delayed gametogenesis, or lead to adverse histopathological alterations. At the two highest concentrations, despite non-optimal trophic conditions, FLX stimulated shell growth but only in a transient manner, suggesting a role of serotonin in the regulation of feeding and metabolism in bivalves. Those high concentrations seemed to drive bell-shaped responses of catalase and glutathione S-transferase activities throughout the exposure period, which may indicate the activation of antioxidant enzyme synthesis and then an enhanced catabolic rate or direct inhibition of those enzymes. However, no clear oxidative stress was detected because no strong differences in thiobarbituric acid-reactive substance (TBARS) content (i.e. lipid peroxidation) were observed between oyster groups, suggesting that cellular defence mechanisms were effective. These results demonstrate the importance of considering additional biomarkers of oxidative stress to obtain a comprehensive overview of the FLX-induced changes in marine bivalves exposed under realistic conditions. Considering the battery of biomarkers used, FLX appears to induce little or no effects on oyster physiology even at a concentration of 10 μg L?1. These results do not confirm the lowest observed effect concentration (LOEC) values reported by some authors in other mollusc species. 相似文献