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271.
Helen Carnaghan Catherine P. James Paul B. Charlesworth Marco Ghionzoli Susana Pereira Mohamed Elkhouli David Baud Paolo De Coppi Greg Ryan Prakesh S. Shah Mark Davenport Anna L. David Agostino Pierro Simon Eaton Gastroschisis Study Group 《黑龙江环境通报》2020,40(8):991-997
Objective
In gastroschisis, there is evidence to suggest that gut dysfunction develops secondary to bowel inflammation; we aimed to evaluate the effect of maternal antenatal corticosteroids administered for obstetric reasons on time to full enteral feeds in a multicenter cohort study of gastroschisis infants.Methods
A three center, retrospective cohort study (1992-2013) with linked fetal/neonatal gastroschisis data was conducted. The primary outcome measure was time to full enteral feeds (a surrogate measure for bowel function) and secondary outcome measure was length of hospital stay. Analysis included Mann-Whitney and Cox regression.Results
Of 500 patients included in the study, 69 (GA at birth 34 [25-38] weeks) received antenatal corticosteroids and 431 (GA at birth 37 [31-41] weeks) did not. Antenatal corticosteroids had no effect on the rate of reaching full feeds (Hazard ratio HR 1.0 [95% CI: 0.8-1.4]). However, complex gastroschisis (HR 0.3 [95% CI: 0.2-0.4]) was associated with an increased time to reach full feeds and later GA at birth (HR 1.1 per week increase in GA [95% CI: 1.1-1.2]) was associated with a decreased time to reach full feeds.Conclusion
Maternal antenatal corticosteroids use, under current antenatal steroid protocols, in gastroschisis is not associated with an improvement in neonatal outcomes such as time to full enteral feeds or length of hospital stay. 相似文献272.
Bertanne Visser Cécile Le Lann Helen Snaas Ian C. W. Hardy Jeffrey A. Harvey 《Behavioral ecology and sociobiology》2014,68(1):105-113
Population-wide mating patterns can select for equal parental investment in both sexes, but limiting resources, such as mates or developmental substrates, can increase competition leading to biased sex ratios in favor of either sex. Such competition for resources typically occurs in spatially structured populations, where dispersal is limited. In this laboratory study, we investigate if and how resource competition affects sex allocation, discriminative behaviors and competitive interactions of the wingless hyperparasitoid Gelis acororum, which exploits patchily distributed hosts. We show that G. acororum sex ratios are male-biased and that this is not a consequence of constrained reproduction by virgin females. Our results suggest that this pattern of reproductive investment, which is only rarely observed in parasitoids, is a consequence of resource limitation, in terms of hosts rather than mates. Further, G. acororum appears not to respond to intrinsic host quality or to prior oviposition in its host. When competing inter-specifically for host resources, G. acororum outcompetes its congener Gelis agilis, but does so mainly when ovipositing on the host first. Overall, our results suggest that host resource limitation could be an important environmental factor shaping sex allocation in G. acororum, with competition taking place both intra- and inter-specifically. 相似文献
273.
A study of a small sample of construction fatal accidents was used to pilot a potential method of analysis for the UK Health and Safety Executive (HSE) Construction Division. The work was conducted in the context of a Governmental Inquiry into construction fatalities in 2009, but has been developed further since. The sample of 26 accidents (28 fatalities) was drawn from the 211 fatal accidents in the years ending 2006–2008, to be broadly illustrative of the range of accident characteristics. The accidents were analysed on the basis of available inspectorate reports and structured interviews with the investigating inspectors. A standard method of classification on four levels was developed, based on the Human Factors Analysis and Classification System (HFACS) classification of errors and task level factors, with additional categories covering the organisational and regulatory/market levels of the system. The results showed a concentration of underlying factors associated with inadequacies in planning and risk assessment, competence assurance, hardware design, purchase and installation, and contracting strategy. These findings were partially validated by comparing them with another sample of 50 accidents analysed earlier by the HSE. This paper describes the development and testing of the investigation and classification method and how it is being further developed since the initial study. It also provides a summary of the findings relating to underlying causes. 相似文献
274.
275.
The global ocean and atmosphere are warming. There is increasing evidence suggesting that, in addition to other environmental factors, climate change is affecting species distributions and local population dynamics. Additionally, as a consequence of the growing levels of atmospheric carbon dioxide (CO2), the oceans are taking up increasing amounts of this CO2, causing ocean pH to decrease (ocean acidification). The relative impacts of ocean acidification on population dynamics have yet to be investigated, despite many studies indicating that there will be at least a sublethal impact on many marine organisms, particularly key calcifying organisms. Using empirical data, we forced a barnacle (Semibalanus balanoides) population model to investigate the relative influence of sea surface temperature (SST) and ocean acidification on a population nearing the southern limit of its geographic distribution. Hindcast models were compared to observational data from Cellar Beach (southwestern United Kingdom). Results indicate that a declining pH trend (-0.0017 unit/yr), indicative of ocean acidification over the past 50 years, does not cause an observable impact on the population abundance relative to changes caused by fluctuations in temperature. Below the critical temperature (here T(crit) = 13.1 degrees C), pH has a more significant affect on population dynamics at this southern range edge. However, above this value, SST has the overriding influence. At lower SST, a decrease in pH (according to the National Bureau of Standards, pHNBs) from 8.2 to 7.8 can significantly decrease the population abundance. The lethal impacts of ocean acidification observed in experiments on early life stages reduce cumulative survival by approximately 25%, which again will significantly alter the population level at this southern limit. Furthermore, forecast predictions from this model suggest that combined acidification and warming cause this local population to die out 10 years earlier than would occur if there was only global warming and no concomitant decrease in pH. 相似文献
276.
