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81.
Y. J. Yao M. R. Khan C. P. Ong H. K. Lee S. F. Y. Li 《Environmental monitoring and assessment》1991,19(1-3):83-91
Optimization procedures for the reversed-phase separations of six phthalates using the isoselective multisolvent gradient elution (IMGE) system are described. A systematic experimental design has been employed to gather retention data on the compounds in a mixture. The data were then fitted into a second-order polynomial equation and an overlapping resolution mapping (ORM) technique of data analysis was subsequently used to establish the optimum solvent mixture for the highest resolution of all adjacent peaks in the chromatogram. 相似文献
82.
双酚A暴露对斑马鱼胚胎期代谢作用的影响 总被引:1,自引:1,他引:0
端正花 朱琳 赵娜 卜文俊 Lam Siew Hong Gong Zhiyuan 邹莉 李巍 Ong Eng Shi Ong Choon Nam 《中国环境科学》2009,29(12):1318-1322
运用基于GC/MS的代谢组学方法,以受精卵在双酚A(BPA)中暴露4d后的斑马鱼胚胎为对象,研究了其体内挥发性和半挥发性代谢组分变化.暴露浓度设定为0,0.5,1.5,4.5mg/L,包括US EPA假定的“安全水平”(1.5mg/L).结果表明,1.5mg/L BPA暴露能使斑马鱼体内花生四烯酸和胆固醇的相对百分含量极显著降低,饱和脂肪酸、氨基酸、葡萄糖和肌糖的相对百分含量显著升高.因此,1.5mg/L BPA能干扰斑马鱼胚胎期的正常代谢. 相似文献
83.
Xiaona Chu Jiangyong Hu Say Leong Ong 《Frontiers of Environmental Science & Engineering in China》2009,3(4):393-403
Proteomics involves the separation of proteins, identification of the amino acid sequence of the interested or target proteins,
study of the function of the proteins, modification, structure and ultimate assignments to functional pathways in the cell.
The proteomic investigations have contributed greatly to human diseases studies, new drugs discovery researches, and environmental
science in recent years. This article provides a review on the development of the main proteomic technologies, including both
the gel based and non-gel based technologies, and their applications in environmental science. Proteomic technologies have
been utilized in the environmental stresses studies to analyze the induction or reduction of proteins at expression level
and identify the target proteins to investigate their function in response to environmental stresses, such as high or low
pH, oxidation stress, and toxic chemicals. Such protein responses are also helpful to understand the mechanisms of some cellular
activities and the functions of some proteins. 相似文献
84.
Environmental Chemistry Letters - Climate change damage induced by growing carbon dioxide (CO2) emissions has rapidly fostered research on capturing, utilizing, and converting CO2 into valuable C1... 相似文献