Effect of the zero-tolerance drinking and driving law on mortality due to road traffic accidents according to the type of victim,sex, and age in Rio de Janeiro,Brazil: An interrupted time series study

Objective: The objective of this study was to estimate the effect of the Brazilian zero-tolerance drinking and driving law on mortality rates due to road traffic accidents according to the type of victim, sex, and age.

Methods: An interrupted time series design was used to compare yearly mortality rates due to road traffic accidents in Rio de Janeiro, Brazil, before and after the zero-tolerance drinking and driving law came into effect on June 19, 2008. Yearly mortality rates were compared according to the type of victim: pedestrian, cyclist, motorcyclist, and vehicle occupant. We used the Prais-Winsten procedure of autoregression in the analysis of time series; the outcome of this analysis was the annual percentage change in the rates. Overall and stratified analyses were conducted to investigate whether the zero-tolerance drinking and driving law may have had a distributional effect on mortality rates due to road traffic accidents depending on sex and age group; a significance level of P < .01 was accepted.

Results: From 1999 to 2016, there were 15,629 deaths due to road traffic accidents in Rio de Janeiro. The effect of the zero-tolerance drinking and driving law on overall mortality rates due to road traffic accidents in Rio de Janeiro was not statistically significant. However, among cyclists and motorcyclists aged ≥60 years and among pedestrians of both sexes and aged ≥20 years, the effect of the zero-tolerance drinking and driving law was to decrease mortality due to road traffic accidents at a yearly rate.

Conclusion: There is evidence of reduced mortality rates due to road traffic accidents among cyclists and motorcyclists aged ≥60 years and among pedestrians of both sexes aged ≥20 years in the second major Brazilian capital 9 years after the zero-tolerance drinking and driving law was adopted.     

Governance and Standardization in Fish Value Chains: Do They Take Care of Key Animal Welfare Issues?

Journal of Agricultural and Environmental Ethics - Innovation in fisheries is a global development that focuses on a broad range of aims. One example is a project that aims to develop technology...     

Auramine dyes induce toxic effects to aquatic organisms from different trophic levels: an application of predicted non-effect concentration (PNEC)

Environmental Science and Pollution Research - The dyes Auramine and Auramine O are used in several industrial products, despite the scarce information regarding their ecotoxicity. The aim of the...     

Spontaneous abortion in women occupationally exposed to inhalational anesthetics: a critical systematic review

Environmental Science and Pollution Research - Occupational exposure to inhalational anesthetics has been associated with health problems, including reproductive issues. Considering the scarcity...     

Kinetics assessment and modeling of biogas production by anaerobic digestion of food wastes and acclimated sewage sludge

Journal of Material Cycles and Waste Management - In this work, food wastes (FWs) and domestic sewage sludge (DSS) were used as raw materials for energy recovery by anaerobic digestion (AD). AD was...     

Model for sustainability implementation and measurement in construction sites

Sustainable practices at construction sites should be considered from the start of the project, meaning during the design phase. A model for the implementation of sustainability at a site is an important management tool, and its adoption can indicate good practices and propose an assessment of local conditions. Thus, the main contribution of this article is to propose a practical model to evaluate the level of implementation of sustainable practices at construction sites. The model was based on sustainability certifications and validated at six construction sites in Brazil. The results indicate that construction companies that possess environmental certifications have better levels of implementation of good practices at their work sites. However, it was noted that it is not necessary for a company to obtain an environmental certification; rather, it is necessary for sustainability strategies to become corporate culture.     

Ketoprofen Loaded in Natural Rubber Latex Transdermal Patch for Tendinitis Treatment

Ketoprofen is an analgesic with potent anti-inflammatory activity against acute inflammation, subacute inflammation, for the acute and long-term treatment of various inflammatory pathologies, as rheumatoid arthritis and colonic adenocarcinoma. In order to minimize the incidence of systemic events related to ketoprofen, the transdermal drug delivery system development has been most important. The advantages of using natural rubber latex membranes include not only the reduction of adverse systemic events, but also the suitability of the low cost of the material together with its physicochemical properties such as flexibility, mechanical stability, surface porosity and water vapor permeability, and besides being a biocompatible material also presents biological activity to stimulate the angiogenesis, being able to be used in tissue repair. This study demonstrated that ketoprofen was successfully incorporated into natural latex membranes for drug delivery. FTIR indicated that the drug did not interact chemically with the membrane. Moreover, the natural latex membranes released 60% of the ketoprofen incorporated in 50 h. SEM images indicated that a portion of the drug was present on the membrane surface, being this portion responsible for the burst release. The tensile tests showed that the addition of the drug into the natural latex membrane did not influence on the polymer mechanical behavior. In addition, drug-natural latex membranes presented no red blood cell damaging effects. Our data shows that the ketoprofen loaded natural latex membranes is a promising system for sustained drug delivery which can be used to minimize the adverse side effects of high dose systemic drug delivery.     

Cork stoppers as an effective sorbent for water treatment: the removal of mercury at environmentally relevant concentrations and conditions

The technical feasibility of using stopper-derived cork as an effective biosorbent towards bivalent mercury at environmentally relevant concentrations and conditions was evaluated in this study. Only 25 mg/L of cork powder was able to achieve 94 % of mercury removal for an initial mercury concentration of 500 μg/L. It was found that under the conditions tested, the efficiency of mercury removal expressed as equilibrium removal percentage does not depend on the amount of cork or its particle size, but is very sensitive to initial metal concentration, with higher removal efficiencies at higher initial concentrations. Ion exchange was identified as one of the mechanisms involved in the sorption of Hg onto cork in the absence of ionic competition. Under ionic competition, stopper-derived cork showed to be extremely effective and selective for mercury in binary mixtures, while in complex matrices like seawater, moderate inhibition of the sorption process was observed, attributed to a change in mercury speciation. The loadings achieved are similar to the majority of literature values found for other biosorbents and for other metals, suggesting that cork stoppers can be recycled as an effective biosorbent for water treatment. However, the most interesting result is that equilibrium data show a very rare behaviour, with the isotherm presenting an almost square convex shape to the concentration axis, with an infinite slope for an Hg concentration in solution around 25 μg/L.     

CircSiZer: an exploratory tool for circular data

Smoothing methods and SiZer (SIgnificant ZERo crossing of the derivatives) are useful tools for exploring significant underlying structures in data samples. An extension of SiZer to circular data, namely CircSiZer, is introduced. Based on scale-space ideas, CircSiZer presents a graphical device to assess which observed features are statistically significant, both for density and regression analysis with circular data. The method is intended for analyzing the behavior of wind direction in the atlantic coast of Galicia (NW Spain) and how it has an influence over wind speed. The performance of CircSiZer is also checked with some simulated examples.