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21.
Stephen Tong Tu'uhevaha Joy Kaitu'u-Lino Susan Philippa Walker Teresa Mary MacDonald 《黑龙江环境通报》2019,39(11):947-957
Fetal growth restriction (FGR) is associated with threefold to fourfold increased risk of stillbirth. Identifying FGR, through its commonly used surrogate—the small-for-gestational-age (SGA, estimated fetal weight and/or abdominal circumference <10th centile) fetus—and instituting fetal surveillance and timely delivery decrease stillbirth risk. Methods available to clinicians for antenatal identification of SGA fetuses have surprisingly poor sensitivity. About 80% of cases remain undetected. Measuring the symphysis-fundal height detects only 20% of SGA fetuses, and even universal third trimester ultrasound detects, at best, 57% of those born SGA. There is an urgent need to find better ways to identify this at-risk cohort. This review summarises efforts to identify molecular biomarkers (proteins, metabolites, or ribonucleic acids) that could be used to better predict FGR. Most studies examining potential biomarkers to date have utilised case-control study designs without proceeding to validation in independent cohorts. To develop a robust test for FGR, large prospective studies are required with a priori validation plans and cohorts. Given that current clinical care detects 20% of SGA fetuses, even a screening test with ≥60% sensitivity at 90% specificity could be clinically useful, if developed. This may be an achievable aspiration. If discovered, such a test may decrease stillbirth. 相似文献
22.
Contaminated sediments are receiving increasing recognition around the world, leading to the development of various sediment quality indicators for assessment, management, remediation, and restoration efforts. Sediment chemistry represents an important indicator of ecosystem health, with the concentrations of contaminants of potential concern (COPCs) providing measurable characteristics for this indicator. The St. Louis River Area of Concern (AOC), located in the western arm of Lake Superior, provides a case study for how numerical sediment quality targets (SQTs) for the protection of sediment-dwelling organisms can be used to support the interpretation of sediment chemistry data. Two types of SQTs have been established for 33 COPCs in the St. Louis River AOC. The Level I SQTs define the concentrations of contaminants below which sediment toxicity is unlikely to occur, whereas the Level II SQTs represent the concentrations that, if exceeded, are likely to be associated with sediment toxicity. The numerical SQTs provide useful tools for making sediment management decisions, especially when considered as part of a weight-of-evidence approach that includes other sediment quality indicators, such as sediment contaminant chemistry and geochemical characteristics, sediment toxicity, and benthic macroinvertebrate community structure. The recommended applications of using the numerical SQTs in the St. Louis River AOC include: designing monitoring programs, interpreting sediment chemistry data, conducting ecological risk assessments, and developing site-specific sediment quality remediation targets for small, simple sites where adverse biological effects are likely. Other jurisdictions may benefit from using these recommended applications in their own sediment quality programs. 相似文献
23.
Gabriele Gerlach Andrea Hodgins-Davis Bradley MacDonald Rebecca C. Hannah 《Behavioral ecology and sociobiology》2007,61(11):1765-1770
Zebrafish (Danio rerio) larvae prefer the olfactory cues of kin to non-kin. We examined the potential benefits of kin preference by comparing growth
rate, shoaling, and aggressive behavior in juvenile zebrafish housed in groups of either familiar kin or unfamiliar non-kin.
Over an observation period of 5 days, the animals grew 33% more in kin groups; however, neither shoaling nor the frequency
of aggressive interactions was different in groups of related versus unrelated individuals. Shoaling behavior increased with
increasing observation time and increasing age, while aggressive behavior remained the same. We conclude that associating
with kin probably creates a less stressful environment that allows for higher growth rates, which can lead to higher direct
fitness based on increased survival and earlier reproduction. Kin recognition leading to kin-structured groups may therefore
be under positive selection. 相似文献
24.
Previous studies have shown that large numbers of ciliated and nonciliated epithelial cells (diam.: 6 to 15 μm) are released
by adult sea scallops, Placopecten magellanicus (Gmelin), during summer months in Newfoundland when water temperatures are at a maximum and gonads are well developed. Such
exfoliation of cells could be a response to stresses associated with elevated water temperatures and/or spawning activity.
In the present study an electronic particle counter/sizer was used to further investigate the factors that influence exfoliation
of epithelial cells by juvenile and adult scallops throughout the year. We observed release of epithelial cells from juveniles,
and from adults collected in months when gametogenic activity was minimal, indicating that exfoliation does not occur as a
result of reproductive activity alone. SEM analysis revealed little difference in surface characteristics of the gills, mantle
and gonad between scallops that had released cells and those that had not, suggesting that exfoliation of small numbers of
cells may be a consequence of cellular turnover and normal physiological function. Adult scallops were monitored in a second
experiment to determine the effects of raising water temperatures from 8.5 to 14.7 and to 21.0 °C on the frequency (proportion)
and rate of cellular exfoliation. Only at the highest experimental temperature (21.0 °C) were exfoliation rates significantly
higher than rates recorded at 8.5 or 14.7 °C. SEM analyses revealed some damage to gill, mantle and gonad tissues when scallops
were exposed to 14.7 and then to 21.0 °C for a total of 8 d.
