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排序方式: 共有201条查询结果,搜索用时 46 毫秒
1.
2.
Vanessa M. Barnabei MD PhD David A. Krantz James N. Macri John W. Larsen Jr 《黑龙江环境通报》1995,15(12):1131-1134
We have applied our multimarker approach of maternal serum alpha-fetoprotein (AFP) and free-beta human chorionic gonadotropin (hCG) for Down syndrome screening to multiple gestations to assess its efficacy for improved detection of twin and triplet pregnancies. This study matched 225 cases of twin pregnancy and 39 cases of triplet pregnancy each with ten singleton pregnancies based on gestational week, race, time to receive sample, time of year of sample, and geographical area. The ratios of the MOM for each group at the tenth, 50th, and 90th percentiles were compared by the Wilcoxon test. Risks for twins were calculated using Bayes' rule, the age-related incidence of twins, and the levels of AFP and free-beta hCG. The tenth, 50th, and 90th percentiles of free-beta hCG MOMs in twin and triplet cases were 0.85, 1.99, and 4.51, and 1.38, 2.78, and 4.07, respectively. For AFP, the MOMs at these percentiles were 1.26, 1.91, and 2.99, and 2.02, 2.68, and 5.30, respectively. The twin and triplet distributions for each marker were statistically significantly different from the singleton distributions (P<0.0001) and from each other (P=0.0012). At a twin risk cut-off of 1 in 50, 77.4 per cent of all twin gestations can be detected in a second-trimester AFP and free-beta hCG screening protocol with 5.1 per cent of singleton pregnancies falsely identified as at risk for twins. Our dual marker protocol for mid-trimester pregnancy screening combining AFP and free-beta hCG can identify over 77 per cent of twin pregnancies in women less than 35 years of age. This benefit may contribute to an improved outcome of pregnancy by early detection of multiple gestation. 相似文献
3.
Natural biodegradation can contain groundwaters impacted by creosote and pentachlorophenol. Using natural biodegradation for such sites is attractive because groundwater restoration is often impracticable, but the dissolved plumes are biodegradable and exert relatively low oxygen demands. Three case studies of its successful use are presented, with emphasis on the types of evidence needed, the rates and extents of removal, and the strategies for incorporating natural biodegradation into a remediation approach. Natural biodegradation was proven at all three sites, using a combination of field geochemical measurements, laboratory simulations, and computer modeling. Contaminant plumes at these three sites were contained within 100 to 700 feet downgradient of the apparent sources, although the rates of biodegradation varied widely. Natural biodegradation should be considered as part of an overall remedial strategy for most sites contaminated by creosote and/or pentachlorophenol. 相似文献
4.
Larisse Montero Matthew Duane Urbano Manfredi Covadonga Astorga Giorgio Martini Massimo Carriero Alois Krasenbrink B.R. Larsen 《Atmospheric environment (Oxford, England : 1994)》2010,44(18):2167-2175
The present paper presents results from the analysis of 29 individual C2–C9 hydrocarbons (HCs) specified in the European Commission Ozone Directive. The 29 HCs are measured in exhaust from common, contemporary vehicle/engine/fuel technologies for which very little or no data is available in the literature. The obtained HC emission fingerprints are compared with fingerprints deriving from technologies that are being phased out in Europe. Based on the total of 138 emission tests, thirteen type-specific fingerprints are extracted (Mean ± SD percentage contributions from individual HCs to the total mass of the 29 HCs), essential for receptor modelling source apportionment. The different types represent exhaust from Euro3 and Euro4 light-duty (LD) diesel and petrol-vehicles, Euro3 heavy-duty (HD) diesel exhaust, and exhaust from 2-stroke preEuro, Euro1 and Euro2 mopeds. The fuels comprise liquefied petroleum gas, petrol/ethanol blends (0–85% ethanol), and mineral diesel in various blends (0–100%) with fatty acid methyl esters, rapeseed methyl esters palm oil methyl esters, soybean oil methyl or sunflower oil methyl esters. Type-specific tracer compounds (markers) are identified for the various vehicle/engine/fuel technologies.An important finding is an insignificant effect on the HC fingerprints of varying the test driving cycle, indicating that combining HC fingerprints from different emission studies for receptor modelling purposes would be a robust approach.The obtained results are discussed in the context of atmospheric ozone formation and health implications from emissions (mg km?1 for LD and mopeds and mg kW h?1 for HD, all normalised to fuel consumption: mg dm?3 fuel) of the harmful HCs, benzene and 1,3-butadiene.Another important finding is a strong linear correlation of the regulated “total” hydrocarbon emissions (tot-HC) with the ozone formation potential of the 29 HCs (ΣPO3 = (1.66 ± 0.04) × tot-RH; r2 = 0.93). Tot-HC is routinely monitored in emission control laboratories, whereas C2–C9 are not. The revealed strong correlations broadens the usability of data from vehicle emission control laboratories and facilitates the comparison of the ozone formation potential of HCs in exhaust from of old and new vehicle/engine/fuel technologies. 相似文献
5.