Hooper HL Connon R Callaghan A Fryer G Yarwood-Buchanan S Biggs J Maund SJ Hutchinson TH Sibly RM 《Ecology》2008,89(4):1015-1022
The concept of an organism's niche is central to ecological theory, but an operational definition is needed that allows both its experimental delineation and interpretation of field distributions of the species. Here we use population growth rate (hereafter, pgr) to define the niche as the set of points in niche space where pgr > 0. If there are just two axes to the niche space, their relationship to pgr can be pictured as a contour map in which pgr varies along the axes in the same way that the height of land above sea level varies with latitude and longitude. In laboratory experiments we measured the pgr of Daphnia magna over a grid of values of pH and Ca2+, and so defined its "laboratory niche" in pH-Ca2+ space. The position of the laboratory niche boundary suggests that population persistence is only possible above 0.5 mg Ca2+/L and between pH 5.75 and pH 9, though more Ca2+ is needed at lower pH values. To see how well the measured niche predicts the field distribution of D. magna, we examined relevant field data from 422 sites in England and Wales. Of the 58 colonized water bodies, 56 lay within the laboratory niche. Very few of the sites near the niche boundary were colonized, probably because pgr there is so low that populations are vulnerable to extinction by other factors. Our study shows how the niche can be quantified and used to predict field distributions successfully. 相似文献
277.
The study of ecological differences among coexisting microparasites has been largely neglected, but it addresses important and unusual issues because there is no clear distinction in such cases between conventional (resource) and apparent competition. Here patterns in the population dynamics are examined for four species of Bartonella (bacterial parasites) coexisting in two wild rodent hosts, bank voles (Clethrionomys glareolus) and wood mice (Apodemus sylvaticus). Using generalized linear modeling and mixed effects models, we examine, for these four species, seasonal patterns and dependencies on host density (both direct and delayed) and, having accounted for these, any differences in prevalence between the two hosts. Whereas previous studies had failed to uncover species differences, here all four were different. Two, B. doshiae and B. taylorii, were more prevalent in wood mice, and one, B. birtlesii, was more prevalent in bank voles. B. birtlesii, B. grahamii, and B. taylorii peaked in prevalence in the fall, whereas B. doshiae peaked in spring. For B. birtlesii in bank voles, density dependence was direct, but for B. taylorii in wood mice density dependence was delayed. B. birtlesii prevalence in wood mice was related to bank vole density. The implications of these differences for species coexistence are discussed. 相似文献
278.
279.
Paul S. PhillipsTerry Tudor Helen BirdMargaret Bates 《Resources, Conservation and Recycling》2011,55(3):335-343
In 2007, in England, the Department of Environment, Food and Rural Affairs (Defra) published Waste Strategy 2007 for England. To help drive the required behaviour change for increased sustainable practice the Government in England signalled up in the Strategy the intention to launch a Zero Waste Places (ZWP) initiative to develop innovative and exemplary practice. By inviting places (including cities, towns and rural communities) to bid for ZWP status, the successful applicants were then expected to become exemplars of good environmental practice on all waste issues. The ZWP programme commenced in October 2008 with the selection of 6 distinct places based upon an application by a partnership containing a Local Authority or in one case a Regional Development Agency. The places ranged in size from the very small (one street of 201 properties) to a Region of England (5 million population). These 6 were chosen from an initial list of 12 applicants via a rigorous selection process against fixed criteria that were designed to support Zero Waste practice. The funding was £70,258 and the mean was £11,709. The overall assessment suggests that the Local Authorities and their project partners rose to the challenge of zero waste and in most cases met or even exceeded their objectives (meeting at least 80% of aims and planned actions) and achieved high value for money in terms of Government funded initiatives. Evaluation suggested that there is a requirement to link, in the future, ZWP initiatives with other recent developments such as Transition Towns, Eco-Town and Total Place developments within Local Authorities. A Certificated Standard for ZWP was developed and is perceived as being both useful and valuable and it is hoped that it will spur a large number of new ZWP applications. 相似文献
280.
Historical records of sand drift and dune-building along the coastline of Western Europe provide insights into the natural
processes of sand dune accretion and both the impacts of, and human responses to, sand incursions. The analysis of documentary
records, instrumental data and proxy records over the last 1,000 years indicates that this period, which included the Little
Ice Age (AD 1570–1900), featured numerous episodes of sand drift and dune development driven by strong winds associated with
Atlantic storms. It is estimated that sand drift affected over a quarter of a million hectares of coastal land in Western
Europe. The widespread use of vegetation to stabilise coastal dune systems and prevent sand drift is documented across Europe
from AD 1100 and by the start of the 20th century all of the larger coastal dune systems in Portugal, France, Britain and
Denmark were comparatively inactive. Given that Atlantic storminess has remained more or less unchanged over the last 200 years,
modern dune management strategies which consider dune devegetation, driven by an increasing focus on ‘naturalness’, may give
rise to a recurrence of sand drift problems. Predictions of increased storm frequencies by the end of the 21st century, coupled
with sea level rise and potential changes in sand supply will present further challenges for the more ‘dynamic’ dune management
strategies. 相似文献