Targeting natural products against SARS-CoV-2

Environmental Science and Pollution Research - The human coronavirus disease (COVID-19) pandemic is caused by a novel coronavirus; the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2)....     

Optimum techno-eco performance requisites for vacuum annulus tube collector–assisted double-slope solar desaltification unit integrated modified parabolic concentrator

Environmental Science and Pollution Research - This work presents a novel approach for a double-slope solar desaltification system having parallel array of evacuated annular tube collectors with...     

A composite polyphenol-rich extract improved growth performance,ruminal fermentation and immunity,while decreasing methanogenesis and excretion of nitrogen and phosphorus in growing buffaloes

Environmental Science and Pollution Research - The effects of a composite polyphenolic-rich extract (CPRE) on ruminal fermentation, nutrient utilisation, growth performance, excretion of nitrogen...     

Anticipated pharmacological role of Aviptadil on COVID-19

Environmental Science and Pollution Research - Vasoactive intestinal peptide (VIP) is a neuropeptide that is produced by the lymphoid cells and plays a major role in immunological functions for...     

Exploration of potential role of Rho GTPase in nicotine dependence-induced withdrawal syndrome in mice

Environmental Science and Pollution Research - The RhoA gene showed an important genotypic association with nicotine dependence and smoking initiation. The current study aims to investigate the...     

Pharmacological evaluation of Thuja occidentalis for the attenuation of neuropathy via AGEs and TNF-α inhibition in diabetic neuropathic rats

Environmental Science and Pollution Research - When diabetes neuropathy occurs, the oxidative stress caused by chronic hyperglycemia may result in chronic neuronal damage. To mitigate the effects...     

Predicting the distributional range shifts of Rhizocarpon geographicum (L.) DC. in Indian Himalayan Region under future climate scenarios

Environmental Science and Pollution Research - Himalaya, the highest mountain system in the world and house of important biodiversity hotspot, is sensitive to projected warming by climate change....     

ESTIMATING PARAMETERS OF EV1 DISTRIBUTION FOR FLOOD FREQUENCY ANALYSIS1

ABSTRACT: The parameters of the extreme value type 1 distribution were estimated for 55 annual flood data sets by seven methods. These are the methods of (1) moments, (2) probability weighted moments, (3) mixed moments, (4) maximum likelihood estimation, (5) incomplete means, (6) principle of maximum entropy, and (7) least squares. The method of maximum likelihood estimation was found to be the best and the method of incomplete means the worst. The differences between the methods of principle of maximum entropy, probability weighted moments, moments, and least squares were only minor. The difference between these methods and the method of maximum likelihood was not pronounced.     

Phytoremediation of radiostrontium ((90)Sr) and radiocesium ((137)Cs) using giant milky weed (Calotropis gigantea R.Br.) plants

Potential of plants to remove radionuclides/toxic elements from soils and solutions can be successfully applied for removal of important radionuclides such as strontium-90 (⁹⁰Sr) and cesium-137 (¹³⁷Cs). When uptake of ¹³⁷Cs and ⁹⁰Sr by Calotropis gigantea plants incubated in distilled water spiked with the radionuclides either alone or in combination was studied, it was found to have a high efficiency for the removal of ⁹⁰Sr, with 90% being removed from solutions (5 × 10³ kBq l⁻¹) within 24 h of incubation. However, in case of ¹³⁷Cs, about 44% could be removed from solutions (5 × 10³ kBq l⁻¹) at the end of 168 h of incubation. Accumulation of ⁹⁰Sr and ¹³⁷Cs was higher in roots compared to shoots. The plants could remediate both ⁹⁰Sr and ¹³⁷Cs when they were added together to the solution. When two months old plants were incubated in low level nuclear waste, 99% of activity disappeared at the end of 15 days. The present study suggests that C. gigantea could be used as a potential candidate plant for phytoremediation of ⁹⁰Sr and ¹³⁷Cs.     

Impact of endosulfan on the profiles of phospholipids at sublethal concentration in the male Heteropneustes fossilis (Bloch)

Male Heteropneustes fossilis were exposed for 30 days at sublethal concentration (0.002 ppm) during different phases of its annual reproductive cycle. Its impact on total phospholipids (TP), phosphatidylcholine (PC), phosphatidylserine (PS), phosphatdylinositol (PI) and phosphatidylethanolamine (PE) were measured in liver, plasma and testes. During preparatory phase, in general, the levels for TP, PC, PS, PI and PE decreased after endosulfan exposure in the above tissues. During prespawning and spawning phases, the phospholipids also showed decreasing trend. The postspawning phase, exhibited decline in hepatic levels of PS and PI only and remained unaffected in the other two tissues. During the resting phase too, the hepatic levels of TP, PS and PI declined and remained unaltered in others. The present results indicate that endosulfan have very selective effects on phospholipids classes during different phases of the annual reproductive cycle interfering with the production of lipid deprived energy i.e. vitellogenin. In general, endosulfan has inhibitory role during reproductive growth affecting phospholipid biosynthesis via hepatic enzyme systems as well as by hormonal imbalance.