Day-of-week patterns of particulate matter and its chemical components at selected sites in California 总被引:2,自引:0,他引:2
Motallebi N Tran H Croes BE Larsen LC 《Journal of the Air & Waste Management Association (1995)》2003,53(7):876-888
This paper analyzes day-of-week variations in concentrations of particulate matter (PM) in California. Because volatile organic compounds (VOCs) and oxides of nitrogen (NOx) are not only precursors of ozone (O3) but also of secondary PM, it is useful to know whether the variations by day of week in these precursors are also evident in PM data. Concentrations of PM < or = 10 microm (PM10) and < or = 2.5 microm in aerodynamic diameter (PM2.5) were analyzed. PM concentrations exhibit a general weekly pattern, with the maximum occurring late in the workweek and the minimum occurring on weekends (especially Sunday); however, this pattern does not prevail at all sites and areas. PM nitrate (NO3-) data from Size Selective Inlet (SSI) samplers in the South Coast Air Basin (SoCAB) tend to be somewhat lower on weekends compared with weekdays. During 1988-1991, the weekend average was lower than the weekday average at 8 of 13 locations, with an average decrease of 1%. During 1997-2000, the weekend average was lower than the weekday average at 10 of 13 locations, with an average decrease of 6%. The weekend averages are generally lower than weekday averages for sulfates, organic carbon, and elemental carbon. Because heavy-duty trucks typically represent a major source of elemental carbon, the weekend decrease in heavy-duty truck traffic may also result in a decrease in ambient elemental carbon concentrations. 相似文献
6.
Biosensors for detection of mercury in contaminated soils 总被引:1,自引:0,他引:1
Bontidean I Mortari A Leth S Brown NL Karlson U Larsen MM Vangronsveld J Corbisier P Csöregi E 《Environmental pollution (Barking, Essex : 1987)》2004,131(2):255-262
Biosensors based on whole bacterial cells and on bacterial heavy metal binding protein were used to determine the mercury concentration in soil. The soil samples were collected in a vegetable garden accidentally contaminated with elemental mercury 25 years earlier. Bioavailable mercury was measured using different sensors: a protein-based biosensor, a whole bacterial cell based biosensor, and a plant sensor, i.e. morphological and biochemical responses in primary leaves and roots of bean seedlings grown in the mercury-contaminated soil. For comparison the total mercury concentration of the soil samples was determined by AAS. Whole bacterial cell and protein-based biosensors gave accurate responses proportional to the total amount of mercury in the soil samples. On the contrary, plant sensors were found to be less useful indicators of soil mercury contamination, as determined by plant biomass, mercury content of primary leaves and enzyme activities. 相似文献
7.
River channel migration and cutoff events within large river riparian corridors create heterogeneous and biologically diverse
landscapes. However, channel stabilization (riprap and levees) impede the formation and maintenance of riparian areas. These
impacts can be mitigated by setting channel constraints away from the channel. Using a meander migration model to measure
land affected, we examined the relationship between setback distance and riparian and off-channel aquatic habitat formation
on a 28-km reach of the Sacramento River, California, USA. We simulated 100 years of channel migration and cutoff events
using 11 setback scenarios: 1 with existing riprap and 10 assuming setback constraints from about 0.5 to 4 bankfull channel
widths (bankfull width: 235 m) from the channel. The percentage of land reworked by the river in 100 years relative to current
(riprap) conditions ranged from 172% for the 100-m constraint setback scenario to 790% for the 800-m scenario. Three basic
patterns occur as the setback distance increases due to different migration and cutoff dynamics: complete restriction of cutoffs,
partial restriction of cutoffs, and no restriction of cutoffs. Complete cutoff restriction occurred at distances less than
about one bankfull channel width (235 m), and no cutoff restriction occurred at distances greater than about three bankfull
widths (∼700 m). Managing for point bars alone allows the setbacks to be narrower than managing for cutoffs and aquatic habitat.
