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Rohana Chandrajith Shanika Nanayakkara Kozuyoshi Itai T. N. C. Aturaliya C. B. Dissanayake Thilak Abeysekera Kouji Harada Takao Watanabe Akio Koizumi 《Environmental geochemistry and health》2011,33(3):267-278
The increase in the number of chronic kidney disease (CKD) patients from the north central region of Sri Lanka has become
a environmental health issue of national concern. Unlike in other countries where long-standing diabetes and hypertension
are the leading causes of renal diseases, the majority of CKD patients from this part of Sri Lanka do not show any identifiable
cause. As the disease is restricted to a remarkably specific geographical terrain, particularly in the north central dry zone
of the country, multidisciplinary in-depth research studies are required to identify possible etiologies and risk factors.
During this study, population screening in the prevalent region and outside the region, analysis of geoenvironmental and biochemical
samples were carried out. Population screening that was carried out using a multistage sampling technique indicated that the
point prevalence of CKD with uncertain etiology is about 2–3% among those above 18 years of age. Drinking water collected
from high-prevalent and non-endemic regions was analyzed for their trace and ultratrace element contents, including the nephrotoxic
heavy metals Cd and U using ICP-MS. The results indicate that the affected regions contain moderate to high levels of fluoride.
The Cd contents in drinking water, rice from affected regions and urine from symptomatic and non-symptomatic patients were
much lower indicating that Cd is not a contributing factor for CKD with uncertain etiology in Sri Lanka. Although no single
geochemical parameter could be clearly and directly related to the CKD etiology on the basis of the elements determined during
this study, it is very likely that the unique hydrogeochemistry of the drinking water is closely associated with the incidence
of the disease. 相似文献
775.
The potential of TNT to accumulate in aquatic organisms was assessed by determining bioconcentration factors for TNT and TNT biotransformation products using two benthic invertebrates (Chironomus tentans and Lumbriculus variegatus), and by determining the bioaccumulation factor of TNT and TNT biotransformation products due to TNT exposure via feeding for channel catfish (Ictalurus punctatus). In all three species, TNT was rapidly biotransformed resulting in minimal accumulation. The bioconcentration factors for parent TNT ranged from 3 to 4 ml g(-1) for the invertebrates studied, while the TNT bioaccumulation factor for catfish via oral exposure of food pellets was 2.4x10(-5) g g(-1) based on the concentration of TNT in the food pellet. As indicated by this small bioaccumulation factor, TNT accumulation in channel catfish through trophic transfer would be negligible compared to aqueous exposure (previously reported BCF of 0.79 ml g(-1)). TNT extractable biotransformation products accumulated to a greater degree than parent TNT for all three species. In addition, a large fraction of the radioactivity within all three species resisted solvent extraction. The highest bioconcentration factors occurred in L. variegatus with extractable radioactivity measuring 76 ml g(-1) and total radioactivity measuring 216 ml g(-1). Because the bioaccumulation of TNT is very low compared to the bioaccumulation of its biotransformation products, further research including identifying and determining the relative toxicities of these biotransformation products is necessary to fully evaluate the environmental risk posed by exposure to TNT. 相似文献
776.
A database has been developed that demonstrates experimental evidence of hormesis. It includes information from a broad range of biological models, including plants, and information on study design, dose-response features, and physical/chemical properties of the agents. An assessment of plant hormetic dose responses is presented based on greater than 3000 plant endpoints. Plant hormetic dose responses were observed for numerous endpoints including disease incidence, reproductive indices, mutagenic endpoints, various metabolic parameters, developmental processes, and a range of growth indicators. Quantitative features of these dose responses typically display a maximum stimulatory response less than two-fold greater than controls and a width of the stimulatory response usually less than 10-fold in dose range. The database establishes that hormetic dose responses commonly occur in plants, are broadly generalizable, and have quantitative features similar to hormetic dose responses found for animals. 相似文献
777.
