The utility of electrocardiography and echocardiography in copper deficiency-induced cardiac damage in goats

Environmental Science and Pollution Research - Copper deficiency (CuD) is a common mineral disorder in ruminants, which causes histomorphological changes in the heart due to disturbances in...     

Bias correction of regional climate model simulations for the impact assessment of the climate change in Egypt

This study projected the future temperature change for Egypt during the late of this century (2071–2100) for three representative concentration pathways (RCP2.6, RCP4.5, and RCP8.5), by correcting regional climate model (RCM) simulations of average, maximum, and minimum daily temperature with reference to observed data of 26 stations. Four commonly used methods of bias correction have been applied and evaluated: linear scaling, variance scaling, and theoretical and empirical quantile mapping. The compromise programing results of the applied evaluation criteria show that the best method is the variance scaling, and thus it was applied to transfer the correction factor to the projections. All temperature indices are expected to increase significantly under all scenarios and reach the highest record by the end of the century, i.e., the expected increase in average, maximum, and minimum temperature ranges between 4.08–7.41 °C, 4.55–7.89 °C, and 3.88–7.23 °C, respectively. The largest temperature rise will occur in the summer, with the highest increase in the maximum (minimum) temperature of 10.9 °C (10 °C) in July and August under RCP8.5. The maximum (minimum) winter temperature, on the other hand, will drop by a maximum of 2 °C (1.35 °C) under RCP2.6. The Western Desert and Upper Egypt are the regions most affected by climate change, while the northern region of Egypt is the least affected. These findings would help in impact assessment and adaptation strategies and encourage further investigation to evaluate various climate models in order to obtain a comprehensive assessment of the climate change impacts on different hydrometeorological processes in Egypt.

     

Office Ergonomics: Deficiencies in Computer Workstation Design

The objective of this research was to study and identify ergonomic deficiencies in computer workstation design in typical offices. Physical measurements and a questionnaire were used to study 40 workstations. Major ergonomic deficiencies were found in physical design and layout of the workstations, employee postures, work practices, and training. The consequences in terms of user health and other problems were significant. Forty-five percent of the employees used nonadjustable chairs, 48% of computers faced windows, 90% of the employees used computers more than 4 hrs/day, 45% of the employees adopted bent and unsupported back postures, and 20% used office tables for computers. Major problems reported were eyestrain (58%), shoulder pain (45%), back pain (43%), arm pain (35%), wrist pain (30%), and neck pain (30%). These results indicated serious ergonomic deficiencies in office computer workstation design, layout, and usage. Strategies to reduce or eliminate ergonomic deficiencies in computer workstation design were suggested.     

Optimization of Headspace Solid Phase Microextraction Procedure for Trace Analysis of Toluene

This study describes optimization of headspace solid phase microextraction followed by gas chromatography equipped with a flame ionization detector for toluene at trace level in spiked urine. The parameters affecting the extraction and gas chromatographic determination of analytes were studied: extraction time and temperature; desorption time and temperature; addition of NaCl; and pH, volume and agitation of the sample. Optimized headspace extraction was carried out at 30 °C for 6 min in the presence of 0.2 g-m^-1of NaCl in the sample solution. Also, sample volume and sample pH were optimized at 5 ml and 7 (neutral pH), respectively. Desorption of the analytes was carried out at 250 °C for 60 s. The optimized procedure was validated with 3 different pools of spiked urine; it showed good reproducibility over 6 consecutive days and 6 within-day experiments. The study also determined the accuracy, linearity and detection limits of this method.     

Saddle seat reduces musculoskeletal discomfort in microsurgery surgeons

Background. Microsurgery is a surgical procedure requiring a high degree of precision and is commonly facilitated through the use of an intraoperative microscope. When operating the microscope system, the long-term posture leads to musculoskeletal disorders in surgeons, and seats are commonly employed to diminish these problems. The present study was conducted to evaluate musculoskeletal discomfort during work with a saddle seat in comparison with conventional seats for microscopic work. Methods. Two types of seats, a saddle and a conventional one, were evaluated for 73 microsurgical surgeons in terms of musculoskeletal discomfort. Corlett and Bishop's body part discomfort scale was used to assess musculoskeletal discomfort before and after working with the seats. Results. The highest amount of discomfort that microsurgical surgeons acquire in the workplace was focused on their neck, shoulders, arms and back. During work with a saddle seat, a significant reduction was found for discomfort values in the neck, shoulder, arm, back, elbow and forearm, as well as the whole body (p?<?0.05). Conclusion. This study showed that the use of saddle seats provides a more appropriate physical posture at work, and can decrease musculoskeletal discomfort in different parts of the body of microsurgical surgeons.     

