太湖典型河网区地表水与沉积物氮、磷和重金属含量空间分异

将无锡城乡交错区河网分为城镇生活区水巷、工业区主河道、农业区主河道、农业区支流和鱼塘5种类型区.通过秋季(旱季)和夏季(雨季)2次采样,研究氮、磷和Cu、Zn、Pb、Cr、Cd在地表水和沉积物中的含量及其空间变化.结果表明:(1)城乡交错区地表水氮、磷来源于生活污染和工业污染的比例大于农田,同时具有来源分散、污染面广的特征.(2)由于城镇地表径流和工业活动影响,各类型区地表水重金属含量均有不同程度提高.但地表水重金属主要沿主河道迁移,旱季和雨季主河道重金属含量均大于农业区支流,而且随着与城镇距离增加,主河道沉积物重金属含量迅速降低,重金属污染影响范围较小.(3)与重金属相比,地表水氮、磷污染仍是太湖水网区主要的环境问题.但城镇及其周围河流沉积物中富集的重金属含量很高,其潜在环境风险不容忽视.     

Effect of Classification Procedure on the Performance of Numerically Defined Ecological Regions

Ecological regionalizations define geographic regions exhibiting relative homogeneity in ecological (i.e., environmental and biotic) characteristics. Multivariate clustering methods have been used to define ecological regions based on subjectively chosen environmental variables. We developed and tested three procedures for defining ecological regions based on spatial modeling of a multivariate target pattern that is represented by compositional dissimilarities between locations (e.g., taxonomic dissimilarities). The procedures use a “training dataset” representing the target pattern and models this as a function of environmental variables. The model is then extrapolated to the entire domain of interest. Environmental data for our analysis were drawn from a 400 m grid covering all of Switzerland and consisted of 12 variables describing climate, topography and lithology. Our target patterns comprised land cover composition of each grid cell that was derived from interpretation of aerial photographs. For Regionalization 1 we used conventional cluster analysis of the environmental variables to define 60 hierarchically organized levels comprising from 5 to 300 regions. Regionalization 1 provided a base-case for comparison with the model-based regionalizations. Regionalization 2, 3 and 4 also comprised 60 hierarchically organized levels and were derived by modeling land cover composition for 4000 randomly selected “training” cells. Regionalization 2 was based on cluster analysis of environmental variables that were transformed based on a Generalized Dissimilarity Model (GDM). Regionalization 3 and 4 were defined by clustering the training cells based on their land cover composition followed by predictive modeling of the distribution of the land cover clusters using Classification and Regression Tree (CART) and Random Forest (RF) models. Independent test data (i.e. not used to train the models) were used to test the discrimination of land cover composition at all hierarchical levels of the regionalizations using the classification strength (CS) statistic. CS for all the model-based regionalizations was significantly higher than for Regionalization 1. Regionalization 3 and 4 performed significantly better than Regionalization 2 at finer hierarchical levels (many regions) and Regionalization 4 performed significantly better than Regionalization 3 for coarse levels of detail (few regions). Compositional modeling can significantly increase the performance of numerically defined ecological regionalizations. CART and RF-based models appear to produce stronger regionalizations because discriminating variables are able to change at each hierarchic level.     

Rapid whole exome sequencing in pregnancies to identify the underlying genetic cause in fetuses with congenital anomalies detected by ultrasound imaging

Objective

The purpose of this study was to explore the diagnostic yield and clinical utility of trio-based rapid whole exome sequencing (rWES) in pregnancies of fetuses with a wide range of congenital anomalies detected by ultrasound imaging.

Methods

In this observational study, we analyzed the first 54 cases referred to our laboratory for prenatal rWES to support clinical decision making, after the sonographic detection of fetal congenital anomalies. The most common identified congenital anomalies were skeletal dysplasia (n = 20), multiple major fetal congenital anomalies (n = 17) and intracerebral structural anomalies (n = 7).

Results

A conclusive diagnosis was identified in 18 of the 54 cases (33%). Pathogenic variants were detected most often in fetuses with skeletal dysplasia (n = 11) followed by fetuses with multiple major fetal congenital anomalies (n = 4) and intracerebral structural anomalies (n = 3). A survey, completed by the physicians for 37 of 54 cases, indicated that the rWES results impacted clinical decision making in 68% of cases.

Conclusions

These results suggest that rWES improves prenatal diagnosis of fetuses with congenital anomalies, and has an important impact on prenatal and peripartum parental and clinical decision making.     

An Alternative Approach to Photochemical Ozone Creation Potentials Applied under European Conditions

ABSTRACT

Photochemical ozone creation potential (POCP) values for 83 different volatile organic compounds (VOCs), including CO and CH₄, were calculated under different environmental conditions representative for Europe. These calculations show that variations in POCP values are large between different types of chemical environments and that POCP values for VOCs should be presented as ranges instead of single values. POCP ranges are based on the extremes of the POCP values and are defined with the intention to include all POCP values an individual VOC will obtain in any European environment where O₃ formation is of environmental concern. The POCP ranges indicate large differences in O₃ production between individual VOCs, which justifies the use of this ranking scale instead of treating all VOCs as a homogeneous group of species in abatement strategies.

Both the average O₃ production over 96 hr and the maximum contribution to the O₃ concentration were studied. The most efficient O₃ producers were found to be iso-prene, 2-methyl-2-butene, and acrolein. As a group, the alkenes are the most potent O₃ producers, followed by higher alkanes and then the aromatics. The calculated values show a good agreement with previously calculated POCP values under northern European conditions.     

南非志愿举措的发展

采取少数几个小的志愿步骤 南非的志愿举措大部分是由于公司经营所在的不确定法规环境的结果.环境立法的确存在,但过去执法不力,这部分地由于工业界和政府都认为增长和就业机会是与环境管理相冲突的,而且前者优于后者.希望随着可持续发展的信息得到更好的理解,那些冲突类别将成为过去的事情.     

Science-practice interactions linked to climate adaptation in two contexts: municipal planning and forestry in Sweden

This paper examines the science-practice interface in the process of adapting to climate change in society. This paper analyses science-based stakeholder dialogues with climate scientists, municipal officers and private individual forest owners in Sweden, and examines how local experts both share scientific knowledge and experience and integrate it into their work strategies and practices. The results demonstrate how local experts jointly conceptualise climate adaptation, how scientific knowledge is domesticated among local experts in dialogue with scientific experts, the emergence of anchoring devices, and the boundary-spanning functions that are at work in the respective sectors.