Reid SB Pollard EK Sullivan DC Shaw SL 《Journal of the Air & Waste Management Association (1995)》2010,60(12):1452-1462
Lawn and garden equipment are a significant source of emissions of volatile organic compounds (VOCs) and other pollutants in suburban and urban areas. Emission estimates for this source category are typically prepared using default equipment populations and activity data contained in emissions models such as the U.S. Environmental Protection Agency's (EPA) NONROAD model or the California Air Resources Board's (CARB) OFFROAD model. Although such default data may represent national or state averages, these data are unlikely to reflect regional or local differences in equipment usage patterns because of variations in climate, lot sizes, and other variables. To assess potential errors in lawn and garden equipment emission estimates produced by the NONROAD model and to demonstrate methods that can be used by local planning agencies to improve those emission estimates, this study used bottom-up data collection techniques in the Baltimore metropolitan area to develop local equipment population, activity, and temporal data for lawn and garden equipment in the area. Results of this study show that emission estimates of VOCs, particulate matter (PM), carbon monoxide (CO), carbon dioxide (CO2), and nitrogen oxides (NO(x)) for the Baltimore area that are based on local data collected through surveys of residential and commercial lawn and garden equipment users are 24-56% lower than estimates produced using NONROAD default data, largely because of a difference in equipment populations for high-usage commercial applications. Survey-derived emission estimates of PM and VOCs are 24 and 26% lower than NONROAD default estimates, respectively, whereas survey-derived emission estimates for CO, CO2, and NO(x) are more than 40% lower than NONROAD default estimates. In addition, study results show that the temporal allocation factors applied to residential lawn and garden equipment in the NONROAD model underestimated weekend activity levels by 30% compared with survey-derived temporal profiles. 相似文献
778.
The distribution of arsenic in the stems of fruit trees grown in soils exposed to arsenical pesticides has been studied using neutron activation analysis. The results show arsenic to be confined mainly to heartwood near the pith and active xylem tissue in the most recent annual growth rings. These results suggest that dendroanalysis for arsenic in fruit trees will not yield a reliable chronology of arsenic exposure. 相似文献
779.
Y. P. Kim K. -C. Moon S. -G. Shim J. H. Lee J. Y. Kim K. Fung G. R. Carmichael C. H. Song C. H. Kang H. -K. Kim C. B. Lee 《Atmospheric environment (Oxford, England : 1994)》2000,34(29-30)
Organic carbon (OC) and elemental carbon (EC) in fine particles (PM2.5) at two background sites, Kosan and Kangwha in Korea were measured during intensive field studies between 1994 and 1999. Fine particles were collected on pre-fired quartz filters in a low-volume sampler and analyzed using the selective thermal oxidation method with MnO2 catalyst. The OC and EC concentrations at Kosan located at western tip of Cheju Island in southern Korea are lower than those at Kangwha located at western coastal area in mid-Korean peninsula. Still, the OC concentrations at Kosan are generally higher than those at other background areas in Japan and USA. The EC concentrations at Kosan are lower than or comparable to those at other background areas. The total carbon (TC, sum of OC and EC) to EC ratio values at both sites were higher than those at other background areas in Japan and USA. At Kosan, the OC and EC concentrations when air parcels were from southern China were higher than those when air parcels were coming from northern China. However, at Kangwha, the differences were statistically not clear since most air parcels were from northern China. Except when air parcels were from the North Pacific during summer, the OC and EC concentrations are well correlated indicating that both OC and EC share the same emission/transport characteristics. From the gaseous hydrocarbon data and the OC and EC relationship, it was found that during summer local biogenic emissions of OC might be significant at Kosan. 相似文献
780.
Rumbold DG Bruner MC Mihalik MB Marti EA 《Environmental pollution (Barking, Essex : 1987)》1997,96(1):99-105
Tetrachlorodibenzo-p-dioxin (TCDD), tetrachlorodibenzofuran (TCDF) and selected metal concentrations were measured in eggs and nestlings of anhingas (Anhinga anhinga) and white ibises (Eudocimus albus) collected from a colony next to a municipal solid-waste (MSW) combustor and ash landfill. Most of the measured residues, including TCDD, TCDF, arsenic, beryllium, cadmium and nickel, remained at pre-operational levels during the first five years of facility operation. Selenium (in anhingas) and mercury (in both anhingas and ibises) occurred at their lowest concentrations in samples collected during the fifth year of facility operation (Year-5). Alternatively, concentrations of lead in ibis nestlings were highest in Year-1 and Year-5 compared to Year-0. The MSW combustor could neither be ruled out nor confirmed as the source of this lead. 相似文献