Received: 21 August 1996 / Accepted: 13 September 1996 相似文献
25.
Peter G. Beninger J. Evan Ward Bruce A. MacDonald Raymond J. Thompson 《Marine Biology》1992,114(2):281-288
The technique of endoscopic video observation was used to study feeding processes of Placopecten magellanicus (Gmelin), collected from Bull Arm, Newfoundland in August 1991 and 1992, under near-natural feeding conditions. The fate of captured particles depended on the extent of ingestive or handling capacity saturation. Under low (1 to 10 particles l-1) to medium (10 to 20 particles l-1) particle concentrations, most particles were incorporated in continuous anteriorly directed slurries in the dorsal ciliated tracts of the gill arch and dorsal bends. As particle concentration or exposure time to the lower particle concentrations increased, four endogenous mechanisms of ingestion volume control were increasingly observed: (1) rejection of dense mucus-particle masses from the principal filament troughs onto the ventrally beating cilia and associated currents of the ordinary filament plicae, counter to and below the incoming pallial current maintained by the principal filament cilia; (2) intermittent stopping of the anteriorward flow in the dorsal ciliated tracts; (3) reduction or cessation of input from the principal filaments to the dorsal ciliated tracts; (4) detachment of the dorsal bends from the mantle to establish a shunt from the infrabranchial to the suprabranchial cavity. Chemical and histochemical tests of purified fluid withdrawn from the dorsal ciliated tracts indicate that mucus is present at all particle concentrations. Mucus therefore participates both in normal feeding and in ingestion volume control on the bivalve gill, although different mechanisms, and types of mucus, effect transport of material in the dorsal (feeding) and ventral (cleaning) ciliated tracts. 相似文献
26.
MacDonald AM Matthews KB Paterson E Aspinall RJ 《Environmental pollution (Barking, Essex : 1987)》1994,83(1-2):245-250
The likely impact of climate change on the moisture regime of Scottish soils and consequently on agriculture and land use has been addressed using a novel Geographic Information Systems (GIS) approach. Current estimates of changes in summer precipitation by the year 2030 are 0% with an associated uncertainty of +/- 11%. This study considers the worst case scenario of a decrease in rainfall by 11% which will lead to some low rainfall areas experiencing an increased drought risk, particularly on lighter soils. Wet areas with heavy soils could benefit from an increase in the accessibility period for machinery. As the major agricultural land in Scotland is located on the relatively dry east coast where localised problems due to drought are not uncommon even under the present climate, the detrimental effects of a decrease in rainfall for the whole of Scotland are therefore likely to outweigh the benefits. Approximately 8% of Scotland has been identified in this study as soil/climate combinations which will be susceptible to drought should summer rainfall decrease by 11% and summer temperature increase by 1.4 degrees C. 相似文献
27.
This research has developed mathematical models for computing lifetime greenhouse gas (GHG) emissions associated with materials. The models include embodied carbon (EC) emissions from the manufacture of materials, and GHG emissions from incineration, or landfill gas (LFG) production from landfill disposal of the material beyond their service lives. The models are applicable to all materials; however, their applications here are demonstrated for the lumber from a residential building with 50- and 100-year service lives, and with incineration, landfill, and deconstruction as end-of-life treatments. This paper introduces a new metric for lifetime GHG emissions associated with materials termed “Global Warming Impact of Materials (GWIM).” The GWIM is subdivided into two portions: (i) productive portion (GWIMp) that includes the materials’ emissions until the service life of the facility and (ii) non-productive portion (GWIMnp) which includes the materials’ GHG emissions beyond the service life until they are eliminated from the atmosphere. In place of the current, static, EC measurements (kgCO2e or MTCO2e), this model reports the GWIMs in units of kgCO2e-years or MTCO2e-years, which includes the effects of “time of use” of a facility. Using the models, this paper has computed GHG reductions by deconstruction, with material recoveries of 30%, 50%, and 70% at demolition for reuse, recycle, or repurpose. A 70% material recovery, after a 50-year service life of the building, affected a savings of 47% and 52% if the remaining 30% debris was incinerated or landfilled respectively. All of the values computed using models checked out with manual calculations. 相似文献
28.
29.
C. David Cooper Brian Kim John MacDonald 《Journal of the Air & Waste Management Association (1995)》2013,63(4):471-476
ABSTRACT A new equation is proposed to predict the lower heating value of hazardous and non-hazardous materials. The equation was developed by a statistical correlation of heating value and composition data for a variety of materials as reported in a number of sources. The model takes into account the carbon, hydrogen, oxygen, chlorine, and sulfur content of the material being combusted. 相似文献
30.
Bryce I. MacDonald 《Journal of the Air & Waste Management Association (1995)》2013,63(5):525-528
Achievement of air quality goals now more than ever requires careful consideration of alternative control strategies in view of national concerns with energy and the economy. Three strategies which might be used by coal-fired steam electric plants to achieve ambient air quality standards for sulfur dioxide have been compared, and the analysis shows that the desired objective can be achieved using the intermittent control strategy with substantially less impact on the environment, less consumption of energy, and at a much lower economic cost than using either stack gas scrubbing or low-sulfur coal. 相似文献