Results suggest that site-specific “restriction of cutoff” thresholds can be identified to optimize habitat benefits versus
cost of acquired land along rivers affected by migration processes. 相似文献
8.
Supporting Diverse Data Providers in the Open Water Data Initiative: Communicating Water Data Quality and Fitness of Use
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Sara Larsen Stuart Hamilton Jessica Lucido Bradley Garner Dwane Young 《Journal of the American Water Resources Association》2016,52(4):859-872
Shared, trusted, timely data are essential elements for the cooperation needed to optimize economic, ecologic, and public safety concerns related to water. The Open Water Data Initiative (OWDI) will provide a fully scalable platform that can support a wide variety of data from many diverse providers. Many of these will be larger, well‐established, and trusted agencies with a history of providing well‐documented, standardized, and archive‐ready products. However, some potential partners may be smaller, distributed, and relatively unknown or untested as data providers. The data these partners will provide are valuable and can be used to fill in many data gaps, but can also be variable in quality or supplied in nonstandardized formats. They may also reflect the smaller partners' variable budgets and missions, be intermittent, or of unknown provenance. A challenge for the OWDI will be to convey the quality and the contextual “fitness” of data from providers other than the most trusted brands. This article reviews past and current methods for documenting data quality. Three case studies are provided that describe processes and pathways for effective data‐sharing and publication initiatives. They also illustrate how partners may work together to find a metadata reporting threshold that encourages participation while maintaining high data integrity. And lastly, potential governance is proposed that may assist smaller partners with short‐ and long‐term participation in the OWDI. 相似文献
9.
Lawrence C. Larsen Mena Shah 《Journal of the Air & Waste Management Association (1995)》2016,66(1):38-52
Although networks of environmental monitors are constantly improving through advances in technology and management, instances of missing data still occur. Many methods of imputing values for missing data are available, but they are often difficult to use or produce unsatisfactory results. I-Bot (short for “Imputation Robot”) is a context-intensive approach to the imputation of missing data in data sets from networks of environmental monitors. I-Bot is easy to use and routinely produces imputed values that are highly reliable. I-Bot is described and demonstrated using more than 10 years of California data for daily maximum 8-hr ozone, 24-hr PM2.5 (particulate matter with an aerodynamic diameter <2.5 μm), mid-day average surface temperature, and mid-day average wind speed. I-Bot performance is evaluated by imputing values for observed data as if they were missing, and then comparing the imputed values with the observed values. In many cases, I-Bot is able to impute values for long periods with missing data, such as a week, a month, a year, or even longer. Qualitative visual methods and standard quantitative metrics demonstrate the effectiveness of the I-Bot methodology.Implications: Many resources are expended every year to analyze and interpret data sets from networks of environmental monitors. A large fraction of those resources is used to cope with difficulties due to the presence of missing data. The I-Bot method of imputing values for such missing data may help convert incomplete data sets into virtually complete data sets that facilitate the analysis and reliable interpretation of vital environmental data. 相似文献
10.
Miller JL Miller MJ de Vlaming V Larsen K Smith E Reece K 《Environmental monitoring and assessment》2009,150(1-4):333-349
A number of procedures have been developed to assess toxic effects on the early life stages of salmonid fish. In this study 13 rainbow trout embryo development relatively short-term (7 to 90 day) procedures were reviewed. Three 7-day methods from the published literature and three modifications developed at AQUA-Science (A-S) were evaluated in the laboratory. Based on that evaluation, A-S methods were selected for screening surface water samples (A-S 1) collected in the Sacramento River watershed (California) and for conducting toxicity identification evaluations (TIE) to identify cause(s) of toxicity. Test control performance, test sensitivity, and reference toxicant response variability in the A-S 1 were superior to those in commonly used freshwater toxicity testing methods. The incidence of Sacramento River watershed samples resulting in a notable decrease in embryo development was very low. Of 260 samples screened only 16 (6%) resulted in statistically significant inhibition of embryo development. Of the 16 toxic samples, nine caused minimal (less than 20% abnormal development) and four marginal (less than 30%) toxicity. Samples collected from the agriculture-dominated Colusa Basin Drain and rangeland/forest-dominated Battle Creek on June 16, 2005 caused significant toxicity. TIE procedures indicated that cationic chemicals were the primary cause of toxicity. Metals analysis did not reveal concentrations sufficient to inhibit embryo development, so the most probable cause of toxicity in the two samples was cationic chemicals (perhaps surfactants?) or metals that were not included in the analytical screening. 相似文献