Natural organic compounds as alternative to methyl bromide for nematodes control

Thirty-three organic acids and furfural metabolites were examined for their nematicidal activity against plant-parasitic, free-living and predacious nematodes. Propionic acid, 2-methylhexanoic acid, lactic acid, maleic acid, and furic acid were the most effective nematicides among normal chain organic acids, branched organic acids, hydroxy/keto-acids, dicarboxylic acids and furfural metabolites, respectively. Seven of the tested compounds were found to have more than 90% mortality thus designating them as highly active nematicides. Of the highly active tested compounds, an average octanol/water log P of 0.97 was observed with a range from 0.28 to 2.64, and a Henry's Law constant averaging 2.6 × 10^{? 7} atm.m³/mole. Tested chemicals with minor or low nematicidal activity showed an average log P of 1.76 with a range from 0.15 to 3.42 and a Henry's Law constant averaging 16.6 × 10^{? 7} atm.m³/mole.     

Gamma aminobutyric acid radioreceptor‐assay a possible biomarker for human exposure to certain agrochemicals

Abstract

Cyclodiene insecticides, hexachlorocyclohexanes, pyrethroids, bicyclophosphates, the bicycloorthocarboxylate insecticides and some of their metabolites and environmental degradation products are central nervous system toxicants with high specific binding affinity to the chloride channel of the γ‐ aminobutyric acid (GABA)_A receptor‐ionophore sites. [³⁵S] tertiary‐butylbicyclophosphorothionate (TBPS) with specific activity higher than 60 Ci/mmole has a high binding affinity to the same sites and is now commercially available and can be used to label the GABA_A receptor for the development of a radioreceptor assay technique. The GABA receptor was prepared by ultra centnfugation and dialysis of brain homogenates of either cow, goat, rat or catfish. The receptor was then labeled with [³⁵S] TBPS and the assay was conducted by measuring the displacement of radioactivity following incubation with samples containing the analytes. A radioreceptor assay protocol was developed to measure the amount of the α‐endosulfan in blood samples. The assay was extremely sensitive, and can detect 0.2 nM of endosulfan at a level equivalent to 0.08 ppb or 8x10^‐11 gm of endosulfan in each ml of the blood samples.     

Distribution of Alkalinity,Ph, Salinity and Carbon Dioxide Components in the Coastal Waters of Alexandria

The ara studied is located between El-Dikheila Harbour in Elmex Bay and Mandara, at longitude 29° 47′ and 30° East and latitude 31° 17′ North. the aim of the work is to look at carbon dioxide components in this areA and the effect of waste water discharged on their concentrations. Surface and bottom water samples were collected from 12 stations during January, April, August and November, 1995. Total alkalinity, salinity, temperature and pH were measured. Carbonate alkalinity, total alkalinity, partial pressure and dissolved carbon dioxide, carbonate and bicarbonate ions were calculated, since the studied area includes two differetn sources of pollution. It wAs found conventient to refer El-Mex Bay as region “A” which contains stations from I to VI and the area located between Kayet Bey outfall and Mandara which contains stations from VII to XII as region “B”. When specific alkalinity is used As A tracer for El-Umum drain water it is observed that the drain water could reach Sidi Bishr area especially in August and November, while in January and April drain water did not reach this area.     

Occurrence and ecotoxicological risk assessment of pesticides in sediments of the Rosetta branch, Nile River, Egypt

This study aimed to (1) monitor the occurrence and spatiotemporal variations of 100 pesticides in sediments collected monthly from July 2018 to June 2019 from sampling sites in El-Rahawy, Sabal, and Tala, along the Rosetta branch of the Nile River, Egypt, and (2) perform an ecological risk assessment for aquatic organisms upon exposure to the detected sediment pesticides based on the risk quotient (RQ) method. Out of the 100 pesticides monitored, 16 pesticides belonging to seven chemical families were detected, and 55% of the sediment samples were contaminated with one or more pesticide residues. The mean concentration (mg/kg dry weight (dw)) and detection frequency (%) of the four most frequently detected pesticides in the sediment samples were as follows: chlorpyrifos (0.18 mg/kg dw and 34%), p,p′-DDE (0.018 mg/kg dw and 30%), cypermethrin (0.03 mg/kg dw and 14%), and deltamethrin (0.026 mg/kg dw and 13%). The spatial distribution exhibited that El-Rahawy had the highest pesticide load (2.86 mg/kg dw) among the studied sites, whereas the temporal variations revealed that the highest total pesticide concentrations were detected in winter season (1.73 mg/kg dw). Meanwhile, 12 pesticides showed high RQs (>1), posing a potential ecological risk to aquatic species that live and feed on such sediments.